Mindfulness-Based Interventions for Psoriasis: a Randomized Controlled Trial
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Psoriasis is a chronic, inflammatory skin disease that has a profound psychological impact. Despite the pertinence of mental health difficulties to psoriasis, the literature is devoid of empirical support for the long-term beneficial effects of mindfulness-based interventions (MBIs). This study aimed to determine the comparative efficacy of mindfulness-based cognitive therapy (MBCT), mindfulness-based self-compassion therapy (MBSCT), and self-help MBSCT (MBSCT-SH) relative to treatment-as-usual (TAU) in improving the long-term psychological and physical outcomes of individuals with psoriasis. Ninety-four adults with mild to moderate psoriasis were randomly assigned to TAU (n = 22) or TAU combined with MBCT (n = 25), MBSCT (n = 25), or MBSCT-SH (n = 22). Participants completed assessments of psychological well-being, psoriasis symptom burden, and quality of life at pre- and post-treatment as well as 6- and 12-month follow-up. Although participants reported that the MBIs were beneficial, no statistically significant differences were found on psychological well-being, psoriasis symptom burden, or quality of life relative to TAU alone at post-treatment, 6- or 12-month follow-up. The development of our understanding of differences in the effects of MBIs for disparate disease groups is instrumental to realizing the therapeutic potential of MBIs.
KeywordsMindfulness Psoriasis Self-compassion Randomized controlled trial
The authors would like to thank Drs. Paul Collins and Aoife Lally for their help with the study.
Paul D’Alton: Study design, intervention delivery, data collection, statistical analysis, and manuscript preparation
Louise Kinsella: Study design, intervention delivery, and data collection
Orla Walsh: Study design and data collection
Cheryl Sweeney: Study design and data collection
Irene Timoney: Study design and data collection
Maeve Lynch: Study design and data collection
Martin O’Connor: Statistical analysis and manuscript preparation
Brian Kirby: Study design, data collection, statistical analysis, and manuscript preparation
This study was funded by AbbVie Ltd.
Compliance with Ethical Standards
Ethical approval for the study was provided by St. Vincent’s Healthcare Group Ethics and Medical Research Committee. All procedures performed were in accordance with the ethical standards of the institutional and/or national research committee and with the Declaration of Helsinki (World Medical Association, 2013) or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
Conflict of Interest
The authors declare that they have no conflict of interest.
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