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Indian Journal of Gastroenterology

, Volume 38, Issue 1, pp 55–60 | Cite as

Legume intake and risk of nonalcoholic fatty liver disease

  • Alireza Bahrami
  • Farshad Teymoori
  • Tannaz Eslamparast
  • Golbon Sohrab
  • Ehsan Hejazi
  • Hossein Poustchi
  • Azita HekmatdoostEmail author
Original Article
  • 52 Downloads

Abstract

Background

It is known that diet plays a pivotal role in the pathogenesis and management of nonalcoholic fatty liver disease (NAFLD); however, the knowledge on the role of different food groups such as legumes is not enough.

Methods

We designed this study to assess the relationship between legume intake and risk of NAFLD in framework of a case-control study among Tehrani adults. One hundred and ninety-six newly diagnosed patients with NAFLD and 803 controls were studied, and their dietary intake was assessed using a valid and reliable food frequency questionnaire. Conditional logistic regression was used to determine the odds ratio (OR) of NAFLD per increase of one serving/week dietary legumes, lentil, and beans adjusting for potential confounders.

Results

In energy-adjusted model, greater intake of legumes, lentils, and beans was associated with a lower risk of NAFLD. These risk associations remained significant after adjusting for all known risk factors of NAFLD. OR of NAFLD in adjusted models for higher dietary intake of legumes, lentils, and beans were 0.73 (0.64–0.84), 0.61 (0.46–0.78), and 0.35 (0.17–0.74), respectively.

Conclusion

Our findings suggest that higher intake of total legumes (beans, lentils, and peas) was associated with lower risk of NAFLD.

Keywords

Bean Legumes Lentil Nonalcoholic fatty liver disease 

Notes

Acknowledgments

This study is related to the project NO. 1396/114499 From Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding information

The “Student Research Committee” and “Research and Technology Chancellor” in Shahid Beheshti University of Medical Sciences financially supported this study.

Compliance with ethical standards

Conflict of interest

AB, FT, TE, GS, EH, HP, and AH declare that they have no conflict of interest.

Ethics statement

The authors declare that the study was performed in a manner conforming to the Helsinki declaration of 1975, as revised in 2000 and 2008 concerning human and animal rights, and the authors followed the policy concerning informed consent as shown on Springer. com. The study was approved by the ethics committee of National Nutrition and Food Technology Research Institute, Tehran, Iran.

Disclaimer

The authors are solely responsible for the data and the content of the paper. In no way, the Honorary Editor-in-Chief, Editorial Board Members, or the printer/publishers are responsible for the results/findings and content of this article.

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Copyright information

© Indian Society of Gastroenterology 2019

Authors and Affiliations

  • Alireza Bahrami
    • 1
  • Farshad Teymoori
    • 1
  • Tannaz Eslamparast
    • 2
  • Golbon Sohrab
    • 2
  • Ehsan Hejazi
    • 2
  • Hossein Poustchi
    • 3
  • Azita Hekmatdoost
    • 2
    Email author
  1. 1.Student Research Committee, Department and Faculty of Nutrition Sciences and Food TechnologyShahid Beheshti University of Medical SciencesTehranIran
  2. 2.Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research InstituteShahid Beheshti University of Medical SciencesTehranIran
  3. 3.Liver and Pancreatobiliary Research GroupDigestive Disease Research InstituteTehranIran

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