3 Biotech

, 8:138 | Cite as

World market and biotechnological production of itaconic acid

  • Juliana Cunha da CruzEmail author
  • Aline Machado de Castro
  • Eliana Flávia Camporese Sérvulo
Review Article


The itaconic acid (IA) world market is expected to exceed 216 million of dollars by 2020 as a result of an increasing demand for bio-based chemicals. The potential of this organic acid produced by fermentation mainly with filamentous fungi relies on the vast industrial applications of polymers derived from it. The applications may be as a superabsorbent polymer for personal care or agriculture, unsaturated polyester resin for the transportation industry, poly(methyl methacrylate) for electronic devices, among many others. However, the existence of other substitutes and the high production cost limit the current IA market. IA manufacturing is done mainly in China and other Asia–Pacific countries. Higher economic feasibility and production worldwide may be achieved with the use of low-cost feedstock of local origin and with the development of applications targeted to specific local markets. Moreover, research on the biological pathway for IA synthesis and the effect of medium composition are important for amplifying the knowledge about the production of that biochemical with great market potential.


Bio-based chemicals Bio-based polymers Fungal fermentative processes Itaconic acid Itaconic acid polymers Itaconic acid trading market Sustainable materials 



The authors thank Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) for the financial support of this work.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest in the publication.


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© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Escola de QuímicaUniversidade Federal do Rio de Janeiro, 2030, Centro de TecnologiaRio de JaneiroBrazil
  2. 2.Divisão de BiotecnologiaCentro de Pesquisa e Desenvolvimento, PETROBRAS, Av. Horácio MacedoRio de JaneiroBrazil

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