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Mindfulness

, Volume 10, Issue 2, pp 288–300 | Cite as

Mindfulness-Based Interventions for Psoriasis: a Randomized Controlled Trial

  • Paul D’AltonEmail author
  • Louise Kinsella
  • Orla Walsh
  • Cheryl Sweeney
  • Irene Timoney
  • Maeve Lynch
  • Martin O’Connor
  • Brian Kirby
ORIGINAL PAPER
  • 135 Downloads

Abstract

Psoriasis is a chronic, inflammatory skin disease that has a profound psychological impact. Despite the pertinence of mental health difficulties to psoriasis, the literature is devoid of empirical support for the long-term beneficial effects of mindfulness-based interventions (MBIs). This study aimed to determine the comparative efficacy of mindfulness-based cognitive therapy (MBCT), mindfulness-based self-compassion therapy (MBSCT), and self-help MBSCT (MBSCT-SH) relative to treatment-as-usual (TAU) in improving the long-term psychological and physical outcomes of individuals with psoriasis. Ninety-four adults with mild to moderate psoriasis were randomly assigned to TAU (n = 22) or TAU combined with MBCT (n = 25), MBSCT (n = 25), or MBSCT-SH (n = 22). Participants completed assessments of psychological well-being, psoriasis symptom burden, and quality of life at pre- and post-treatment as well as 6- and 12-month follow-up. Although participants reported that the MBIs were beneficial, no statistically significant differences were found on psychological well-being, psoriasis symptom burden, or quality of life relative to TAU alone at post-treatment, 6- or 12-month follow-up. The development of our understanding of differences in the effects of MBIs for disparate disease groups is instrumental to realizing the therapeutic potential of MBIs.

Keywords

Mindfulness Psoriasis Self-compassion Randomized controlled trial 

Notes

Acknowledgements

The authors would like to thank Drs. Paul Collins and Aoife Lally for their help with the study.

Author Contribution

Paul D’Alton: Study design, intervention delivery, data collection, statistical analysis, and manuscript preparation

Louise Kinsella: Study design, intervention delivery, and data collection

Orla Walsh: Study design and data collection

Cheryl Sweeney: Study design and data collection

Irene Timoney: Study design and data collection

Maeve Lynch: Study design and data collection

Martin O’Connor: Statistical analysis and manuscript preparation

Brian Kirby: Study design, data collection, statistical analysis, and manuscript preparation

Funding

This study was funded by AbbVie Ltd.

Compliance with Ethical Standards

Ethical Approval

Ethical approval for the study was provided by St. Vincent’s Healthcare Group Ethics and Medical Research Committee. All procedures performed were in accordance with the ethical standards of the institutional and/or national research committee and with the Declaration of Helsinki (World Medical Association, 2013) or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Conflict of Interest

The authors declare that they have no conflict of interest.

Supplementary material

12671_2018_973_MOESM1_ESM.docx (33 kb)
ESM 1 (DOCX 33.1 kb)

References

  1. Abbott, R. A., Whear, R., Rodgers, L. R., Bethel, A., Thompson Coon, J., Kuyken, W., … Dickens, C. (2014). Effectiveness of mindfulness-based stress reduction and mindfulness based cognitive therapy in vascular disease: a systematic review and meta-analysis of randomised controlled trials. Journal of Psychosomatic Research, 76(5), 341–351.  https://doi.org/10.1016/j.jpsychores.2014.02.012.
  2. Asadullah, K., Döcke, W. D., Volk, H. D., & Sterry, W. (1999). The pathophysiological role of cytokines in psoriasis. Drugs of Today (Barcelona, Spain), 35(12), 913–924.  https://doi.org/10.1358/dot.1999.35.12.564038.CrossRefGoogle Scholar
  3. Baer, R., Smith, G., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13(1), 27–45.  https://doi.org/10.1177/1073191105283504.CrossRefPubMedGoogle Scholar
  4. Baer, R., Smith, G., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., … Williams, J. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15(3), 329–342.  https://doi.org/10.1177/1073191107313003.
  5. Barnhofer, T., & Crane, C. (2009). Mindfulness-based cognitive therapy for depression and suicidality. In F. Didonna (Ed.), Clinical handbook of mindfulness (pp. 221–244). New York: Springer.CrossRefGoogle Scholar
  6. Basra, M. K., Fenech, R., Gatt, R. M., Salek, M. S., & Finlay, A. Y. (2008). The Dermatology Life Quality Index 1994–2007: a comprehensive review of validation data and clinical results. The British Journal of Dermatology, 159(5), 997–1035.  https://doi.org/10.1111/j.1365-2133.2008.08832.x.CrossRefPubMedGoogle Scholar
  7. Bernhard, J., Kristeller, J., & Kabat-Zinn, J. (1988). Effectiveness of relaxation and visualization techniques as an adjunct to phototherapy and photochemotherapy of psoriasis. Journal of the American Academy of Dermatology, 19(3), 572–573.  https://doi.org/10.1016/S0190-9622(88)80329-3.CrossRefGoogle Scholar
  8. Beugen, S., Middendorp, H., Ferwerda, M., Smit, J. V., Zeeuwen-Franssen, M. E. J., Kroft, E. B. M., … Evers, A. W. M. (2016). Predictors of perceived stigmatization in patients with psoriasis. British Journal of Dermatology.  https://doi.org/10.1111/bjd.14875.
  9. Beygi, S., Lajevardi, V., & Abedini, R. (2014). C-reactive protein in psoriasis: a review of the literature. Journal of the European Academy of Dermatology and Venereology, 28(6), 700–711.  https://doi.org/10.1111/jdv.12257.CrossRefPubMedGoogle Scholar
  10. Bjelland, I., Dahl, A. A., Haug, T. T., & Neckelmann, D. (2002). The validity of the hospital anxiety and depression scale: an updated literature review. Journal of Psychosomatic Research, 52(2), 69–77.  https://doi.org/10.1016/S0022-3999(01)00296-3.CrossRefPubMedGoogle Scholar
  11. Böhm, D., Gissendanner, S., Bangemann, K., Snitjer, I., Werfel, T., Weyergraf, A., … Schmid-Ott, G. (2013). Perceived relationships between severity of psoriasis symptoms, gender, stigmatization and quality of life. Journal of the European Academy of Dermatology and Venereology, 27(2), 220–226.  https://doi.org/10.1111/j.1468-3083.2012.04451.x.
  12. Breines, J., Thoma, M., Gianferante, D., Hanlin, L., Chen, X., & Rohleder, N. (2014). Self-compassion as a predictor of interleukin-6 response to acute psychosocial stress. Brain, Behavior, and Immunity, 37, 109–114.  https://doi.org/10.1016/j.bbi.2013.11.006.CrossRefPubMedGoogle Scholar
  13. Brewer, J., Sinha, R., Chen, J., MA, R., MA, T., Nich, C., … Rounsaville, B. (2009). Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study. Substance Abuse, 30(4), 306–317.  https://doi.org/10.1080/08897070903250241.
  14. Bufka, L. F., & Camp, N. (2010). Brief measures for screening and measuring mental health outcomes. In M. M. Antony & D. H. Barlow (Eds.), Handbook of assessment and treatment planning for psychological disorders (2nd ed., pp. 62–94). New York: The Guilford Press.Google Scholar
  15. Carlson, L., Speca, M., Faris, P., & Patel, K. (2007). One year pre–post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients. Brain, Behavior, and Immunity, 21(8), 1038–1049.  https://doi.org/10.1016/j.bbi.2007.04.002.CrossRefPubMedGoogle Scholar
  16. Cavanagh, K., Strauss, C., Forder, L., & Jones, F. (2014). Can mindfulness and acceptance be learnt by self-help? A systematic review and meta-analysis of mindfulness and acceptance-based self-help interventions. Clinical Psychology Review, 34(2), 118–129.  https://doi.org/10.1016/j.cpr.2014.01.001.CrossRefPubMedGoogle Scholar
  17. Chambers, S., Occhipinti, S., Foley, E., Clutton, S., Legg, M., Berry, M., … Smith, D. (2016). Mindfulness-based cognitive therapy in advanced prostate cancer: a randomized controlled trial. Journal of Clinical Oncology, 35(3), 291–297.  https://doi.org/10.1200/JCO.2016.68.8788.
  18. Chinen, J., & Shearer, W. (2008). Secondary immunodeficiencies, including HIV infection. Journal of Allergy and Clinical Immunology, 121(2), S388–S392.  https://doi.org/10.1016/j.jaci.2007.06.003.CrossRefPubMedGoogle Scholar
  19. Clark, D. M., & Wells, A. A. (1995). A cognitive model of social phobia. In R. G. Heimberg, M. R. Liebowitz, D. A. Hope, & F. R. Schneier (Eds.), Social phobia: diagnosis, assessment, and treatment (pp. 69–93). New York: The Guilford Press.Google Scholar
  20. Cohen, B., Martires, K., & Ho, R. (2016). Psoriasis and the risk of depression in the US population: National Health and Nutrition Examination Survey 2009–2012. JAMA Dermatology, 152(1), 73–79.  https://doi.org/10.1001/jamadermatol.2015.3605.CrossRefPubMedGoogle Scholar
  21. Corcoran, K. J., & Fischer, J. (2013). Measures for clinical practice and research: a sourcebook (5th ed.). New York: Oxford University Press.Google Scholar
  22. Coronado-Montoya, S., Levis, A., Kwakkenbos, L., Steele, R., Turner, E., & Thombs, B. (2016). Reporting of positive results in randomized controlled trials of mindfulness-based mental health interventions. PLoS One, 11(4), e0153220.  https://doi.org/10.1371/journal.pone.0153220.CrossRefPubMedPubMedCentralGoogle Scholar
  23. Crane, C., Crane, R., Eames, C., Fennell, M., Silverton, S., Williams, J., & Barnhofer, T. (2014). The effects of amount of home meditation practice in mindfulness based cognitive therapy on hazard of relapse to depression in the staying well after depression trial. Behaviour Research and Therapy, 63, 17–24.  https://doi.org/10.1016/j.brat.2014.08.015.CrossRefPubMedPubMedCentralGoogle Scholar
  24. Eisendrath, S. J., Gillung, E., Hartzler, A., James-Myers, M., Wolkowitz, O., Sipe, W., … Delucchi, K. (2016). Mindfulness-based cognitive therapy associated with decreases in C-reactive protein in major depressive disorder: a pilot study. alternative, Complementary & Integrative Medicine, 2(1), 1–3.  https://doi.org/10.24966/ACIM-7562/100010.
  25. Farias, M., & Wikholm, C. (2016). Has the science of mindfulness lost its mind? BJPsych Bulletin, 40(6), 329–332.  https://doi.org/10.1192/pb.bp.116.053686.CrossRefPubMedPubMedCentralGoogle Scholar
  26. Farshchian, M., Ansar, A., Sobhan, M., & Hoseinpoor, V. (2016). C-reactive protein serum level in patients with psoriasis before and after treatment with narrow-band ultraviolet B. Anais Brasileiros de Dermatologia, 91(5), 580–583.  https://doi.org/10.1590/abd1806-4841.20164655.CrossRefPubMedPubMedCentralGoogle Scholar
  27. Faul, F., Erdfelder, E., Buchner, A., & Lang, A. G. (2009). Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses. Behavior Research Methods, 41(4), 1149–1160.  https://doi.org/10.3758/BRM.41.4.1149.CrossRefPubMedGoogle Scholar
  28. Ferreira, B. I. I., Abreu, J. L. L., Reis, J. P. P., & Figueiredo, A. M. M. (2016). Psoriasis and associated psychiatric disorders: a systematic review on etiopathogenesis and clinical correlation. The Journal of Clinical and Aesthetic Dermatology, 9(6), 36–43.PubMedPubMedCentralGoogle Scholar
  29. Finlay, A. Y., & Khan, G. K. (1994). Dermatology Life Quality Index (DLQI)—a simple practical measure for routine clinical use. Clinical and Experimental Dermatology, 19(3), 210–216.CrossRefGoogle Scholar
  30. Fleming, P., Bai, J. W., Pratt, M., Sibbald, C., Lynde, C., & Gulliver, W. P. (2016). The prevalence of anxiety in patients with psoriasis: a systematic review of observational studies and clinical trials. Journal of the European Academy of Dermatology and Venereology.  https://doi.org/10.1111/jdv.13891.
  31. Fordham, B., Griffiths, C. E. M., & Bundy, C. (2015). A pilot study examining mindfulness-based cognitive therapy in psoriasis. Psychology, Health & Medicine, 20(1), 121–127.  https://doi.org/10.1080/13548506.2014.902483.CrossRefGoogle Scholar
  32. Fortune, D. G. G., Richards, H. L., Corrin, A., Taylor, R. J., Griffiths, C. E., & Main, C. J. (2003a). Attentional bias for psoriasis-specific and psychosocial threat in patients with psoriasis. Journal of Behavioral Medicine, 26(3), 211–224.CrossRefGoogle Scholar
  33. Fortune, D. G., Richards, H. L., Kirby, B., McElhone, K., Markham, T., Rogers, S., … Griffiths, C. E. (2003b). Psychological distress impairs clearance of psoriasis in patients treated with photochemotherapy. Archives of Dermatology, 139(6), 752–6.  https://doi.org/10.1001/archderm.139.6.752.
  34. Fredriksson, T., & Pettersson, U. (1978). Severe psoriasis—oral therapy with a new retinoid. Dermatologica, 157, 238–244.  https://doi.org/10.1159/000250839.CrossRefPubMedGoogle Scholar
  35. Gilbert, P. (2010). Compassion focused therapy: distinctive features. New York: Routledge.Google Scholar
  36. Gilbert, P., & Choden, P. (2013). Mindful compassion: using the power of mindfulness and compassion to transform our lives (1st ed.). London: Robinson.Google Scholar
  37. Gilbert, P., McEwan, K., Matos, M., & Rivis, A. (2011). Fears of compassion: development of three self-report measures. Psychology and Psychotherapy: Theory, Research and Practice, 84(3), 239–255.  https://doi.org/10.1348/147608310X526511.CrossRefGoogle Scholar
  38. Graham, M. R., Baker, J. S., Evans, P., & Davies, B. (2009). Physiological effects and disease manifestations of performance-enhancing androgenic-anabolic steroids, growth hormone and insulin. In K. Maiese (Ed.), Neurovascular medicine: pursuing cellular longevity for healthy aging (pp. 174–214). New York: Oxford University Press.CrossRefGoogle Scholar
  39. Guardino, C., Schetter, C., Bower, J., Lu, M., & Smalley, S. (2014). Randomised controlled pilot trial of mindfulness training for stress reduction during pregnancy. Psychology & Health, 29(3), 334–349.  https://doi.org/10.1080/08870446.2013.852670.CrossRefGoogle Scholar
  40. Harinck, F., Nagtegaal, T., Kluijt, I., Aalfs, C., Smets, E., Poley, J., … Bleiker, E. M. (2011). Feasibility of a pancreatic cancer surveillance program from a psychological point of view. Genetics in Medicine, 13(12), 1015–1024.  https://doi.org/10.1097/gim.0b013e31822934f5.
  41. Hayes, S. C., Wilson, K. G., Gifford, E. V., Follette, V. M., & Strosahl, K. (1996). Experiential avoidance and behavioral disorders: a functional dimensional approach to diagnosis and treatment. Journal of Consulting and Clinical Psychology, 64(6), 1152–1168.  https://doi.org/10.1037//0022-006x.64.6.1152.CrossRefPubMedGoogle Scholar
  42. Hayes, S. C., Strosahl, K. D., & Wilson, K. G. (2012). Acceptance and commitment therapy: the process and practice of mindful change (2nd ed.). New York: The Guilford Press.Google Scholar
  43. Herrmann, C. (1997). International experiences with the hospital anxiety and depression scale—a review of validation data and clinical results. Journal of Psychosomatic Research, 42(1), 17–41.  https://doi.org/10.1016/S0022-3999(96)00216-4.CrossRefPubMedGoogle Scholar
  44. Higgins, J. P., Altman, D. G., & Sterne, J. A. (2011). Assessing risk of bias in included studies. In J. P. Higgins & S. Green (Eds.), Cochrane handbook for systematic reviews of interventions version 5.1.0. Retrieved from www.cochrane-handbook.org
  45. Hofmann, S., Sawyer, A., Witt, A., & Oh, D. (2010). The effect of mindfulness-based therapy on anxiety and depression: a meta-analytic review. Journal of Consulting and Clinical Psychology, 78(2), 169.  https://doi.org/10.1037/a0018555.CrossRefPubMedPubMedCentralGoogle Scholar
  46. Hoge, E., Bui, E., Palitz, S., Schwarz, N., Owens, M., Johnston, J., … Simon, N. (2018). The effect of mindfulness meditation training on biological acute stress responses in generalized anxiety disorder. Psychiatry Research, 262.  https://doi.org/10.1016/j.psychres.2017.01.006.
  47. Kabat-Zinn, J. (2012). Mindfulness for beginners. Boulder: Sounds True, Inc.Google Scholar
  48. Kabat-Zinn, J., Wheeler, E., Light, T., Skillings, A., Scharf, M. J., Cropley, T. G., … Bernhard, J. D. (1998). Influence of a mindfulness meditation-based stress reduction intervention on rates of skin clearing in patients with moderate to severe psoriasis undergoing phototherapy (UVB) and photochemotherapy (PUVA). Psychosomatic Medicine, 60(5), 625–32.Google Scholar
  49. Kelly, A., Zuroff, D., & Shapira, L. (2009). Soothing oneself and resisting self-attacks: the treatment of two intrapersonal deficits in depression vulnerability. Cognitive Therapy and Research, 33(3), 301–313.  https://doi.org/10.1007/s10608-008-9202-1.CrossRefGoogle Scholar
  50. Kelly-Sell, M., & Gudjonsson, J. E. (2017). Overview of psoriasis. In J. Wu, S. Feldman, & M. Lebwohl (Eds.), Therapy for severe psoriasis (pp. 1–16). Philadelphia: Elsevier.Google Scholar
  51. Kimball, A. B., Jacobson, C., Weiss, S., Vreeland, M. G., & Wu, Y. (2005). The psychosocial burden of psoriasis. American Journal of Clinical Dermatology, 6(6), 383–392.CrossRefGoogle Scholar
  52. Köhler, C., Freitas, T., Maes, M., Andrade, N., Liu, C., Fernandes, B., … Carvalho, A. (2017). Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies. Acta Psychiatrica Scandinavica, 135(5), 373–387.  https://doi.org/10.1111/acps.12698.
  53. Kong, X. M., Zhu, W. Q., Hong, J. X., & Sun, X. H. (2014). Is glaucoma comprehension associated with psychological disturbance and vision-related quality of life for patients with glaucoma? A cross-sectional study. BMJ Open, 4, e004632.  https://doi.org/10.1136/bmjopen-2013-004632.CrossRefPubMedPubMedCentralGoogle Scholar
  54. Kouris, A., Pistiki, A., Katoulis, A., Georgitsi, M., Giatrakou, S., Papadavid, E., … Giamarellos-Bourboulis, E. (2014). Proinflammatory cytokine responses in patients with psoriasis. European Cytokine Network.  https://doi.org/10.1684/ecn.2014.0358.
  55. Kuijpers, H. J., Van der Heijden, F. M., Tuinier, S., & Verhoeven, W. M. (2007). Meditation-induced psychosis. Psychopathology, 40(6), 461–464.  https://doi.org/10.1159/000108125.CrossRefPubMedGoogle Scholar
  56. Kuyken, W., Watkins, E., Holden, E., White, K., Taylor, R., Byford, S., … Dalgleish, T. (2010). How does mindfulness-based cognitive therapy work? Behaviour Research and Therapy,48(11), 1105–1112.  https://doi.org/10.1016/j.brat.2010.08.003.
  57. Lavda, A. C., Webb, T. L., & Thompson, A. R. (2012). A meta-analysis of the effectiveness of psychological interventions for adults with skin conditions. British Journal of Dermatology, 167(5), 970–979.  https://doi.org/10.1111/j.1365-2133.2012.11183.x.CrossRefPubMedGoogle Scholar
  58. Ledesma, D., & Kumano, H. (2009). Mindfulness-based stress reduction and cancer: a meta-analysis. Psycho-Oncology, 18(6), 571–579.  https://doi.org/10.1002/pon.1400.CrossRefPubMedGoogle Scholar
  59. Magin, P., Adams, J., Heading, G., Pond, D., & Smith, W. (2009). The psychological sequelae of psoriasis: results of a qualitative study. Psychology, Health & Medicine, 14(2), 150–161.  https://doi.org/10.1080/13548500802512294.CrossRefGoogle Scholar
  60. Malinowski, P., Moore, A. W., Mead, B. R., & Gruber, T. (2017). Mindful aging: the effects of regular brief mindfulness practice on electrophysiological markers of cognitive and affective processing in older adults. Mindfulness, 8(1), 78–94.  https://doi.org/10.1007/s12671-015-0482-8.CrossRefPubMedGoogle Scholar
  61. McBride, J. D., & Cooper, M. A. (2008). A high sensitivity assay for the inflammatory marker C-reactive protein employing acoustic biosensing. Journal of Nanobiotechnology, 6(1), 5.  https://doi.org/10.1186/1477-3155-6-5.CrossRefPubMedPubMedCentralGoogle Scholar
  62. McCusker, C., & Warrington, R. (2011). Primary immunodeficiency. Allergy, Asthma & Clinical Immunology, 7, S1), 1–S1), 8.  https://doi.org/10.1186/1710-1492-7-S1-S11.CrossRefGoogle Scholar
  63. Meyer, T. J., Miller, M. L., Metzger, R. L., & Borkovec, T. (1990). Development and validation of the Penn State Worry Questionnaire. Behaviour Research and Therapy, 28(6), 487–495.  https://doi.org/10.1016/0005-7967(90)90135-6.CrossRefPubMedGoogle Scholar
  64. Montgomery, K., Norman, P., Messenger, A. G., & Thompson, A. R. (2016). The importance of mindfulness in psychosocial distress and quality of life in dermatology patients. British Journal of Dermatology, 175(5), 930–936.  https://doi.org/10.1111/bjd.14719.CrossRefPubMedGoogle Scholar
  65. Moon, H.-S., Mizara, A., & McBride, S. (2013). Psoriasis and psycho-dermatology. Dermatology and Therapy, 3(2), 117–130.  https://doi.org/10.1007/s13555-013-0031-0.CrossRefPubMedPubMedCentralGoogle Scholar
  66. Murphy, R., Cooper, Z., Hollon, S. D., & Fairburn, C. G. (2009). How do psychological treatments work? Investigating mediators of change. Behaviour Research and Therapy, 47(1), 1–5.  https://doi.org/10.1016/j.brat.2008.10.001.CrossRefPubMedPubMedCentralGoogle Scholar
  67. Neff, K. (2016). The self-compassion scale is a valid and theoretically coherent measure of self-compassion. Mindfulness, 7(1), 264–274.  https://doi.org/10.1007/s12671-015-0479-3.CrossRefGoogle Scholar
  68. Neff, K. D., & Germer, C. K. (2012). A pilot study and randomized controlled trial of the mindful self-compassion program. Journal of Clinical Psychology, 69(1), 28–44.  https://doi.org/10.1002/jclp.21923.CrossRefPubMedGoogle Scholar
  69. Nicholl, C. R., Lincoln, N. B., Francis, V. M., & Stephan, T. F. (2001). Assessment of emotional problems in people with multiple sclerosis. Clinical Rehabilitation, 15(6), 657–668.  https://doi.org/10.1191/0269215501cr427oa.CrossRefPubMedGoogle Scholar
  70. Nordlind, K., & Zalewska-Janowska, A. (2016). Skin and psyche. Sharjah: Bentham Science Publishers.CrossRefGoogle Scholar
  71. Parsons, C. E., Crane, C., Parsons, L. J., Fjorback, L. O., & Kuyken, W. (2017). Home practice in mindfulness-based cognitive therapy and mindfulness-based stress reduction: a systematic review and meta-analysis of participants' mindfulness practice and its association with outcomes. Behaviour Research and Therapy, 95, 29–41.  https://doi.org/10.1016/j.brat.2017.05.004.CrossRefPubMedPubMedCentralGoogle Scholar
  72. Pietrzak, D., Pietrzak, A., Krasowska, D., Makara-Studzińska, M., Madej, A., Baranowska, M., & Borzęcki, A. (2017). Depressiveness, measured with Beck Depression Inventory, in patients with psoriasis. Journal of Affective Disorders, 209, 229–234.  https://doi.org/10.1016/j.jad.2016.11.045.CrossRefPubMedGoogle Scholar
  73. Rapee, R. M., & Heimberg, R. G. (1997). A cognitive-behavioral model of anxiety in social phobia. Behaviour Research and Therapy, 35(8), 741–756.  https://doi.org/10.1016/s0005-7967(97)00022-3.CrossRefPubMedGoogle Scholar
  74. Rockliff, H., Karl, A., McEwan, K., Gilbert, J., Matos, M., & Gilbert, P. (2011). Effects of intranasal oxytocin on ‘compassion focused imagery’. Emotion, 11(6), 1388–1396.  https://doi.org/10.1037/a0023861.CrossRefPubMedGoogle Scholar
  75. Rodríguez-Carvajal, R., García-Rubio, C., Paniagua, D., García-Diex, G., & Rivas, S. (2016). Mindfulness Integrative Model (MIM): Cultivating positive states of mind towards oneself and the others through mindfulness and self-compassion. Anales de Psicología, 32(3), 749–760.  https://doi.org/10.6018/analesps.32.3.261681.CrossRefGoogle Scholar
  76. Schulz, K. F., Altman, D. G., & Moher, D. (2010). CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. BMC Medicine, 8(1), 18.  https://doi.org/10.1186/1741-7015-8-18.CrossRefPubMedPubMedCentralGoogle Scholar
  77. Segal, Z. V., Williams, J. M., & Teasdale, J. D. (2002). Mindfulness-based cognitive therapy for depression: a new approach to preventing relapse. New York: Guilford Press.Google Scholar
  78. Shapiro, D. H. (1992). Adverse effects of meditation: a preliminary investigation of long-term meditators. International Journal of Psychosomatics, 39, 62–67.PubMedGoogle Scholar
  79. Skevington, S. M., Lofty, M., & O'Connell, K. A. (2004). The World Health Organization’s WHOQOL-BREF quality of life assessment: psychometric properties and results of the international field trial. Quality of Life Research, 13(2), 299–310.  https://doi.org/10.1023/B:QURE.0000018486.91360.00.CrossRefPubMedGoogle Scholar
  80. Snaith, R. (2003). The hospital anxiety and depression scale. Health and Quality of Life Outcomes, 1(1), 1–4.  https://doi.org/10.1186/1477-7525-1-29.CrossRefGoogle Scholar
  81. Szabo, T. G., Long, D. M., Villatte, M., & Hayes, S. C. (2015). Mindfulness in contextual cognitive-behavioral models. In K. W. Brown, J. D. Creswell, & R. M. Ryan (Eds.), Handbook of mindfulness: theory, research, and practice (pp. 130–147). New York: The Guilford Press.Google Scholar
  82. Takeshita, J., Grewal, S., Langan, S., Mehta, N., Ogdie, A., Voorhees, A., & Gelfand, J. (2017). Psoriasis and comorbid diseases epidemiology. Journal of the American Academy of Dermatology, 76(3), 377–390.  https://doi.org/10.1016/j.jaad.2016.07.064.CrossRefPubMedPubMedCentralGoogle Scholar
  83. Teasdale, J., Segal, Z., Williams, J., Ridgeway, V., Soulsby, J., & Lau, M. (2000). Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Consulting and Clinical Psychology, 68(4), 615–623.  https://doi.org/10.1037//0022-006X.68.4.615.CrossRefPubMedGoogle Scholar
  84. Vogelzangs, N., Beekman, A., Jonge, P., & Penninx, B. (2013). Anxiety disorders and inflammation in a large adult cohort. Translational Psychiatry, 3(4), tp201327.  https://doi.org/10.1038/tp.2013.27.CrossRefGoogle Scholar
  85. Whitebird, R. R., Kreitzer, M. J., Vazquez-Benitez, G., & Enstad, C. J. (2017). Reducing diabetes distress and improving self-management with mindfulness. Social Work in Health Care, 57(1), 48–65.  https://doi.org/10.1080/00981389.2017.1388898.CrossRefPubMedGoogle Scholar
  86. WHOQOL Group. (1998). Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychological Medicine, 28(3), 551–558.  https://doi.org/10.1017/S0033291798006667.CrossRefGoogle Scholar
  87. Woolhouse, H., Mercuri, K., Judd, F., & Brown, S. (2014). Antenatal mindfulness intervention to reduce depression, anxiety and stress: a pilot randomised controlled trial of the MindBabyBody program in an Australian tertiary maternity hospital. BMC Pregnancy and Childbirth, 14(1).  https://doi.org/10.1186/s12884-014-0369-z.
  88. World Medical Association. (2013). Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA, 310(20), 2191–2194.  https://doi.org/10.1001/jama.2013.281053.CrossRefGoogle Scholar
  89. Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica, 67, 361–370.  https://doi.org/10.1111/j.1600-0447.1983.tb09716.x.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Paul D’Alton
    • 1
    Email author
  • Louise Kinsella
    • 1
  • Orla Walsh
    • 1
  • Cheryl Sweeney
    • 1
  • Irene Timoney
    • 1
  • Maeve Lynch
    • 1
  • Martin O’Connor
    • 1
  • Brian Kirby
    • 1
  1. 1.St. Vincent’s University HospitalDublin 4Ireland

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