Journal of Maxillofacial and Oral Surgery

, Volume 14, Issue 3, pp 728–734 | Cite as

Management and Treatment Outcomes of Maxillofacial Fibro-osseous Lesions: A Retrospective Study

  • K. A. Jeevan Kumar
  • P. Krishna Kishore
  • A. P. Mohan
  • V. Venkatesh
  • B. Pavan Kumar
  • Divya Gandla
Clinical Paper

Abstract

Introduction

Fibro-osseous lesions are a diverse group of bone disorders and include developmental, reactive or dysplastic diseases and neoplasms. They share overlapping clinical, radiographic and histopathologic features and demonstrate a wide range of biological behaviour.

Aim

To evaluate the characteristics, treatment and outcome of benign fibro-osseous lesions of the jaws.

Patients and Method

All patients with fibro-osseous lesions of the jaws treated at the department of Oral and Maxillofacial Surgery of the Kamineni Institute of Dental Sciences from 2007 to 2013 were included in this study.

Results

Six males and four females were treated. Juvenile ossifying fibroma was most often encountered (40 %), and the mandible was the most frequent location (70 %). Main clinical feature in most of the cases was a painless expansile swelling with facial asymmetry, and radiologically mixed (radiolucent and radiopaque lesions) were seen in majority of cases. All cases were surgically treated and histopathologically confirmed. Segmental ostectomy was performed in six cases; maxillectomy was done in one case and excision along with margin in three cases. Mean follow-up was of 3.3 years with no recurrence.

Conclusions

Fibro-osseous lesions, although sharing similar microscopic features, exhibit a variety of clinical behavior rendering their treatment highly individualized. Radical treatment is the choice to achieve an outcome without recurrence.

Keywords

Maxillofacial Juvenile ossifying fibroma Children Ossifying fibroma 

References

  1. 1.
    Mehta D, Clifton N, McClelland L, Jones NS (2006) Paediatric fibro-osseous lesions of the nose and paranasal sinuses. Int J Pediatr Otorhinolaryngol 70:193–199PubMedCrossRefGoogle Scholar
  2. 2.
    Waldron CA (1985) Fibro-osseous lesions of the jaws. J Oral Maxillofac Surg 43:249–262PubMedCrossRefGoogle Scholar
  3. 3.
    Waldron CA (1993) Fibro-osseous lesions of the jaws. J Oral Maxillofac Surg 51:828–835PubMedCrossRefGoogle Scholar
  4. 4.
    Kramer IRH, Pindborg JJ, Shear M (1992) Histological typing of odontogenic tumours WHO international classification of tumours, 2nd edn. Springer, LondonCrossRefGoogle Scholar
  5. 5.
    Kramer I, Pindborg J, Shear M (1993) The WHO histological typing of odontogenic tumors, a commentary on the second edition. Cancer 70:2988–2994CrossRefGoogle Scholar
  6. 6.
    Vegas Bustamante E, Gargallo Albiol J, Berini Aytés L, Gay Escoda C (2008) Benign fibro-osseous lesions of the maxillas: analysis of 11 cases. Med Oral Pathol Oral Cir Bucal 13:653–656Google Scholar
  7. 7.
    Slootweg PJ, Panders AK, Koopmans R, Nikkels PGJ (1994) Juvenile ossifying fibroma. An analysis of 33 cases with emphasis on histopathological aspects. J Oral Pathol Med 23:385–388PubMedCrossRefGoogle Scholar
  8. 8.
    Abdelsayed RA, Eversole LR, Singh BS, Scarbrough FE (2001) Gigantiform cementoma: clinicopathologic presentation of 3 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91:438–444PubMedCrossRefGoogle Scholar
  9. 9.
    Sarwar HG, Jindal MK, Ahmad SS (2008) Cemento-ossifying fibroma—a rare case. J Indian Soc Pedod Prev Dent 26:128–131PubMedCrossRefGoogle Scholar
  10. 10.
    Hamner JE III, Scofield HH, Cornyn J (1968) Benign fibro-osseous jaw lesions of periodontal membrane origin. An analysis of 249 cases. Cancer 22:861–878PubMedCrossRefGoogle Scholar
  11. 11.
    Khanna S, Khanna NN, Varanasi MS (1979) Primary tumors of the jaws in children. J Oral Surg 37:800–804PubMedGoogle Scholar
  12. 12.
    Panda NK, Parida PK, Sharma R, Jain A, Bapuraj JR (2007) A clinicoradiologic analysis of symptomatic craniofacial fibro-osseous lesions. Otolaryngol Head Neck Surg 136:928–933PubMedCrossRefGoogle Scholar
  13. 13.
    Lustig LR, Holliday MJ, McCarthy F, Nager GT (2001) Fibrous dysplasia involving the skull base and temporal bone. Arch Otolaryngol Head Neck Surg 127:1239–1247PubMedCrossRefGoogle Scholar
  14. 14.
    Koury ME, Regezi JA, Perrott DH, Kaban LB (1995) “Atypical” fibro-osseous lesions: diagnostic challenges and treatment concepts. Int J Oral Maxillofac Surg 24:162–169PubMedCrossRefGoogle Scholar
  15. 15.
    Assaf AT, Benecke AW, Riecke B, Zustin J, Fuhrmann AW, Heiland M et al (2012) Craniofacial fibrous dysplasia (CFD) of the maxilla in an 11-year old boy: a case report. J Craniomaxillofac Surg 40(8):788–792Google Scholar
  16. 16.
    McDonald-Jankowski DS (2004) Fibro-osseous lesions of the face and jaws. Clin Radiol 59:11–25CrossRefGoogle Scholar
  17. 17.
    August M, Faquin WC, Ferraro NF, Kaban LB (1999) Fine-needle aspiration biopsy of intraosseous jaw lesions. J Oral Maxillofac Surg 57:1282–1286PubMedCrossRefGoogle Scholar
  18. 18.
    Parham DM, Bridge JA, Lukacs JL, Ding Y, Tryka AF, Sawyer JR (2004) Cytogenetic distinction among benign fibro-osseous lesions of bone in children and adolescents: value of karyotypic findings in differential diagnosis. Pediatr Dev Pathol 7:148–158PubMedCrossRefGoogle Scholar
  19. 19.
    Pimenta FJ, Gontijo Silveira LF, Tavares GC, Silva AC, Perdigão PF, Castro WH et al (2006) HRPT2 gene alterations in ossifying fibroma of the jaws. Oral Oncol 42:735–739PubMedCrossRefGoogle Scholar
  20. 20.
    Toyosawa S, Yuki M, Kishino M, Ogawa Y, Ueda T, Murakami S et al (2007) Ossifying fibroma vs fibrous dysplasia of the jaw: molecular and immunological characterization. Mod Pathol 20:389–396PubMedCrossRefGoogle Scholar
  21. 21.
    Kolomvos N, Theologie-Lygidakis N, Christopoulos P, Iatrou I (2013) Benign fibro-osseous lesions of the jaws in children. A 12-year retrospective study. J Craniomaxillofac Surg 41(7):574–580PubMedCrossRefGoogle Scholar

Copyright information

© The Association of Oral and Maxillofacial Surgeons of India 2014

Authors and Affiliations

  • K. A. Jeevan Kumar
    • 1
  • P. Krishna Kishore
    • 1
  • A. P. Mohan
    • 1
  • V. Venkatesh
    • 1
  • B. Pavan Kumar
    • 1
  • Divya Gandla
    • 1
  1. 1.Department of Oral and Maxillofacial SurgeryKamineni Institute of Dental SciencesNarketpally, Nalgonda DTIndia

Personalised recommendations