Cardiovascular Intervention and Therapeutics

, Volume 28, Issue 1, pp 37–44

Initial results of carotid artery stenting in Japan

  • Yuji Ikari
  • Kazuo Misumi
  • Hiroyoshi Yokoi
  • Nobuhiko Ogata
  • Tomoyuki Umemoto
  • Michitaka Uesugi
  • Yoshihisa Kinoshita
  • Masatsugu Nakano
  • Michiaki Higashitani
  • Hideki Abe
  • Hiroshi Ando
  • Keizou Yamamoto
  • Shuzou Tanimoto
Original Article

DOI: 10.1007/s12928-012-0134-z

Cite this article as:
Ikari, Y., Misumi, K., Yokoi, H. et al. Cardiovasc Interv and Ther (2013) 28: 37. doi:10.1007/s12928-012-0134-z

Abstract

Carotid artery stenting (CAS) was approved by the government and reimbursement was started in 2008 in Japan, probably the last country in the world. CASCARD is a retrospective registry study performed by cardiologists to assess initial results of CAS in Japan. CAS was indicated for patients with at least one high risk factor for carotid endarterectomy and with >50 % stenosis in symptomatic or >80 % stenosis in asymptomatic patients. Primary endpoint was major adverse events (MAE) including death, myocardial infarction and any stroke at 30 days. Between April 2008 and March 2010, a total of 704 cases were enrolled from 55 centers. The study population with an average age of 74 ± 8 years included 62 % asymptomatic patients, with 23 % of cases with contralateral carotid artery occlusion or significant stenoses. Angioguard filter wire was exclusively used as a primary protection device and successfully passed the lesion in 701 cases (99.6 %). Precise stent was implanted successfully in all cases. MAE at 30 days was 3.7:0.3 % death, 0 % myocardial infarction, and 3.4 % stroke (0.4 % major ipsilateral stroke). Death or any stroke rate at 30 days was 2.7 % in asymptomatic and 5.5 % in symptomatic patients. The CASCARD study showed that the initial results of CAS in Japan are acceptable for both symptomatic and asymptomatic cases.

Keywords

Carotid artery Stents Stroke 

Copyright information

© Japanese Association of Cardiovascular Intervention and Therapeutics 2012

Authors and Affiliations

  • Yuji Ikari
    • 1
  • Kazuo Misumi
    • 2
  • Hiroyoshi Yokoi
    • 3
  • Nobuhiko Ogata
    • 1
  • Tomoyuki Umemoto
    • 4
  • Michitaka Uesugi
    • 5
  • Yoshihisa Kinoshita
    • 6
  • Masatsugu Nakano
    • 7
  • Michiaki Higashitani
    • 8
  • Hideki Abe
    • 9
  • Hiroshi Ando
    • 10
  • Keizou Yamamoto
    • 11
  • Shuzou Tanimoto
    • 12
  1. 1.Department of Cardiovascular MedicineTokai University HospitalKanagawaJapan
  2. 2.Chiba-Nishi General HospitalChibaJapan
  3. 3.Kokura Memorial HospitalKokuraJapan
  4. 4.Kasai Cardiology and Neurosurgery HospitalTokyoJapan
  5. 5.Ogaki Municipal HospitalGifuJapan
  6. 6.Toyohashi Heart CenterAichiJapan
  7. 7.Saiseikai Yokohamashi Tobu HospitalKanagawaJapan
  8. 8.Tokyo Women’s Medical University HospitalTokyoJapan
  9. 9.Sanyudo HospitalYamagataJapan
  10. 10.Kasukabe Chuo General HospitalSaitamaJapan
  11. 11.The Sakakibara Heart Institute of OkayamaOkayamaJapan
  12. 12.Mitsui Memorial HospitalTokyoJapan

Personalised recommendations