Gastrointestinal stromal tumour of the jejunum in an elderly female patient with atypical symptomatology
Case Report
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Abstract
Gastrointestinal stromal tumour (GIST) neoplasms are rare malignancies of the gastrointestinal tract. Most commonly they present with gastrointestinal bleeding and abdominal pain as the main symptoms. Here we present the case of a 52-year-old Greek female patient with GIST neoplasm of the jejunum, who attended the Emergency Department of our Hospital with indigestion and abdominal distention as the only symptoms. This is, to our knowledge, the second GIST tumour of the jejunum ever reported in Greece and the first with atypical symptomatology.
Key words
GIST jejunum CD117 imatinibPreview
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References
- 1.Mazur MT, Clark HB. Gastric stromal tumours: Reappraisal of histogenesis. Am J Surg Pathol 1983;7:507–19.CrossRefPubMedGoogle Scholar
- 2.Suryawanshi KH, Patil TB, Damle RP, Dravid NV, Surana A. Gastrointestinal Stromal Tumour of Small Intestine Presenting as a Mesenteric Mass. JCDR 2014;8:FD14–FD16.PubMedPubMedCentralGoogle Scholar
- 3.Sato K, Tanaka T, Kato N, Ishii T, Terao T, Yuichi Murayama Y. Metastatic Cerebellar Gastrointestinal Stromal Tumour with Obstructive Hydrocephalus Arising from the Small Intestine: A Case Report and Review of the Literature. Case Rep Oncol Med 2014; doi: 10.1155/2014/343178.Google Scholar
- 4.Poveda A, del Muro XG, López-Guerrero JA, et al. GEIS 2013 guidelines for gastrointestinal sarcomas (GIST). Cancer Chemother Pharmacol. 2014;74:883–98.CrossRefPubMedPubMedCentralGoogle Scholar
- 5.Dimitroulopoulos D, Fotopoulou A, Xinopoulos D, et al. Synchronous occurrence of colorectal adenocarcinoma and colonic gastrointestinal stromal tumour (GIST). A case report. Annals of Gastroenterology 2009;22:197–200.Google Scholar
- 6.Gourgiotis S, Kotoulas D, Aloizos S, Kolovou A, Salemis NS, Kantounakis I. Preoperative diagnosis of obscure gastrointestinal bleeding due to a GIST of the jejunum: a case report. Cases J 2009; doi: 10.4076/1757-1626-2-8186.Google Scholar
- 7.Nishida T, Hirota S, Taniguchi M, et al. Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet 1998;19:323–4.CrossRefPubMedGoogle Scholar
- 8.Hirota S, Nishida T, Isozaki K, et al. Familial gastrointestinal stromal tumours associated with dysphagia and novel type germline mutation of KIT gene. Gastroenterology 2002;122:1493–9.CrossRefPubMedGoogle Scholar
- 9.Tan CB, Zhi W, Shahzad G, Mustacchia P. Gastrointestinal Stromal Tumours: A Review of Case Reports, Diagnosis, Treatment, and Future Directions. International Scholarly Research Network ISRN Gastroenterology 2012; doi: 10.5402/2012/595968Google Scholar
- 10.Sakai M, Wada W, Kimura S, et al. Single-Incision Laparoscopic Surgery for a Small-Intestinal Gastrointestinal Stromal Tumour: Report of a Case. Int Surg 2014;99:463–6.CrossRefPubMedPubMedCentralGoogle Scholar
- 11.Abirami Krithiga J, Jeyakumar S, Jaivinod Kumar R, Tharun C. Small bowel GIST: Case reports and review of literature. J Evolution Med Dent Sci 2014;3:11601–7.CrossRefGoogle Scholar
- 12.Roy SD, Khan D, De KK, De U. Spontaneous perforation of jejunal gastrointestinal stromal tumour (gist). Case report and review of literature. WJES 2012;7:37.PubMedPubMedCentralGoogle Scholar
- 13.Memmi N, Cipe G, Bektasoglu H, et al. Perforated gastrointestinal stromal tumour in the jejunum: A rare cause of acute abdomen. Oncology Letters 2012;4:1244–6.PubMedPubMedCentralGoogle Scholar
- 14.Jaison J, Joshi SR, Pathak S, Tekwani D, Nagare M. Gastrointestinal stromal tumour at an unusual site-jejunum: A case report. International Journal of Scientific Study 2014;2:80–3.Google Scholar
- 15.Padasali PS, Govindaraj E, Somasekhar K. A case of gastrointestinal bleeding secondary to a small bowel gastrointestinal stromal tumour before causing hemoperitoneum. Oncology, Gastroenterology and Hepatology Reports 2015;4:49–51.CrossRefGoogle Scholar
- 16.Madhivanan K, Arunagiri V, Nanda Kishore M, Bhawana Ashok B, Srinivasan K. Intratumoural bleed in small bowel GIST mimicking peritonitis: An unusual presentation. GCR 2011;4:137–40.Google Scholar
- 17.Misawa S, Takeda M, Sakamoto H, Kirii Y, Ota H, Takagi H. Spontaneous rapture of a giant gastrointestinal tumour of the jejunum: a case report and literature review. WJSO 2014;12:153.Google Scholar
- 18.Alessiani M, Gianola M, Rossi S, et al. Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review. International Journal of Surgery Case Reports 2015;6:58–62.CrossRefGoogle Scholar
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© Hellenic Surgical Society and Springer-Verlag GmbH Austria 2017