Abstract
Intestinal capillariasisis is a newly emerging parasitic disease and its outcome may be fatal if not diagnosed and treated in the proper time. The main diagnosis of intestinal capillariasis is made by identifying eggs, larvae and/or adults in the stools of infected cases. This study aimed to describe a different type of developmental stages, which is the detection of adult females carrying embryonated thick-shelled eggs in their uteri in the fecal samples of infected cases. The study included 40 Capillaria philippinensis patients admitted to the hospitals of Kasr Al-Ainy Faculty of Medicine, Cairo University and Beni-Suef University. Stool examination was performed using direct smear and the formalin-ether concentration methods. The adult stages of the parasite were detected in 35 stool samples, eggs were detected in 33 cases, 5 of them were diagnosed by detecting eggs only. We could identify three types of eggs of C. philippinensis: non-embryonated thick-shelled eggs in feces of cases, embryonated thin-shelled and embryonated thick-shelled eggs in the uteri of female worms. Only in 2 cases we were able to identify female worms with embryonated thick-shelled eggs inside their uteri. This finding has never been mentioned and may point out to a missing point in the known life cycle.
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References
Ahmed L, El-Dib NA, El-Boraey Y, Ibrahim M (1999) Capillaria philippinensis: an emerging parasite causing severe diarrhea in Egypt. J Egypt Soc Parasitol 29:483–493
Amin FMA, El-Dib NA, Mohamed EYA, Aly ME (2014) Clinical and laboratory investigations of cases with Capillaria philippinensis in Beni-Suef Governorate, Egypt. Comp Clin Pathol 23(5):871–878. https://doi.org/10.1007/s00580-014-1999-2
Attia RAH, Tolba MEM, Younes DA, Bakir H, El-Deek HEM, Kamel S (2012) Capillaria philippinensis in upper Egypt: has it become endemic? Am J Trop Med Hyg 86(1):126–133
Belizario VY, de Leon WU, Esparar DG, Galang JM, Fantone J, Verdadero C (2000) Compostela la Valley: a new endemic focus for capillariasis philippinensis. Southeast Asian J Med Public Health 31(3):478–481
Chitwood MB, Velasquez CV, Salazar NP (1964) Physiological changes in a species of capillaria (Trichuroidea) causing a fatal case of human intestinal capillariasis. In: Proceedings of the first international congress of parasitology, Rome
Cross JH (1992) Intestinal capillariasis. Clin Microbiol Rev 5:120–129
Cross JH, Basaca-Sevilla V (1991) Capillaria philippinensis: a fish-borne parasitic zoonosis. Southeast Asian J Trop Med Public Health 22(suppl):153–157
Cross JH, Banzon TC, Murrel KD, Watten RH, Dizon DH (1970) A new epidemic diarrheal disease caused by the nematode, Capillaria philippinensis. Int Trop Health 7:124–131
Cross JH, Banzon TC, Clarke MD, Basaca-Servilla V, Watten RH, Dizon JJ (1972) Studies on the experimental transmission of Capillaria philippinensis in monkeys. Trans R Soc Trop Med Hyg 66(6):819–827
Cross JH, Banzon T, Singson C (1978) Further studies on Capillaria philippinensis: development of the parasite in the Mongolian gerbil. J Parasitol 64:208–213
El-Dib NA, Doss WH (2000) Intestinal capillariasis in Egypt; Epidemiological background. J Egypt Soc Parasitol 32:145–154
El-Dib NA, Ahmed JA, El-Arousy M, Mahmoud MA, Garo K (1999) Parasitological aspects of Capillaria philippinensis recovered from Egyptian patients. J Egypt Soc Parasitol 29:139–147
El-Karaksy H, El-Shabrawi M, Mohsen N, Kotb M, El-Koofy N, El-Deeb N (2004) Capillaria philippinensis: a cause of fatal diarrhea in one of two infected Egyptian sisters. J Trop Pediatr 50:57–60
Methanitikorn R, Sukontason K, Sukontason KL, Piangjai S (2003) Evaluation of the formalin-Tween concentration technique for parasitic detection. Rev Inst Med Trop Sao Paulo 45(5):289–291
Whalen GE, Strickland GT, Cross JH et al (1969) Intestinal capillariasis: a new disease in man. Lancet 1:13–16
Youssef FG, Mikhail EM, Mansour NS (1989) Intestinal capillariasis in Egypt: a case report. Am J Trop Med Hyg 45:195–196
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All procedures performed in the study involving human participants were in accordance with the ethical standards of the Research Ethical Committee of Beni-Suef University, Faculty of Medicine, Egypt. Informed consent was obtained from all individual participants included in the study after explaining the purpose of the study.
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Signed Informed consent (in Arabic) was obtained from the ‘30 years old female’ and from the mother of ‘the 3 years old girl’ after telling them the intention of publication.
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El-Dib, N., Ali, M.I. Can thick-shelled eggs of Capillaria philippinensis embryonate within the host?. J Parasit Dis 44, 666–669 (2020). https://doi.org/10.1007/s12639-020-01248-y
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DOI: https://doi.org/10.1007/s12639-020-01248-y