Journal of Cancer Education

, Volume 28, Issue 2, pp 319–324

Prevalence, Risk Factors, and Disease Knowledge of Chronic Hepatitis B Infection in Vietnamese Americans in California

  • Nghi B. Ha
  • Huy N. Trinh
  • Trang T. Nguyen
  • Truong-Sinh Leduc
  • Christopher Bui
  • Nghiem B. Ha
  • Carrie R. Wong
  • Anh Thu Tran
  • Mindie H. Nguyen


Our goal is to examine the prevalence, risk factors, and disease knowledge of chronic hepatitis B (CHB) among Vietnamese Americans in California. We also examined treatment eligibility and linkage to care among patients who tested positive for CHB. We enrolled 717 subjects from ten different hepatitis B virus (HBV) screening events in five locations from January 2009 to June 2010 in California. HBV status was determined by hepatitis B surface antigen (HBsAg) and antibody. Data were collected by a 36-question survey. A total of 99 patients (13.8 %) had positive HBsAg, especially those aged 31–40 years (23.6 %), and 177 (24.7 %) were still susceptible to HBV infection. A significant proportion of those who were HBsAg positive or still susceptible reported a history of HBV vaccination (10 and 20 %, respectively). Following adjustments for age and sex, significant predictors for HBsAg positivity were lack of healthcare coverage (OR = 2.4, p = 0.004), having a family history of CHB (OR = 2.1, p = 0.009), and prior occupational exposure (OR = 3.0, p = 0.007). Of those who tested positive, 13.3 % met criteria for antiviral therapy, but none had been initiated on treatment. HBV prevalence in Vietnamese Americans in California was high (13.8 %), especially in those between 31 and 40 years of age. Patient disease and treatment knowledge was poor, as were follow-up and management of those found to have CHB and/or have indication for antiviral therapy.


Epidemiology Screening Asian HBV 


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Nghi B. Ha
    • 1
    • 2
  • Huy N. Trinh
    • 3
  • Trang T. Nguyen
    • 3
  • Truong-Sinh Leduc
    • 4
  • Christopher Bui
    • 5
  • Nghiem B. Ha
    • 6
    • 1
  • Carrie R. Wong
    • 7
    • 1
  • Anh Thu Tran
    • 3
  • Mindie H. Nguyen
    • 6
    • 8
  1. 1.Pacific Health FoundationSan JoseUSA
  2. 2.School of PharmacyUniversity of California San FranciscoSan FranciscoUSA
  3. 3.Song Manh, IncSan JoseUSA
  4. 4.Leduc Medical GroupFountain ValleyUSA
  5. 5.Christopher Duong Bui MD IncWestminsterUSA
  6. 6.Division of Gastroenterology and Hepatology, Department of MedicineStanford University Medical CenterStanfordUSA
  7. 7.Stony Brook University School of MedicineStony BrookUSA
  8. 8.Division of Gastroenterology and HepatologyStanford University Medical CenterPalo AltoUSA

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