Journal of Medical Toxicology

, Volume 12, Issue 2, pp 192–198 | Cite as

Case Files of the University of Massachusetts Toxicology Fellowship: Does This Smoke Inhalation Victim Require Treatment with Cyanide Antidote?

  • Eike HamadEmail author
  • Kavita Babu
  • Vikhyat S. Bebarta


Cyanide toxicity is common after significant smoke inhalation. Two cases are presented that provide framework for the discussion of epidemiology, pathogenesis, presenting signs and symptoms, and treatment options of inhalational cyanide poisoning. An evidence-based algorithm is proposed that utilizes point-of-care testing to help physicians identify patients who benefit most from antidotal therapy.


Cyanide Hydroxocobalamin Smoke inhalation Fire Sodium thiosulfate 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no competing interests.

Sources of Funding

There was no funding for this project.


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Copyright information

© American College of Medical Toxicology 2016

Authors and Affiliations

  • Eike Hamad
    • 1
    Email author
  • Kavita Babu
    • 2
  • Vikhyat S. Bebarta
    • 3
    • 4
    • 5
  1. 1.University of MassachusettsWorcesterUSA
  2. 2.Department of Emergency MedicineUniversity of MassachusettsWorcesterUSA
  3. 3.Department of Emergency Medicine and Medical ToxicologyUniversity of Colorado School of MedicineAuroraUSA
  4. 4.Department of PharmacologyUniversity of Colorado School of MedicineAuroraUSA
  5. 5.CBRNE Enhanced Response Force Package (CERFP)Colorado Air National Guard, Buckley AFBAuroraUSA

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