Indian Journal of Surgical Oncology

, Volume 6, Issue 1, pp 63–68 | Cite as

Borderline Resectable Pancreatic Cancer

  • Bhargava Mullapudi
  • Patrick J. Hawkes
  • Asish Patel
  • Chandrakanth Are
  • Subhasis MisraEmail author
Review Article


Borderline resectable pancreatic cancer (BRPC) is an evolving diagnostic entity that blurs the distinction between resectable and locally advanced pancreatic cancer (Varadhachary et al. Ann Surg Oncol 13:1035–1046, 2006). Until recently the management of this disease has been poorly defined; however, consensus guidelines have been developed regarding the proper management of this diagnostic entity. Recent studies have shown that if appropriately identified and treated, this subset of disease can have outcomes similar to pancreatic cancer that is defined as resectable (Laurence et al. J Gastrointest Surg 15:2059–2069, 2011). The aim of this review is to outline the current consensus on definitions, workup and management of BRPC, and also provide a summary of issues that require progress as defined by the International Study Group of Pancreatic Surgery (ISGPS).


Borderline Pancreatic cancer Pancreas Whipple Pancreaticoduodenectomy 


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Copyright information

© Indian Association of Surgical Oncology 2015

Authors and Affiliations

  • Bhargava Mullapudi
    • 1
  • Patrick J. Hawkes
    • 1
  • Asish Patel
    • 1
  • Chandrakanth Are
    • 1
  • Subhasis Misra
    • 2
    Email author
  1. 1.Department of SurgeryUniversity of Nebraska Medical CenterOmahaUSA
  2. 2.Department of SurgeryTexas Tech University Health Sciences CenterAmarilloUSA

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