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Indian Journal of Surgical Oncology

, Volume 9, Issue 4, pp 558–564 | Cite as

Decadal Experience of Renal Cell Carcinoma from a Tertiary Care Teaching Institute in North India

  • Singh KawaljitEmail author
  • Sinha Rahul Janak
  • Gupta Ashok
  • Singh Vishwajeet
Original Article
  • 13 Downloads

Abstract

To study the current trends of renal cell carcinoma (RCC) in terms of demographic characteristics, clinical presentation, staging, mode of management, histopathology, and survival characteristics from a high volume tertiary care teaching institute in North India. We retrospectively reviewed the records of all patients of RCC between January 2006 and December 2015 and variables like age, gender, symptoms, tumor size/location/number, stage, type of surgery, histopathology, and survival characteristics were studied. One hundred forty-four patients were included in the study. Most common age group of presentation was 50–59 years (29.8%), male to female ratio was 2.5, and majority of cases were smokers. Flank pain was the most common presenting complaint (38.2%), classical triad (pain, fever, hematuria) was present in 25%, and incidental diagnosis was made in 11.1% cases. Stage T2a was most common presentation with majority of tumors present in upper pole (27.1%). Renal vein involvement (T3a) was present in 10.4%, hilar lymph node involvement in 25%, and distant metastasis was observed in 20.1% cases. Radical nephrectomy was most common surgery performed (75%) and clear cell carcinoma was the most common histopathology (75.7%) followed by papillary (11.1%). Women reported more chromophobe type and low-grade cancers, although rest of clinico-pathological features did not show any gender difference. Mean follow-up of the study was 6–122 months with younger (< 29 years) patients reporting lower 5-year survival and higher stage disease. Renal cell carcinoma shows a different trend in our study population, compared to western data, with large size tumors and advanced stage presentation being more common.

Keywords

Renal cell carcinoma Radical nephrectomy Partial nephrectomy Laparoscopic nephrectomy 

Notes

Acknowledgements

The authors would like to acknowledge their family, friends, and patients for their constant support and motivation in writing this manuscript.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

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Copyright information

© Indian Association of Surgical Oncology 2018

Authors and Affiliations

  • Singh Kawaljit
    • 1
    Email author
  • Sinha Rahul Janak
    • 1
  • Gupta Ashok
    • 1
  • Singh Vishwajeet
    • 1
  1. 1.Department of UrologyKing George’s Medical UniversityLucknowIndia

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