Perspectives in TSPO PET Imaging for Neurologic Diseases
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The translocator protein (18 kDa) (TSPO) is a mitochondrial transmembrane protein, which has brought attention as a neuroinflammatory biomarker. Positron emission tomography (PET) imaging studies have been done for several decades, since neuroinflammation has been implicated as an important pathophysiology of several common neurologic disorders. However, despite numerous previous studies with positive findings, its clinical significance is not yet clear. Various attempts to overcome the limitations are ongoing, in order to bring acceptance for use in clinics.
KeywordsNeuroinflammation Neurologic disease Positron emission tomography Translocator protein (18 kDa)
This work was supported by a grant from the Basic Science Research Program through the National Research Foundation of Korea (NRF) (grant no. 2016R1D1A1A02937028).
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Conflict of Interest
This work was supported by a grant from the Basic Science Research Program through the National Research Foundation of Korea (NRF) (no. 2016R1D1A1A02937028).
This article does not contain any studies with human participants or animals performed by the author.
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