Gynecological Cancers—the Changing Paradigm

Review Article


Outstanding research in the last few decades led to newer insights into the management of gynecological cancers. In the preventive arena, the efficacy and safety of HPV vaccination are well accepted and is now in addition to bi- and quadrivalent vaccines; there is a nonavalent vaccine against nine oncogenic HPV strains. Recent studies also looked into the dosaging schedules and age of vaccination against HPV to improve the vaccine efficacy and coverage. HPV testing is now approved as a primary screening test for cervical cancer in women aged more than 30 years with better sensitivity than the traditional cytology. Opportunistic salpingectomy for ovarian cancer prevention and neoadjuvant chemotherapy for advanced ovarian cancers are accepted practices. The role of personalized medicine in ovarian cancer and comprehensive genomic analysis of endometrial cancers are also covered in this review.


Gynecological cancers HPV vaccination Personalized treatment Molecular characterization endometrial cancers 


Compliance with Ethical Standards

Ethical Statement

This is a review article and did not include the study of patients, medical records, or volunteers, so as per our institutional guidelines, this article did not require the approval of a hospital ethical committee. The research did not include human or animal participants.

Conflict of Interest

The author declares no conflict of interest.


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Copyright information

© Indian Association of Surgical Oncology 2018

Authors and Affiliations

  1. 1.Division of GynaeoncologyRegional Cancer CentreTrivandrumIndia

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