Translational Behavioral Medicine

, Volume 1, Issue 2, pp 327–330

The many faces of translational research: a tale of two studies

  • Stephen M Weiss
  • Deborah L Jones
  • Maria Lopez
  • Olga Villar-Loubet
  • Ndashi Chitalu
Article

ABSTRACT

Translational research can take many forms: bench to bedside, across cultural groups, across geographical boundaries, among others. This case study will share how we addressed all three “translational” issues using two evidence-based studies (USA, Zambia) to illustrate these “roads less traveled.” Our implementation and dissemination efforts were anchored by the “train the trainer” strategy, and the Glasgow RE-AIM model provided programmatic guideposts and direction. Keeping all stakeholders (scientific, community, political) involved in the implementation and dissemination process was an essential, perhaps determining factor in the success of the translation process.

KEYWORDS

HIV prevention Sexual risk reduction Training of trainers RE-AIM Translational research Women and couples living with HIV 

References

  1. 1.
    Brimmer, D. J., McCleary, K. K., Lupton, T. A., Faryna, K. M., & Hynes Reeves, W. C. (2008). A train-the-trainer education and promotion program: chronic fatigue syndrome—a diagnostic and management challenge. BMC Medical Education, 8, 49.PubMedCrossRefGoogle Scholar
  2. 2.
    Glasgow, E. R., Lichtenstein, E., & Marcus, A. C. (1993). Why don’t we see more translation of health promotion research to practice? Rethinking the efficacy-to-effectiveness translation. American Journal of Public Health, 93, 1261–1267.CrossRefGoogle Scholar
  3. 3.
    Ironson, G., Weiss, S., Lydston, D. D., Lechner, S., Ishii, M., Asthana, D., et al. (2005). The impact of improved self-efficacy on HIV viral load and distress in culturally diverse women living with AIDS. AIDS Care, 17(2), 222–236.PubMedCrossRefGoogle Scholar
  4. 4.
    Jones, D., Weiss, S. M., Malow, R. M., Ishii, M., Devieux, J., Stanley, H., et al. (2001). A brief sexual barrier intervention for women living with AIDS: acceptability, use and ethnicity. Journal of Urban Health, 78, 593–604.PubMedGoogle Scholar
  5. 5.
    Jones, D. L., Ishii, M., LaPerriere, A., Stanley, H., Antoni, M., Ironson, G., et al. (2003). Influencing medication adherence among women with AIDS. AIDS Care, 15, 463–475.PubMedCrossRefGoogle Scholar
  6. 6.
    Jones, D. L., Weiss, S. M., Bhat, G. J., Feldman, D. A., Bwalya, V., & Budash, D. (2004). A sexual barrier intervention for HIV+/− Zambian women: acceptability and use of vaginal chemical barriers. Journal of Multicultural Nursing and Health, 10, 27–31.Google Scholar
  7. 7.
    Jones, D., Owen, M. I., Lydston, D., Tobin, J. N., Brondolo, E., & Weiss, S. (2010a). Self efficacy and distress in women with AIDS: The SMART/EST women’s project. AIDS Care, 14, 1–10.Google Scholar
  8. 8.
    Jones, D., Villar-Loubet, O. M., Kankasa, C., Chitalu, N., Mumbi, M., & Weiss, S. (2010b). Contraception and family planning among HIV seroconcordant and serodiscordant couples in the US and Zambia. Open Access Journal of Contraception, 1, 23–34.CrossRefGoogle Scholar
  9. 9.
    Jones, D. L., Weiss, S. M., Chitalu, N., Mumbi, M., Vamos, S., Villar-Loubet, O., et al. (2009). Sexual risk reduction among Zambian couples. SAHARA, 6, 69–75.Google Scholar
  10. 10.
    Jones, D. L., Weiss, S. M., Chitalu, N., Mumbi, M., Shine, A., Vamos, S., et al. (2008). Acceptability and use of sexual barrier products and lubricants among HIV seropositive Zambian men. AIDS Patient Care and STDs, 22, 1015–1020.PubMedCrossRefGoogle Scholar
  11. 11.
    Jones, D. L., Weiss, S. M., Chitalu, N., Bwalya, V., & Villar, O. (2008). Acceptability of microbicidal surrogates among Zambian women. Sexually Transmitted Diseases, 35, 147–153.PubMedCrossRefGoogle Scholar
  12. 12.
    Jones, D. L., Weiss, S. M., Waldrop-Valverde, D., Chitalu, N., Mumbi, M., & Vamos, S. (2008). Community-based risk reduction in Zambia. Open Health Services and Policy Journal, 1, 38–44.CrossRefGoogle Scholar
  13. 13.
    Jones, D. L., Weiss, S. M., Chitalu, N., Kumar, M., Villar, O., Bwalya, V., et al. (2007). Sexual risk intervention in multiethnic drug and alcohol users. American Journal of Infectious Diseases, 3, 169–176.PubMedCrossRefGoogle Scholar
  14. 14.
    Jones, D., MacPherson-Baker, S., Lydston, D., Gousse, Y., Brondolo, E., Camille, J., et al. (2007b). Influencing medication adherence among HIV+ women: the SMART/EST II Women’s Project. AIDS & Behavior, 11, 79–86.CrossRefGoogle Scholar
  15. 15.
    Jones, D. L., Bhat, G. J., Weiss, S. M., Feldman, D. A., & Bwalya, V. (2006). Influencing sexual practices among HIV positive Zambian women. AIDS Care, 18, 629–635.PubMedCrossRefGoogle Scholar
  16. 16.
    Jones, D., Ross, D., Weiss, S. M., Bhat, G., & Chitalu, N. (2005). Influence of partner participation on sexual risk behavior reduction among HIV-positive Zambian women. Journal of Urban Health, 82, 92–100.Google Scholar
  17. 17.
    Kelly, J. A., Somlai, A. M., DiFrancisco, W. J., et al. (2002). Bridging the gap between the science and the service of HIV prevention: transferring effective research-based HIV prevention interventions to community AIDS service providers. American Journal of Public Health, 90, 1082–1088.CrossRefGoogle Scholar
  18. 18.
    LaPerriere, A., Ironson, G., Antoni, M. H., Stanley, H., Jones, D., Ishii, M., et al. (2005). Decreased depression up to one year following CBSM+ intervention in depressed women with AIDS: the Smart/EST Women’s Project. Journal Health Psychology, 10, 223–231.CrossRefGoogle Scholar
  19. 19.
    Lechner, S. C., Antoni, M. H., Lydston, D., LaPerriere, A., Ishii, M., Devieux, J., et al. (2003). Cognitive-behavioral interventions improve quality of life in women with AIDS. Journal of Psychosomatic Research, 54, 253–261.PubMedCrossRefGoogle Scholar
  20. 20.
    Lopez, E. J., Jones, D. L., Villar-Loubet, O. M., Arheart, K., & Weiss, S. M. (2010). Violence, coping and consistent medication adherence in HIV-positive couples. AIDS Education and Prevention, 22, 63–70.CrossRefGoogle Scholar
  21. 21.
    Lopez, E., Jones, D., Ishii, M., Tobin, J. N., & Weiss, S. M. (2007). HIV medication adherence and substance use: the SMART/EST women’s project. American Journal of Infectious Diseases, 3, 239–246.Google Scholar
  22. 22.
    Segal-Isaacson, C. J., Tobin, J. N., Weiss, S. M., Brondolo, E., Vaughn, A., Wang, C., et al. (2006). Improving dietary habits in disadvantaged women with HIV/AIDS: the SMART/EST women’s project. AIDS and Behavior, 10(6), 659–670.PubMedCrossRefGoogle Scholar
  23. 23.
    Spiegel, D., Butler, L. D., Giese-Davis, J., Koopman, C., Miller, E., DiMiceli, S., et al. (2007). Effects of supportive-expressive group therapy on survival of patients with metastatic breast cancer: a randomized prospective trial. Cancer, 110(5), 1130–1138.PubMedCrossRefGoogle Scholar
  24. 24.
    Weiss, S., Tobin, J. N., Antoni, M., Ironson, G., Ishii, M., Vaughn, A., et al. (2011). Enhancing the health of women living with HIV: the SMART/EST Women’s Project. International Journal of Women’s Health, 3, 63–77.PubMedGoogle Scholar

Copyright information

© Society of Behavioral Medicine 2011

Authors and Affiliations

  • Stephen M Weiss
    • 1
  • Deborah L Jones
    • 1
  • Maria Lopez
    • 1
  • Olga Villar-Loubet
    • 1
  • Ndashi Chitalu
    • 2
  1. 1.Department of Psychiatry and Behavioral SciencesUniversity of Miami Miller School of MedicineMiamiUSA
  2. 2.University of Zambia School of MedicineLusakaZambia

Personalised recommendations