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Indian Journal of Surgical Oncology

, Volume 9, Issue 4, pp 618–621 | Cite as

Occult Gallbladder Carcinoma Presenting as a Primary Ovarian Tumour: a Case Report and Review of Literature

  • Shipra SonkusareEmail author
  • S. Vishwanath
  • Prabhneet Kaur
  • Pujitha Murthi
  • Krishnapriya
Case report
  • 10 Downloads

Abstract

The ovary is a common site of metastasis from various organs. However, little is known about gallbladder carcinoma metastasising to the ovaries and presenting as a primary ovarian tumour. We report a case of a metastatic gallbladder carcinoma which mimicked a primary ovarian tumour in a 31-year-old woman who presented with menstrual symptoms and an ovarian mass without obvious signs and symptoms related to gallbladder carcinoma. Postoperatively histopathological examination diagnosed primary ovarian germ cell tumour for further chemotherapy. However, postoperative re-evaluation with radiology suggested the possibility of a primary gallbladder carcinoma. Exact diagnosis could only be made after repeat histopathological evaluation of the ovarian mass.

Keywords

Gallbladder carcinoma Ovarian metastasis Adenocarcinoma of the ovary 

Notes

Compliance with Ethical Standards

Consent

Written informed consent was obtained from the patient for publication of this case report and accompanying images.

Conflict of Interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Petru E, Pickel M, Heydarfadai M, Lahousen M, Haas J, Schaider H, Tamussino K (1992) Nongenital cancers metastatic to the ovary. Gynecol Oncol 44:83–86CrossRefGoogle Scholar
  2. 2.
    Meriden Z, Yemelyanova AV, Vang R, Ronnett BM (2011) Ovarian metastases of pancreaticobiliary tract adenocarcinomas: analysis of 35 cases, with emphasis on the ability of metastases to simulate primary ovarian mucinous tumors. Am J Surg Pathol 35:276e88Google Scholar
  3. 3.
    Khunamornpong S, Lerwill MF, Siriaunkgul S, Suprasert P, Pojchamarnwiputh S, Chiangmai WN, Young RH (2008) Carcinoma of extrahepatic bile ducts and gallbladder metastatic to ovary. A report of 16 cases. Int J Gynecol Pathol 27:366–379CrossRefGoogle Scholar
  4. 4.
    Ayhan A, Guney I, Saygan-Karamursel B, Taskiran C (2001) Ovarian metastasis of primary biliary and gallbladder carcinomas. Eur J Gynaecol Oncol 22:377–378PubMedGoogle Scholar
  5. 5.
    Jain V, Gupta K, Kudva R, Rodrigues GS (2006) A case of ovarian metastasis of gall bladder carcinoma simulating primary ovarian neoplasm: diagnostic pitfalls and review of literature. Int J Gynecol Cancer 16:319–321CrossRefGoogle Scholar
  6. 6.
    Jarvi K, Kelty CJ, Thomas WE, Gillespie A (2006) Bilateral ovarian metastases from carcinoma of the gallbladder. Gynecol Oncol 103:361–362CrossRefGoogle Scholar
  7. 7.
    Carlomagno C, Insabato L, Bifulco G, De Placido S, Lauria R (2010) Ovarian metastasis following gallbladder carcinoma: a case report. Eur J Gynaecol Oncol 31:219e21Google Scholar
  8. 8.
    Ricks AM, Han LY, Rashid A, Frumovitz M (2009) Gallbladder carcinoma presenting as a pelvic mass with elevated serum testosterone: a case report. J Reprod Med 54:259e60Google Scholar
  9. 9.
    Young RH, Scully RE (1990) Ovarian metastases from carcinoma of the gallbladder and extrahepatic bile ducts simulating primary tumors of the ovary. A report of six cases. Int J Gynecol Pathol 9:60–72CrossRefGoogle Scholar
  10. 10.
    Miyagui T, Luchemback L, Teixeira GH, Azevedo KM (2003) Meningeal carcinomatosis as the initial manifestation of a gallbladder adenocarcinoma associated with a Krukenberg tumor. Rev Hosp Clin Fac Med Sao Paulo 58:169–172CrossRefGoogle Scholar
  11. 11.
    Taranto AJ, Lourie R, Lau WF (2006) Ovarian vascular pedicle sign in ovarian metastasis arising from gall bladder carcinoma. Australas Radiol 50:504–506CrossRefGoogle Scholar
  12. 12.
    Kumar Y, Chahal A, Garg M, Bhutani A (2010) Occult gallbladder carcinoma presenting as a primary ovarian tumor in two women: two case reports and a review of the literature. J Med Case Rep 4:202CrossRefGoogle Scholar
  13. 13.
    Sun HD, Tsai CC, Hsiao SM, Wei MC, Wang KC (2012) Primary gallbladder carcinoma presenting as advanced-stage ovarian cancer. Taiwan J Obstet Gynecol 51:443e445Google Scholar
  14. 14.
    Albores-Saavedra J (1986) Atlas of tumor pathology (second series). Armed Forces Institute of Pathology, WashingtonGoogle Scholar
  15. 15.
    What are the key statistics about gallbladder cancer?. American Cancer Society. Available at http://wwwcancerorg/cancer/gallbladdercancer/detailedguide/gallbladder-key-statistics Accessed: Feb 21, 2017
  16. 16.
    Lowenfels AB, Maisonneuve P, Boyle P, Zatonski WA (1999) Epidemiology of gallbladder cancer. Hepatogastroenterology 46(27):1529–1532PubMedGoogle Scholar
  17. 17.
    Majumdar K, Singh DK, Kaur S, Rastogi A, Gondal R (2008) Papillary adenocarcinoma gallbladder with simultaneously detected bilateral ovarian metastasis: a case report. Internet J Gynecol Obst 9:1Google Scholar
  18. 18.
    Kanthan R, Senger JL, Kanthan S (2012) The multifaceted granulosa cell tumours—myths and realities: a review. ISRN Obstet Gynaecol 878635:1–12Google Scholar
  19. 19.
    Hart WR (2005) Diagnostic challenge of secondary (metastatic) ovarian tumors simulating primary endometrioid and mucinous neoplasm. Pathol Int 55:231CrossRefGoogle Scholar
  20. 20.
    Horng HC, Wang PH (2012) Ovarian cancer presenting as an acute abdomen was successfully diagnosed and managed by laparoscopy. Taiwan J Obstet Gynecol 51:146e7Google Scholar
  21. 21.
    Shih CY, Lai CR, Huang CY, Twu NF, Chao KC, Wang PH (2012) A challenge in the management of a patient with ovarian cancer associated with extensive endometriosis. Taiwan J Obstet Gynecol 51:324e5CrossRefGoogle Scholar
  22. 22.
    Lee J, Park SH, Chang HM, Kim JS, Choi HJ, Lee MA et al (2012) Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 13:181e8Google Scholar

Copyright information

© Indian Association of Surgical Oncology 2018

Authors and Affiliations

  • Shipra Sonkusare
    • 1
  • S. Vishwanath
    • 2
  • Prabhneet Kaur
    • 1
  • Pujitha Murthi
    • 1
  • Krishnapriya
    • 1
  1. 1.Department of Obstetrics and GynaecologyK.S. Hegde Medical AcademyMangaloreIndia
  2. 2.Department of Surgical OncologyK.S. Hegde Medical AcademyMangaloreIndia

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