Psychological Studies

, Volume 57, Issue 3, pp 283–291 | Cite as

Theory of Mind Deficit in Schizophrenia and Associated Cognitive Functions

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Abstract

This study examined the Theory of Mind (ToM) ability of schizophrenic persons in association with other cognitive functions like memory, executive functioning and attention. Results showed evidence of relationship between ToM and cognitive functions i.e. executive function, working memory and intelligence but no uniform predictive model was found across all the ToM tasks. It was also noted that predicting variables related to different cognitive domains varied markedly for schizophrenia and control groups. It seems that there are multiple cognitive pathways to ToM mechanism, although these different forms may not have an additive effect.

Keywords

ToM Executive function Working memory Schizophrenia 

Notes

Acknowledgments

I express my gratitude to late Dr. L.M. Sahu for supervising this research work.

References

  1. Baddley, A. D. (1986). Working memory. New York: Oxford University Press.Google Scholar
  2. Baron-Cohen, S., Leslie, A., & Frith, U. (1985). Does the autistic child have a ‘theory of mind’? Cognition, 21, 37–46.PubMedCrossRefGoogle Scholar
  3. Bommer, I., & Brune, M. (2006). Social cognition in pure delusional disorder. Cognitive Neuropsychiatry, 11, 493–503.PubMedCrossRefGoogle Scholar
  4. Bora, E., Eryavuz, A., & Kayahan, B. (2006). Social functioning, theory of mind and neurocognition in outpatients with schizophrenia; mental state decoding may be a better predictor of social functioning than mental state reasoning. Psychiatry Research, 145, 95–103.PubMedCrossRefGoogle Scholar
  5. Bora, E., Sehitoglu, G., Aslier, M., & Atabay, I. (2007). Theory of mind and unawareness of illness in schizophrenia: Is poor insight a mentalizing deficit? European Archives of Psychiatry and Clinical Neuroscience, 257, 104–111.PubMedCrossRefGoogle Scholar
  6. Bora, E., Yucel, M., & Pantelis, C. (2009). Theory of mind impairement in schizophrenia: Meta –analysis. Schizophrenia Research, 109(1–3), 1–9.PubMedCrossRefGoogle Scholar
  7. Botvinick, M., Nystrom, L., Fissell, E., Carter, C. S., & Cohen, J. D. (1999). Conflict monitoring versus selection for action in interior cingulated cortex. Nature, 402, 179–181.PubMedCrossRefGoogle Scholar
  8. Braver, T. S., Barch, D. M., Gray, J. R., Molfese, D. L., & Synder, A. (2001). Anterior cingulated cortex and response conflict: Effects of frequency, inhibition and errors. Cerebral Cortex, 11, 825–836.PubMedCrossRefGoogle Scholar
  9. Brothers, L. (1990). The social brain: A project for integrating primate behavior and neurophysiology in a new domain. Concepts Neuroscience, 1, 27–51.Google Scholar
  10. Brune, M. (2001). Social cognition and psychopathology in an evolutionary perspective-current status and proposal for research. Psychopathology, 34, 85–94.PubMedCrossRefGoogle Scholar
  11. Brune, M. (2003). Theory of mind and the role of IQ in the chronic disorganized schizophrenia. Schizophrenia Research, 60, 57–64.PubMedCrossRefGoogle Scholar
  12. Brüne, M. (2005). Emotion recognition, “theory of mind,” and social behavior in schizophrenia. Psychiatry Research, 133(2–3).Google Scholar
  13. Brune, M. (2005). “Theory of mind” in schizophrenia: A review of the literature. Schizophrenia Bulletin, 31(1), 21–42.PubMedCrossRefGoogle Scholar
  14. Brunet, E., Sarfati, Y., & Hardy-Bayle, M. C. (2003). Abnormalities of brain function during a nonverbal theory of mind task in schizophrenia. Neuropsychologia, 41, 1574–1582.PubMedCrossRefGoogle Scholar
  15. Collette, F., Van der Linden, M., Laureys, S., et al. (2005). Exploring the unity and diversity of the neural substrates of executive functioning. Human Brain Mapping, 25(4), 409–423.PubMedCrossRefGoogle Scholar
  16. Corcoran, R., Mercer, G., & Frith, C. D. (1995). Schizophrenia symptomatology and social inference: Investigating ‘theory of mind’ in people with schizophrenia. Schizophrenia Research, 17, 5–13.Google Scholar
  17. Corcoran, R., & Frith, C. D. (1996). Conversational conduct and symptoms of schizophrenia. Cognitive Neuropsychiatry, 1, 305–318.CrossRefGoogle Scholar
  18. Davis, H. L., & Pratt, C. (1996). The development of children’s theory of mind: The working memory of explanation. Australian Journal of Psychology, 47, 25–31.CrossRefGoogle Scholar
  19. Fisk, J. E., & Sharp, C. A. (2004). Age-related impairment in executive functioning: Updating, inhibition, shifting, and access. Journal of Clinical and Experimental Neuropsychology, 26(7), 874–890.PubMedCrossRefGoogle Scholar
  20. Frith, C. D. (1994). Theory of mind in schizophrenia. In J. C. Cutting & A. S. David (Eds.), The neuropsychology of schizophrenia. Hove: Lawrence Erlbaum Associates.Google Scholar
  21. Frith, C. D., & Corcoran, R. (1996). Exploring theory of mind in people with schizophrenia. Psychological Medicine, 26, 521–530.PubMedCrossRefGoogle Scholar
  22. Gallagher, H. L., Happe, F., Brunswick, N., Fletcher, P. G., Frith, U., & Frith, C. D. (2000). Reading the mind in cartoons and stories: An FMRI study of theory of mind in verbal and non verbal tasks. Neuropsychology, 38, 11–21.CrossRefGoogle Scholar
  23. Gordon, A. C. L., & Olson, D. R. (1998). The relation between acquisition of a theory of mind and the capacity to hold in mind. Journal of Experimental Child Psychology, 68, 70–83.PubMedCrossRefGoogle Scholar
  24. Green, M. F. (1996). What are the functional consequences of neurocognitive deficits in schizophrenia? The American Journal of Psychiatry, 153, 321–330.PubMedGoogle Scholar
  25. Green, M. F., & Nuechterlein, K. H. (1999). Should schizophrenia be treated as a neurocognitive disorder. Schizophrenia Bulletin, 25, 309–318.PubMedCrossRefGoogle Scholar
  26. Hardy-Bayle, M. C., Sarfati, Y., Olivier, V., Besche, C., Lefrere, F., Passerieux, C. (1996). Conscience Intentionnelle et Schizophrenie, 3, 104–107. As cited in Sarfati, Y., Hardy-Bayle, M.C., Nadel, J., Chevalier, J.F., & Widlocher, D. (1997b). Attribution of mental states of others in schizophrenic patients. Cognitive Neuropsychiatry, 2, 1–17.Google Scholar
  27. Heaton, R. K. (1981). Wisconsin card sorting test manual. Odessa: Psychological Assessment Resources.Google Scholar
  28. Hughes, C. (1998). Executive function in preschoolers. Links with theory of mind and verbal ability. British Journal of Developmental Psychology, 16, 233–253.CrossRefGoogle Scholar
  29. Inc, S. P. S. S. (2000). SPSS for windows release 11. Chicago: Standard Edition.Google Scholar
  30. Janssen, I., Krabbendam, L., Jolles, J., & Os, J. V. (2003). Alterations in theory of mind in patients with schizophrenia and non- psychotic relatives. Acta Psychiatrica Scandinavia, 108, 110–117.CrossRefGoogle Scholar
  31. Jha, M. (2010). An exploration of theory of mind in schizophrenic subjects. Indian Journal of Clinical Psychology, 37(2), 88–100.Google Scholar
  32. Kay, S. R., Fisz-Bein, A., & Opler, L. A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261–274.PubMedGoogle Scholar
  33. Keck, P. E., Jr., McElroy, S. L., & Strakowski, S. M. (1998). 12 months outcome of patients with bipolar disorders following hospitalization for a manic or mixed episode. The American Journal of Psychiatry, 155, 646–652.PubMedGoogle Scholar
  34. Kosmidis, M. H., Giannakou, M., Giorgos, G., et al. (2011). The impact of impaired “theory of mind” on social intraction in schizophrenia. Journal of International Neuropsychological Society, 17, 511–521.CrossRefGoogle Scholar
  35. Langdon, R., & Coltheart, M. (2001). Mentalising, executive planning and disengagement in schizophrenia. Cognitive Neuropsychiatry, 6, 81–108.CrossRefGoogle Scholar
  36. Langdon, R., Michie, P., Ward, P. B., et al. (1997). Defective self and/or other mentalising in schizophrenia: A cognitive neuropsychological approach. Cognitive Neuropychiatry, 2, 167–193.CrossRefGoogle Scholar
  37. Langdon, R., Ward, P. B., & Coltheart, M. (2008). Reasonong anamolies associated with delusion in schizophrenia. Schizophrenia Bulletin, 11, 367–384.Google Scholar
  38. Leslie, A. M., & Frith, U. (1988). Autistic children’s understanding of seeing, knowing and believing. British Journal of Developmental Psychology, 6, 315–324.CrossRefGoogle Scholar
  39. Lough, S., Gregory, C., & Hodges, J. R. (2001). Dissociation of social cognition and executive function in frontal variant frontotemporal demential. Neurocase, 7, 123–130.PubMedCrossRefGoogle Scholar
  40. Mandal, M. K., Panday, G., Singh, S. K., & Asthana, H. S. (1992). Hand preferences in India. Indian Journal of Psychiatry, 27, 433–442.Google Scholar
  41. Mitcheley, N. J., Barber, J., Gray, J. M., Brooks, N., & Livingston, M. G. (1998). Comprehension of irony in schizophrenia. Cognitive Neuropsychiatry, 3(2), 127–138.CrossRefGoogle Scholar
  42. Miyake, A., Friedman, N. P., Emerson, M. J., et al. (2000). The unity and diversity of executive functions and their contributions to complex ‘frontal lobe’ tasks: A latent variable analysis. Cognitive Psychology, 41(1), 49–100.PubMedCrossRefGoogle Scholar
  43. Murphy, D. (1998). Theory of mind in a sample of men with schizophrenia detained in a special hospital: Its relationship to symptom profiles and neuropsychological tests. Crime Behaviour Mental Health, 8, 13–26.CrossRefGoogle Scholar
  44. Narr, K. L., Thompson, P. M., & Sharma, T. (2001). A three-dimensional mapping of gyral shape and cortical surface asymmetries in schizophrenia. Gender effects. The American Journal of Psychiatry, 158, 244–255.PubMedCrossRefGoogle Scholar
  45. Perner, J., & Lang, B. (2001). Theory of mind and executive function: Cognitive complexity or functional dependence? In P. D. Zelazo & J. W. Astington (Eds.), Developing theories if intentions: Social understanding and self control. NJ: Erlbaum.Google Scholar
  46. Pershad, D., & Verma, S. K. (1988). PGI battery of brain dysfunction. Agra: National Psychological Corporation.Google Scholar
  47. Pickup, G. J. (2008). Relationship between theory of mind and executive function in schizophrenia: A systematic review. Psychopathology, 41(4), 206–213.PubMedCrossRefGoogle Scholar
  48. Pickup, G. J., & Frith, C. D. (2001). Theory of mind impairments in schizophrenia: Symptomatology, severity and specificity. Psychological Medicine, 31, 207–220.PubMedCrossRefGoogle Scholar
  49. Ramalingaswamy, P. (1974). Manual of Indian adaptation of WAIS–performance scale. Delhi: Manasayan.Google Scholar
  50. Rao, S. L., Subbakrishna, D. K., Gopukumar, K. (2004). NIMHANS neuropsychology battery–2004 manual, NIMHANS, NIMHANS Publication No. 60.Google Scholar
  51. Riley, E. M., McGovern, D., & Mockler, D. (1999). Neuropsychological functioning in first- episode psychosis- evidence of specific deficits. Schizophrenia Research, 43, 47–55.CrossRefGoogle Scholar
  52. Rowe, A. D., Bullock, P. R., Polkey, C. E., & Morris, R. G. (2001). ‘Theory of mind’ impairments and their relationship to executive functioning following frontal lobe excision. Brain, 124, 600–616.PubMedCrossRefGoogle Scholar
  53. Sarfati, Y., Hardy-Baylé, M. C., & Nadel, J. (1997). Attribution of mental states to others in schizophrenic patients. Cognitive Neuropsychiatry, 2, 1–17.CrossRefGoogle Scholar
  54. Sarfati, Y., Hardy Bayle, M. C., Besche, C., & Widlocher, D. (1997). Attributions of intentions to others in people with schizophrenia: A non-verbal exploration with comic-strip. Schizophrenia Research, 25, 199–209.PubMedCrossRefGoogle Scholar
  55. Sarfati, Y., Hardy-Bayle, M. C., Brunet, E., & Widlocher, D. (1999). Investigating theory of mind in schizophrenia: Influence of verbalization in disorganized and non-disorganized patients. Schizophrenia Research, 37, 183–190.PubMedCrossRefGoogle Scholar
  56. Saxe, R., Schulz, L. E., & Jiang, Y. V. (2006). Reading minds versus following rules: Dissociating theory of mind and executive control in the brain. Society for Neuroscience, 1(3–4), 284–298.CrossRefGoogle Scholar
  57. Shallice, T. (1982). Specific impairment of planning. Philosophical Transactions of the Royal Society of London, 298, 199–209.PubMedCrossRefGoogle Scholar
  58. Shamsunder, C., Shanmugam, V., Sriram, T. J., & Murliraj, S. G. (1986). Validity of short 5-item version of the General Health Questionnaire (G.H.Q.). Indian Journal of Psychiatry, 28, 217–219.Google Scholar
  59. Sharma, T., & Antonova, L. (2003). Cognitive functions in schizophrenia. Deficits, functional consequences and future treatment. Psychiatric Clinics of North America, 26, 25–40.PubMedCrossRefGoogle Scholar
  60. Shelton, J. T., Elliott, E. M., Hill, B. D., et al. (2009). A comparison of laboratory and clinical working memory tests and their prediction of fluid intelligence. Intelligence, 37(3), 283–294.PubMedCrossRefGoogle Scholar
  61. Spreen, O., & Strauss, J. (1998). A compendium of neuropsychological tests. Administration, norms and commentary (2nd ed.). New York: Oxford University Press.Google Scholar
  62. Sprong, M., Schothorst, P., & Vos, E. (2007). Theory of mind in schizophrenia: Meta analysis. The British Journal of Psychiatry, 191, 5–13.PubMedCrossRefGoogle Scholar
  63. Stroop, J. R. (1935). Studies on interference in serial verbal reaction. Journal of Experimental Psychology, 18, 643–662.CrossRefGoogle Scholar
  64. Wechsler, D. (1997). Wechsler adult intelligence scale (3rd ed.). San Antonio: The Psychological Corporation.Google Scholar
  65. Whiten, A. (2000). Social complexity and social intelligence. Neurotic Foundation Symposium, 233, 185–196.CrossRefGoogle Scholar
  66. Wimmer, H., & Perner, J. (1983). Belief about beliefs: Representation and the constraining function of wrong beliefs in young childrens’ understanding of deception. Cognitive, 13, 103–128.Google Scholar
  67. World Health Organization. (1993). The ICD-10 classification of mental and behavioural disorders: Diagnostic criteria for research. Geneva: W H O.Google Scholar

Copyright information

© National Academy of Psychology (NAOP) India 2012

Authors and Affiliations

  1. 1.Institute of Human Behaviour and Allied SciencesDelhiIndia

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