Pre-procedural combined coronary angiography and stress myocardial perfusion imaging using 320-detector CT in unprotected left main and ostial left anterior descending artery intervention

  • Brian S. Ko
  • Marcus Crossett
  • Sujith K. Seneviratne
Case Report
  • 96 Downloads

Abstract

Pre-procedural anatomic and functional coronary assessment plays a crucial role in selection of patients suitable for unprotected left main percutaneous coronary intervention. Combined coronary computed tomography angiography and adenosine stress computed tomography myocardial perfusion imaging is a non-invasive technique which may provide this information. This is the first report describing its use to assist patient selection and procedural planning prior to elective left main and ostial left anterior descending artery coronary intervention.

Keywords

Myocardial ischemia Complex percutaneous coronary intervention Fractional flow reserve 

Abbreviations

LM

Left main coronary artery

FFR

Fractional flow reserve

CCTA

CT coronary angiography

CTP

CT stress myocardial perfusion imaging

LAD

Left anterior descending artery

LCx

Left circumflex coronary artery

RCA

Right coronary artery

PCI

Percutaneous coronary intervention

References

  1. 1.
    Taylor HA, Deumite NJ, Chaitman BR, Davis KB, Killip T, Rogers WJ. Asymptomatic left main coronary artery disease in the Coronary Artery Surgery Study (CASS) registry. Circulation. 1989;79:1171–9.PubMedCrossRefGoogle Scholar
  2. 2.
    Dragu R, Kerner A, Gruberg L, et al. Angiographically uncertain left main coronary artery narrowings: correlation with multidetector computed tomography and intravascular ultrasound. Int J Cardiovasc Imaging. 2008;24:557–63.PubMedCrossRefGoogle Scholar
  3. 3.
    Rochitte CE, George RT, Chen MY, et al. Computed tomography angiography and perfusion to assess coronary artery stenosis causing perfusion defects by single photon emission computed tomography: the CORE320 study. Eur Heart J 2013: Epub Ahead of print 21/11/2013.Google Scholar
  4. 4.
    Ko BS, Cameron JD, Meredith IT, et al. Computed tomography stress myocardial perfusion imaging in patients considered for revascularization: a comparison with fractional flow reserve. Eur Heart J. 2012;33:67–77.PubMedCrossRefGoogle Scholar
  5. 5.
    Ko BS, Cameron JD, Leung M, et al. Combined CT coronary angiography and stress myocardial perfusion imaging for hemodynamically significant stenoses in patients with suspected coronary artery disease: a comparison with fractional flow reserve. JACC Cardiovasc Imaging. 2012;5:1097–111.PubMedCrossRefGoogle Scholar
  6. 6.
    Bamberg F, Becker A, Schwarz F, et al. Detection of hemodynamically significant coronary artery stenosis: incremental diagnostic value of dynamic CT-based myocardial perfusion imaging. Radiology. 2011;260:689–98.PubMedCrossRefGoogle Scholar
  7. 7.
    Bettencourt N, Chiribiri A, Schuster A, et al. Direct comparison of cardiac magnetic resonance and multidetector computed tomography stress-rest perfusion imaging for detection of coronary artery disease. J Am Coll Cardiol. 2013;61:1099–107.PubMedCrossRefGoogle Scholar
  8. 8.
    Feuchtner G, Goetti R, Plass A, et al. Adenosine stress high-pitch 128-slice dual-source myocardial computed tomography perfusion for imaging of reversible myocardial ischemia: comparison with magnetic resonance imaging. Circ Cardiovasc Imaging. 2011;4:540–9.PubMedCrossRefGoogle Scholar

Copyright information

© Japanese Association of Cardiovascular Intervention and Therapeutics 2014

Authors and Affiliations

  • Brian S. Ko
    • 1
  • Marcus Crossett
    • 1
  • Sujith K. Seneviratne
    • 1
  1. 1.Monash Cardiovascular Research Centre, MonashHEART, Department of Medicine, Monash Medical Centre (MMC)Southern Health and Monash UniversityClaytonAustralia

Personalised recommendations