Journal of Maxillofacial and Oral Surgery

, Volume 13, Issue 4, pp 583–591 | Cite as

Randomised Comparative Study on Propofol and Diazepam as a Sedating Agent in Day Care Surgery

  • Amit S. Nirwan
  • Neha JainEmail author
  • Micheal Pragasm
  • Deepashri Kamblimath
  • Anurag Bhargava
  • Saba Tiwari
Comparative Study



The study was conducted to assess the usefulness by qualitative comparison between the two intravenous sedative drugs, Diazepam and Propofol and to provide sedation in apprehensive and uncooperative patients undergoing day care oral surgical procedures.


The present study was conducted on 20 adult patients, 10 in each group (Propofol and Diazepam) irrespective of age and sex. Intravenous sedation of Propofol compared with Diazepam in terms of onset of action, recovery, and anterograde amnesia, patient co-operation, surgeon’s convenience and side effects and other parameters.


Propofol was found to be the superior sedating agent compared to Diazepam, having rapid onset and predictability of action, profoundness of amnesia and a faster recovery period, offering advantages of early patient discharge and better patient compliance.


Propofol was found to be an ideal sedating agent in day care oral surgical procedures.


Propofol Diazepam Sedation 


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Copyright information

© Association of Oral and Maxillofacial Surgeons of India 2013

Authors and Affiliations

  • Amit S. Nirwan
    • 1
  • Neha Jain
    • 2
    Email author
  • Micheal Pragasm
    • 2
  • Deepashri Kamblimath
    • 2
  • Anurag Bhargava
    • 2
  • Saba Tiwari
    • 2
  1. 1.Department of Oral and Maxillofacial SurgeryCollege of Dental Science and HospitalRau, IndoreIndia
  2. 2.Department of Oral and Maxillofacial SurgeryModern Dental College and Research CentreIndoreIndia

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