Translational Stroke Research

, Volume 7, Issue 4, pp 343–353 | Cite as

Academic-industry Collaborations in Translational Stroke Research

  • Johannes Boltze
  • Daniel-Christoph Wagner
  • Henryk Barthel
  • Matthew J. Gounis
SI: Challenges and Controversies in Translational Stroke Research


Academic-industry collaborations are an emerging format of translational stroke research. Next to classic contract research models, a multitude of collaboration models has been developed, some of which even allowing for multinational or intercontinental research programs. This development has recently been paralleled by first successful attempts to overcome the translational stroke research road block, such as the unprecedented success of novel endovascular approaches or the advent of the multicenter preclinical trial concept. While the first underlines the role of the industry as a major innovation driver in stroke research, the latter will require enrollment of industrial partners for optimal output. Moreover, academic-industry partnerships are invaluable to bridge the translational “valley of death” as well as funding gaps in times of dwindling public funding and declining high risk capital investments. However, these collaborations are also subject to relevant challenges because interests, values, and aims often significantly differ between cademia and industry. Here, we describe common academic-industry collaboration models as well as associated benefits and challenges in the stroke research arena. We also suggest strategies for improved planning, implementation, guidance, and utilization of academic-industry collaborations to the maximum mutual benefit.


Academic-industry collaboration Stroke research Translational research Research alliances 



We thank Professor Charli Kruse for providing input and valuable perspectives on academic-industry collaborations. Illustrative elements in Figure 1 were either taken from inhouse material or purchased from the fotolia webpage (rodent pictures only,

Author contribution

JB, DCW, and MJG wrote the manuscript. All authors corrected and improved the draft, and approved the final manuscript version.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.


Only institutional funds were used for this project.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Johannes Boltze
    • 1
    • 2
  • Daniel-Christoph Wagner
    • 2
  • Henryk Barthel
    • 3
  • Matthew J. Gounis
    • 4
  1. 1.Fraunhofer Research Institution for Marine Biotechnology and Institute for Medical and Marine BiotechnologyUniversity of LübeckLübeckGermany
  2. 2.Fraunhofer Institute for Cell Therapy and ImmunologyLeipzigGermany
  3. 3.Department of Nuclear MedicineUniversity of LeipzigLeipzigGermany
  4. 4.New England Center for Stroke Research, Department of RadiologyUniversity of Massachusetts Medical SchoolWorcesterUSA

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