In Memoriam: Dr. Bernard Fisher
Very few individuals have so profoundly influenced the field of surgical oncology as has Dr. Bernard Fisher, who died on October 16, 2019, at the age of 101. Fisher is widely known for his work on the treatment and prevention of primary breast cancer, where he championed breast-conserving surgery, the use adjuvant systemic therapies, and chemoprevention (i.e., the use of anti-estrogens to prevent breast cancer). However, Fisher’s impact extends far beyond the field of surgical oncology. He questioned the value of observational studies in clinical decision-making and emphasized that large randomized trials with unambiguous endpoints (i.e., all-cause mortality) should form the basis for patient management.