Journal of Maxillofacial and Oral Surgery

, Volume 11, Issue 2, pp 212–219 | Cite as

OraVerse: Reverses Numbness After Dental Procedures

  • J. S. Prasanna
Review Paper


The lingering numbness that can last anywhere from 3 to 5 h after a routine dental procedure is often an unnecessary, inconvenient hassle. Patients may find that their ability to speak, smile, eat and drink is impaired, and may even have uncontrollable drooling. The effects of local dental anesthetics can now be reversed. That’s because OraVerse, an anesthetic reversal agent, can return the patient to normal sensation and function in about half the time. OraVerse which is U.S. Food and Drug Administration approved is a safe and effective form of phentolamine mesylate, a vasodilator that has been used in several other medical applications since 1952. OraVerse injection – the first and only proven safe and effective product of its kind can quickly reverse the effects of local dental anesthetics, so patient can carry on without impairment of talk, smile and drink after dental procedures. Studies also have shown that there are no known drug interactions and no evident toxicity or contraindications for using OraVerse.


OraVerse Submucosal injection Anaesthesia Periodontal maintenance Reverses numbness 


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Copyright information

© Association of Oral and Maxillofacial Surgeons of India 2012

Authors and Affiliations

  1. 1.Department of PeriodonticsPanineeya Mahavidyalaya Institute of Dental Sciences and Research CentreHyderabadIndia

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