Indian Journal of Surgical Oncology

, Volume 3, Issue 4, pp 348–359 | Cite as

Nutritional Status and Nutritional Support Before and After Pancreatectomy for Pancreatic Cancer and Chronic Pancreatitis

  • Vasiliki Th. Karagianni
  • Apostolos E. Papalois
  • John K. TriantafillidisEmail author
Review Article


Cachexia, malnutrition, significant weight loss, and reduction in food intake due to anorexia represent the most important pathophysiological consequences of pancreatic cancer. Pathophysiological consequences result also from pancreatectomy, the type and severity of which differ significantly and depend on the type of the operation performed. Nutritional intervention, either parenteral or enteral, needs to be seen as a method of support in pancreatic cancer patients aiming at the maintenance of the nutritional and functional status and the prevention or attenuation of cachexia. Oral nutrition could reduce complications while restoring quality of life. Enteral nutrition in the post-operative period could also reduce infective complications. The evidence for immune-enhanced feed in patients undergoing pancreaticoduodenectomy for pancreatic cancer is supported by the available clinical data. Nutritional support during the post-operative period on a cyclical basis is preferred because it is associated with low incidence of gastric stasis. Postoperative total parenteral nutrition is indicated only to those patients who are unable to be fed orally or enterally. Thus nutritional deficiency is a relatively widesoread and constant finding suggesting that we must optimise the nutritional status both before and after surgery.


Chronic pancreatitis Nutritional status Nutritional support Pancreatic cancer Pancreatectomy 


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Copyright information

© Indian Association of Surgical Oncology 2012

Authors and Affiliations

  • Vasiliki Th. Karagianni
    • 1
  • Apostolos E. Papalois
    • 2
  • John K. Triantafillidis
    • 1
    • 3
    Email author
  1. 1.Department of Gastroenterology - Center for Inflammatory Bowel Disease“Saint Panteleimon” General HospitalNikaiaGreece
  2. 2.Experimental-Research CenterELPEN PharmaceuticalsPikermiGreece
  3. 3.HaidariGreece

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