An Update on Inflammation in the Acute Phase of Intracerebral Hemorrhage
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Intracerebral hemorrhage (ICH) is a common and severe neurological disorder, which is associated with high rates of mortality and morbidity. Despite extensive research into the pathology of ICH, there are still no clinically approved neuroprotective treatments. Currently, increasing evidence has shown that inflammatory responses participate in the pathophysiological processes of brain injury following ICH. In this editorial, we summarized some promising advances in the field of inflammation and ICH, which contained animal and human investigations; discussed the role of neuroinflammation, systemic inflammatory responses, and some potential targets; and focused on the challenges of translation between pre-clinical and clinical studies and potential anti-inflammatory therapeutic approaches after ICH.
KeywordsIntracerebral hemorrhage Inflammation Brain injury
Compliance with Ethics Requirements
The study was approved by the Ethics Committee of the First Affiliated Hospital of Soochow University. This article does not contain any studies with human or animal subjects.
Conflict of Interest
Sheng Chen declares that he has no conflict of interest. Qingwu Yang declares that he has no conflict of interest. Gang Chen declares that he has no conflict of interest. John H. Zhang declares that he has no conflict of interest.
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