Cardiovascular Intervention and Therapeutics

, Volume 29, Issue 1, pp 11–17

Catheter closure of patent foramen ovale in patients with cryptogenic cerebrovascular accidents: initial experiences in Japan

  • Yasufumi Kijima
  • Teiji Akagi
  • Koji Nakagawa
  • Manabu Taniguchi
  • Akira Ueoka
  • Kentaro Deguchi
  • Norihisa Toh
  • Hiroki Oe
  • Kengo Kusano
  • Shunji Sano
  • Hiroshi Ito
Original Article

DOI: 10.1007/s12928-013-0193-9

Cite this article as:
Kijima, Y., Akagi, T., Nakagawa, K. et al. Cardiovasc Interv and Ther (2014) 29: 11. doi:10.1007/s12928-013-0193-9

Abstract

Although numerous studies have shown an association between a patent foramen ovale (PFO) and cryptogenic cerebrovascular accidents (CVA), there has been no definitive control study that demonstrated the benefit of percutaneous device closure of a PFO compared to medical therapy in patients with CVA. Additionally, few clinical data exist for Japanese patients in this field. We demonstrate the initial experiences in catheter closure of a PFO as secondary prevention of CVA in Japan. Catheter closure of a PFO was attempted in 7 patients who were diagnosed with cryptogenic CVA. Mean age at the procedure was 54 ± 19 years. The presence of spontaneous interatrial right-to-left shunts was demonstrated by transesophageal contrast echocardiography without Valsalva maneuver in all of the patients. Amplatzer Cribriform device (n = 4) or Amplatzer PFO Occluder (n = 3) was used for the procedure and was successfully deployed. Device-related complications were not observed at the time of the procedure or during the follow-up period (mean period of 16 ± 9 months). Catheter closure of a PFO could be safely performed with Amplatzer Cribriform or Amplatzer PFO Occluder. This procedure may contribute to prevention of recurrent cryptogenic CVA in Japanese patients.

Keywords

Patent foramen ovale Catheter intervention Cryptogenic stroke Prevention 

Copyright information

© Japanese Association of Cardiovascular Intervention and Therapeutics 2013

Authors and Affiliations

  • Yasufumi Kijima
    • 1
  • Teiji Akagi
    • 2
  • Koji Nakagawa
    • 1
  • Manabu Taniguchi
    • 3
  • Akira Ueoka
    • 1
  • Kentaro Deguchi
    • 4
  • Norihisa Toh
    • 1
  • Hiroki Oe
    • 1
  • Kengo Kusano
    • 1
  • Shunji Sano
    • 2
  • Hiroshi Ito
    • 1
  1. 1.Department of Cardiovascular MedicineOkayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesOkayamaJapan
  2. 2.Division of Cardiac Intensive Care UnitOkayama University HospitalOkayamaJapan
  3. 3.Department of Cardiovascular MedicineFukuyama Cardiovascular HospitalFukuyamaJapan
  4. 4.Department of NeurologyOkayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesOkayamaJapan

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