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The effectiveness of mindfulness meditation in relief of symptoms of depression and quality of life in patients with gastroesophageal reflux disease

  • Suhas ChandranEmail author
  • Rajesh Raman
  • M. Kishor
  • H. P. Nandeesh
Original Article
  • 14 Downloads

Abstract

Background

The role of psychological comorbidities in patients with gastroesophageal reflux disease (GERD), a common condition, still remains incompletely understood. Depression may intensify the symptoms and lower quality of life in these patients. In this study, we looked at the effectiveness of mindfulness-based stress reduction (MBSR) in relieving the symptoms of depression and the health-related quality of life of these patients.

Methods

A longitudinal, interventional open-label study was carried out on 60 patients with GERD and 60 controls. Zung Self-Rating Depression Scale (ZSDS) was used for assessing depression before and after the intervention. The GERD-Health-Related Quality of Life (GERD-HRQL) questionnaire was used to assess the health-related quality of life and the Freiburg Mindfulness Inventory (FMI) to quantify the amount of mindfulness over the study period. The correlation between the above variables was analyzed.

Result

Compared with the group not receiving MBSR, the group receiving MBSR showed a greater decrease in the levels of depression indicated by changes in the ZSDS (p < 0.001). According to the GERD-HRQL questionnaire, mental health and social functioning significantly correlated with symptoms of depression and reduction in the levels of distress and in the improvement in health-related quality of life were greater in the group receiving MBSR (p < 0.001).

Conclusion

Depressive symptoms adversely influence GERD, reducing the overall quality of life. MBSR can be an effective modality in the alleviation of these symptoms and in reduction in the levels of distress in GERD patients.

Keywords

Depression Gastroesophageal reflux disease Mindfulness-based stress reduction Quality of life 

Notes

Compliance with ethical standards

Conflict of interest

SC, RR, MK, and HPN declare that they have no conflict of interest.

Ethical clearance

The authors declare that the study was performed in a manner conforming to the Helsinki declaration of 1975, as revised in 2000 and 2008 concerning human and animal rights, and the authors followed the policy concerning informed consent as shown on Springer.com. Permission was obtained from the JSS Medical College and Hospital Ethics Committee.

Disclaimer

The authors are solely responsible for the data and the content of the paper. In no way, the Honorary Editor-in-Chief, Editorial Board Members, or the printer/publishers are responsible for the results/findings and content of this article.

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Copyright information

© Indian Society of Gastroenterology 2019

Authors and Affiliations

  • Suhas Chandran
    • 1
    Email author
  • Rajesh Raman
    • 1
  • M. Kishor
    • 1
  • H. P. Nandeesh
    • 2
  1. 1.Department of PsychiatryJSS Medical College and Hospital, JSS Academy of Higher Education and ResearchBannimantapIndia
  2. 2. Department of GastroenterologyJSS Medical College and Hospital, JSS Academy of Higher Education and ResearchBannimantapIndia

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