Journal of Medical Toxicology

, Volume 9, Issue 1, pp 71–74 | Cite as

Acute Kidney Injury Due to Intravenous Bleach Injection

  • Ashish Verma
  • Vijay K. Vanguri
  • Venkata Golla
  • Sean Rhyee
  • Matthew Trainor
  • Konstantin Abramov
Toxicology Observation



Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis.


We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.


Bleach Cardiac Dialysis Failure Kidney Sodium hypochlorite 


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Copyright information

© American College of Medical Toxicology 2012

Authors and Affiliations

  • Ashish Verma
    • 1
  • Vijay K. Vanguri
    • 2
  • Venkata Golla
    • 1
  • Sean Rhyee
    • 3
  • Matthew Trainor
    • 1
  • Konstantin Abramov
    • 1
  1. 1.Division of Renal MedicineUniversity of Massachusetts Medical SchoolWorcesterUSA
  2. 2.Department of PathologyUniversity of Massachusetts Medical SchoolWorcesterUSA
  3. 3.Department of Emergency Medicine and ToxicologyUniversity of Massachusetts Medical SchoolWorcesterUSA

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