Translational Stroke Research

, Volume 3, Issue 2, pp 178–181 | Cite as

Clinical Implications of Neuroimaging in Stroke

  • Joffre E. Olaya
  • Joseph R. Keen
  • Frank P. K. Hsu
Commentaries
First Online:
Received:
Accepted:
  • 99 Downloads

Keywords

Ischemic Stroke Hemorrhagic Stroke Cerebral Blood Volume Mean Transit Time Decompressive Craniectomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

References

  1. 1.
    Broderick J, Connolly S, Feldmann E, Hanley D, Kase C, Krieger D, et al. Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group. Stroke. 2007;38:2001–23.PubMedCrossRefGoogle Scholar
  2. 2.
    Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT, et al. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet. 2005;365:387–97.PubMedGoogle Scholar
  3. 3.
    Saini M, Butcher K. Advanced imaging in acute stroke management—part I: computed tomographic. Neurol India. 2009;57:541–9.PubMedCrossRefGoogle Scholar
  4. 4.
    Kasner SE, Demchuk AM, Berrouschot J, Schmutzhard E, Harms L, Verro P, et al. Predictors of fatal brain edema in massive hemispheric ischemic stroke. Stroke. 2001;32:2117–23.PubMedCrossRefGoogle Scholar
  5. 5.
    Vahedi K, Vicaut E, Mateo J, Kurtz A, Orabi M, Guichard JP, et al. Sequential-design, multicenter, randomized, controlled trial of early decompressive craniectomy in malignant middle cerebral artery infarction (DECIMAL trial). Stroke. 2007;38:2506–17.PubMedCrossRefGoogle Scholar
  6. 6.
    Juttler E, Schwab S, Schmiedek P, Unterberg A, Hennerici M, Woitzik J, et al. Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY): a randomized, controlled trial. Stroke. 2007;38:2518–25.PubMedCrossRefGoogle Scholar
  7. 7.
    Hofmeijer J, Kappelle LJ, Algra A, Amelink GJ, van Gijn J, van der Worp HB. Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy after Middle Cerebral Artery Infarction with Life-Threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial. Lancet Neurol. 2009;8:326–33.PubMedCrossRefGoogle Scholar
  8. 8.
    Vahedi K, Hofmeijer J, Juettler E, Vicaut E, George B, Algra A, et al. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol. 2007;6:215–22.PubMedCrossRefGoogle Scholar
  9. 9.
    Juttler E, Bosel J, Amiri H, Schiller P, Limprecht R, Hacke W, et al. DESTINY II: decompressive surgery for the treatment of malignant infarction of the middle cerebral artery II. Int J Stroke. 2011;6:79–86.PubMedCrossRefGoogle Scholar
  10. 10.
    Duffis EJ, Al-Qudah Z, Prestigiacomo CJ, Gandhi C. Advanced neuroimaging in acute ischemic stroke: extending the time window for treatment. Neurosurg Focus. 2011;30:E5.PubMedCrossRefGoogle Scholar
  11. 11.
    Kleindorfer D, Lindsell CJ, Brass L, Koroshetz W, Broderick JP. National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate. Stroke. 2008;39:924–8.PubMedCrossRefGoogle Scholar
  12. 12.
    National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581–7.CrossRefGoogle Scholar
  13. 13.
    Hacke W, Kaste M, Bluhmki E, Brozman M, Davalos A, Guidetti D, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359:1317–29.PubMedCrossRefGoogle Scholar
  14. 14.
    Astrup J, Siesjo BK, Symon L. Thresholds in cerebral ischemia—the ischemic penumbra. Stroke. 1981;12:723–5.PubMedCrossRefGoogle Scholar
  15. 15.
    Heiss WD. Experimental evidence of ischemic thresholds and functional recovery. Stroke. 1992;23:1668–72.PubMedCrossRefGoogle Scholar
  16. 16.
    Konstas AA, Goldmakher GV, Lee TY, Lev MH. Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 2: technical implementations. AJNR Am J Neuroradiol. 2009;30:885–92.PubMedCrossRefGoogle Scholar
  17. 17.
    Wintermark M, Fischbein NJ, Smith WS, Ko NU, Quist M, Dillon WP. Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke. AJNR Am J Neuroradiol. 2005;26:104–12.PubMedGoogle Scholar
  18. 18.
    Schramm P, Schellinger PD, Fiebach JB, Heiland S, Jansen O, Knauth M, et al. Comparison of CT and CT angiography source images with diffusion-weighted imaging in patients with acute stroke within 6 hours after onset. Stroke. 2002;33:2426–32.PubMedCrossRefGoogle Scholar
  19. 19.
    Schramm P, Schellinger PD, Klotz E, Kallenberg K, Fiebach JB, Kulkens S, et al. Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration. Stroke. 2004;35:1652–8.PubMedCrossRefGoogle Scholar
  20. 20.
    Wada R, Aviv RI, Fox AJ, Sahlas DJ, Gladstone DJ, Tomlinson G, et al. CT angiography “spot sign” predicts hematoma expansion in acute intracerebral hemorrhage. Stroke. 2007;38:1257–62.PubMedCrossRefGoogle Scholar
  21. 21.
    Delgado Almandoz JE, Yoo AJ, Stone MJ, Schaefer PW, Oleinik A, Brouwers HB, et al. The spot sign score in primary intracerebral hemorrhage identifies patients at highest risk of in-hospital mortality and poor outcome among survivors. Stroke. 2010;41:54–60.PubMedCrossRefGoogle Scholar
  22. 22.
    Hjort N, Christensen S, Solling C, Ashkanian M, Wu O, Rohl L, et al. Ischemic injury detected by diffusion imaging 11 minutes after stroke. Ann Neurol. 2005;58:462–5.PubMedCrossRefGoogle Scholar
  23. 23.
    Saini M, Butcher K. Advanced imaging in acute stroke management—part II: magnetic resonance imaging. Neurol India. 2009;57:550–8.PubMedCrossRefGoogle Scholar
  24. 24.
    Kidwell CS, Alger JR, Saver JL. Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging. Stroke. 2003;34:2729–35.PubMedCrossRefGoogle Scholar
  25. 25.
    Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol. 2008;7:299–309.PubMedCrossRefGoogle Scholar
  26. 26.
    Albers GW, Thijs VN, Wechsler L, Kemp S, Schlaug G, Skalabrin E, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol. 2006;60:508–17.PubMedCrossRefGoogle Scholar
  27. 27.
    Jiang Q, Zhang ZG, Chopp M. MRI evaluation of white matter recovery after brain injury. Stroke. 2010;41:S112–3.PubMedCrossRefGoogle Scholar
  28. 28.
    Watanabe T, Honda Y, Fujii Y, Koyama M, Matsuzawa H, Tanaka R. Three-dimensional anisotropy contrast magnetic resonance axonography to predict the prognosis for motor function in patients suffering from stroke. J Neurosurg. 2001;94:955–60.PubMedCrossRefGoogle Scholar
  29. 29.
    Karaszewski B, Thomas RG, Chappell FM, Armitage PA, Carpenter TK, Lymer GK, et al. Brain choline concentration. Early quantitative marker of ischemia and infarct expansion? Neurology. 2010;75:850–6.PubMedCrossRefGoogle Scholar
  30. 30.
    Weinstein PR, Hong S, Sharp FR. Molecular identification of the ischemic penumbra. Stroke. 2004;35:2666–70.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Joffre E. Olaya
    • 1
  • Joseph R. Keen
    • 1
  • Frank P. K. Hsu
    • 1
  1. 1.Department of NeurosurgeryLoma Linda University Medical CenterLoma LindaUSA

Personalised recommendations