Journal of Cancer Education

, Volume 31, Issue 1, pp 187–190 | Cite as

HPV Vaccine Awareness and Knowledge Among Women Living with HIV

  • L. T. Wigfall
  • S. A. Bynum
  • H. M. Brandt
  • J. R. Hébert


Cervical cancer risk is increased among women living with HIV (WLH). Human papillomavirus (HPV) vaccination has been shown to be safe and immunogenic among WLH. We examined HPV vaccine awareness and HPV knowledge among WLH. This cross-sectional study collected data from 145 WLH between March 2011 and April 2012. An interviewer-administered survey assessed HPV vaccine awareness and knowledge. Stata/IC 13 was used to perform chi-square tests and multivariate logistic regression analyses. Our sample was 90 % non-Hispanic black and 64 % earned <$10,000/year. Few (38 %) had heard of the HPV vaccine. Half (50 %) knew that HPV caused cervical cancer. HPV vaccine awareness was ten times higher among WLH who knew HPV caused cervical cancer (OR = 10.17; 95 % CI 3.82–27.06). HPV vaccine awareness is low among WLH. Cancer prevention efforts aimed at raising awareness about the HPV vaccine and increasing knowledge about HPV are necessary first steps in reducing cervical cancer disparities among WLH.


Awareness Cervical cancer HIV-positive HPV vaccine Knowledge 


  1. 1.
    Chin-Hong PV, Palefsky JM (2002) Natural history and clinical management of anal human papillomavirus disease in men and women infected with human immunodeficiency virus. Clin Infect Dis: Off Publ Infect Dis Soc Am 35(9):1127–1134CrossRefGoogle Scholar
  2. 2.
    Sun XW, Kuhn L, Ellerbrock TV, Chiasson MA, Bush TJ, Wright TC Jr (1997) Human papillomavirus infection in women infected with the human immunodeficiency virus. N Engl J Med 337(19):1343–1349CrossRefPubMedGoogle Scholar
  3. 3.
    Shiels MS, Pfeiffer RM, Gail MH, Hall HI, Li J, Chaturvedi AK et al (2011) Cancer burden in the HIV-infected population in the United States. J Natl Cancer Inst 103(9):753–762PubMedCentralCrossRefPubMedGoogle Scholar
  4. 4.
    Shiels MS, Pfeiffer RM, Hall HI, Li J, Goedert JJ, Morton LM et al (2011) Proportions of Kaposi sarcoma, selected non-Hodgkin lymphomas, and cervical cancer in the United States occurring in persons with AIDS, 1980-2007. JAMA: J Am Med Assoc 305(14):1450–1459CrossRefGoogle Scholar
  5. 5.
    Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM (2007) Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 370(9581):59–67CrossRefPubMedGoogle Scholar
  6. 6.
    Markowitz LE, Dunne EF, Saraiya M, Chesson HW, Curtis CR, Gee J et al (2014) Human papillomavirus vaccination: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep: Morb Mortal Wkly Rep Recomm Rep/ Centers Dis Control 63(RR-05):1–30Google Scholar
  7. 7.
    Kahn JA, Burk RD, Squires KE, Kapogiannis BG, Rudy B, Xu J et al (2012) Prevalence and risk factors for HPV in HIV-positive young women receiving their first HPV vaccination. J Acquir Immune Defic Syndr 61(3):390–399PubMedCentralCrossRefPubMedGoogle Scholar
  8. 8.
    Mills LA, Head KJ, Vanderpool RC (2013) HPV vaccination among young adult women: a perspective from Appalachian Kentucky. Prev Chron Dis 10:E17Google Scholar
  9. 9.
    Williams WW, Lu PJ, O’Halloran A, Bridges CB, Kim DK, Pilishvili T et al (2015) Vaccination coverage among adults, excluding influenza vaccination—United States, 2013. MMWR Morb Mortal Wkly Rep 64(4):95–102PubMedGoogle Scholar
  10. 10.
    NCI. Health Informatin National Trends Survey. Available at: Accessed 20 Oct 2015
  11. 11.
    Wigfall LT, Bynum SA, Brandt HM, Friedman DB, Bond SM, Lazenby GB, Richter DL, Glover SH, Hébert JR (2015) J Cancer Educ. doi:10.1007/s13187-014-0688-9
  12. 12.
    Bynum SA, Wigfall LT, Brandt HM, Richter DL, Glover SH, Hébert JR (2013) J Cancer Educ. doi:10.1007/s13187-013-0470-4

Copyright information

© American Association for Cancer Education 2015

Authors and Affiliations

  • L. T. Wigfall
    • 1
    • 2
  • S. A. Bynum
    • 3
  • H. M. Brandt
    • 2
    • 4
  • J. R. Hébert
    • 2
    • 5
  1. 1.Department of Health Services Policy and Management, Arnold School of Public HealthUniversity of South CarolinaColumbiaUSA
  2. 2.South Carolina Statewide Cancer Prevention and Control Program, Arnold School of Public HealthUniversity of South CarolinaColumbiaUSA
  3. 3.Department of Preventive Medicine and Biometrics, F. Edward Hébert School of MedicineUniformed Services University of the Health SciencesBethesdaUSA
  4. 4.Department of Health Promotion, Education, and Behavior, Arnold School of Public HealthUniversity of South CarolinaColumbiaUSA
  5. 5.Department of Epidemiology and Biostatistics, Arnold School of Public HealthUniversity of South CarolinaColumbiaUSA

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