Indian Journal of Surgical Oncology

, Volume 9, Issue 4, pp 644–646 | Cite as

Sarcomatoid Carcinoma of Urinary Bladder: a Case Report

  • Garima DagaEmail author
  • Prashant Kerkar
Case Report


Sarcomatoid carcinoma is an extremely rare aggressive tumor variant comprising about 0.3% of all primary tumors of the urinary bladder and carries an overall dismal prognosis. Diagnosis is important and is sometimes difficult. Immunohistochemistry plays an important role in establishing diagnosis. We report a case with sarcomatoid variant of bladder urothelial carcinoma and review the pathologic features. A 65-year-old male on evaluation of long standing obstructive voiding symptoms and intermittent hematuria found to have a bladder mass. Magnetic resonance urography revealed a 35 × 45 mm mass at dome of urinary bladder with perivesical fat infiltration. He underwent transurethral resection and histopathology revealed pT1 high-grade malignant spindle cell tumor. He underwent radical cystoprostatectomy with bilateral extended pelvic lymphadenectomy with EPLND with ileal conduit urine diversion. Histopathology revealed high-grade muscle invasive spindle cell tumor. The diagnosis was uncertain and two differential diagnosis were kept, sarcomatoid carcinoma and pleomorphic sarcoma. Finally, IHC confirmed the final diagnosis of sarcomatoid carcinoma as it was positive for cytokeratin, CK – 8/18, GATA 3. All lymph nodes were negative for metastasis (pT2, N0, Mx). Recognition of the rare variants of the urinary bladder urothelial tumors is imperative as it is affects the overall management and hence prognosis. Immunohistochemistry plays a paramount role in establishing the diagnosis.


Bladder cancer Sarcomatoid variant Immunohistochemistry 


  1. 1.
    Mallik AU, Rahman MZ, Sarker MMR (2010) Sarcomatoid carcinoma of urinary bladder—a case report. Banglajol 4(1):28–29Google Scholar
  2. 2.
    Bansal A, Kumar N, Sharma SC (2013) Sarcomatoid variant of urothelial carcinoma of the urinary bladder. J Cancer Res Therapeutics 9(4):571–573CrossRefGoogle Scholar
  3. 3.
    Wang J, Gillaspie C, Kunadharaju R, Talmon GA, Enke C (2011) Sarcomatoid urothelial carcinoma: a single cancer center experience. World J Oncol 2(4):175–180PubMedPubMedCentralGoogle Scholar
  4. 4.
    Sanchez JEH, Figueira YR, Gonzalez RT, Lopez RM, Tejeda LMG (2014) Sarcomatoid carcinoma of the urinary bladder: a case report and review of the literature. J Med Cases 5(2):116–119Google Scholar
  5. 5.
    Mittal V, Rupala KK, Yadav R, Suryavanshi M (2017) Giant sarcomatoid carcinoma with osseous metaplasia from urinary bladder diverticulum. Indian J Surgical Oncology:1–4Google Scholar

Copyright information

© Indian Association of Surgical Oncology 2018

Authors and Affiliations

  1. 1.Department of Surgical OncologyBombay HospitalMumbaiIndia

Personalised recommendations