Indian Journal of Gastroenterology

, Volume 36, Issue 3, pp 209–216 | Cite as

Budd-Chiari syndrome: outcomes of endovascular intervention—A single-center experience

  • Nitin JagtapEmail author
  • Mithun Sharma
  • Jagdeesh Singh
  • Manu Tandan
  • P N Rao
  • Rajesh Gupta
  • Sundeep Lakhtakia
  • Mohan Ramchandani
  • Harshal Shah
  • T Mahesh Kumar
  • Santosh Darishetty
  • G V Rao
  • D N Reddy
Original Article



Outcomes of endovascular intervention in Budd-Chiari syndrome (BCS) have been reported with varied results. Clinical outcomes of endovascular interventions in BCS and role of various prognostic scores were critically evaluated in this study.


This study retrospectively analyzed consecutive patients of BCS who underwent endovascular intervention between January 2007 and May 2016 at our center. Technical, clinical successes and complications were documented. The role of the prognostic scores such as Child-Turcotte-Pugh (CTP), model for end-stage liver disease (MELD), Rotterdam index, and original Clichy score in predicting mortality, clinical success, and need for re-interventions were also assessed.


A total of 88 patients were analyzed. The median follow up was 12 months (range 1–96 months). Thirteen (14.8%) patients had combined inferior vena cava (IVC) and hepatic vein (HV) obstruction; HV obstruction in 33 (37.5%) and inferior vena cava IVC obstruction in 42 (47.7%) patients. The following interventions were done: IVC angioplasty alone (n = 11), IVC angioplasty with stenting (n = 36), HV angioplasty with stenting (n = 26), combined HV and IVC stent (n = 2), and direct intrahepatic porto-systemic shunt (DIPS) (n = 13). Overall technical success was 87/88 (98.86%), and clinical success was 76/88 (86.36%). Immediate complications were noted in 8 patients (10%). The 1-, 2-, 3-, and 4-year stent patency rates were 90.91%, 81.08%, 74.59%, and 70.45%, respectively. Re-interventions were required in 15 (17%). Overall mortality was 6 (6.8%). Apart from MELD >14, none of the other prognostic score could predict mortality, clinical success, and need for re-interventions.


Endovascular interventions play an important role in the management of BCS, in properly selected patients, even if prognostic score is unfavorable.


Budd-Chiari syndrome DIPS Endovascular interventions Prognostic scores 


Compliance with ethical standards

Conflict of interest

NJ, MS, JS, MT, PNR, RG, SL, MR, HS, TMK, SD, GVR, and DNR declare that they have no conflict of interest.

Human and animal rights

All procedures performed in patients were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments.

Supplementary material

12664_2017_760_MOESM1_ESM.docx (15 kb)
ESM 1 (DOCX 14 kb)


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Copyright information

© Indian Society of Gastroenterology 2017

Authors and Affiliations

  • Nitin Jagtap
    • 1
    Email author
  • Mithun Sharma
    • 1
  • Jagdeesh Singh
    • 1
  • Manu Tandan
    • 1
  • P N Rao
    • 1
  • Rajesh Gupta
    • 1
  • Sundeep Lakhtakia
    • 1
  • Mohan Ramchandani
    • 1
  • Harshal Shah
    • 1
  • T Mahesh Kumar
    • 1
  • Santosh Darishetty
    • 1
  • G V Rao
    • 1
  • D N Reddy
    • 1
  1. 1.Department of Gastroenterology and HepatologyAsian Institute of GastroenterologyHyderabadIndia

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