Nuclear Medicine and Molecular Imaging

, Volume 53, Issue 6, pp 382–385 | Cite as

Perspectives in TSPO PET Imaging for Neurologic Diseases

  • Yoo Sung SongEmail author


The translocator protein (18 kDa) (TSPO) is a mitochondrial transmembrane protein, which has brought attention as a neuroinflammatory biomarker. Positron emission tomography (PET) imaging studies have been done for several decades, since neuroinflammation has been implicated as an important pathophysiology of several common neurologic disorders. However, despite numerous previous studies with positive findings, its clinical significance is not yet clear. Various attempts to overcome the limitations are ongoing, in order to bring acceptance for use in clinics.


Neuroinflammation Neurologic disease Positron emission tomography Translocator protein (18 kDa) 


Funding Information

This work was supported by a grant from the Basic Science Research Program through the National Research Foundation of Korea (NRF) (grant no. 2016R1D1A1A02937028).

Compliance With Ethical Standards

Conflict of Interest

This work was supported by a grant from the Basic Science Research Program through the National Research Foundation of Korea (NRF) (no. 2016R1D1A1A02937028).

Ethical Approval

This article does not contain any studies with human participants or animals performed by the author.

Informed consent

Not applicable.


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Copyright information

© Korean Society of Nuclear Medicine 2019

Authors and Affiliations

  1. 1.Seoul National University Bundang HospitalSeongnamSouth Korea

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