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Journal of Parasitic Diseases

, Volume 42, Issue 4, pp 630–635 | Cite as

Cryptosporidium infection in chronic kidney disease patients undergoing hemodialysis in Egypt

  • Asmaa M. El-kadyEmail author
  • Yaser Fahmi
  • Mohammed Tolba
  • Abdel-Kader A. Hashim
  • Amal A. Hassan
Original Article

Abstract

Patients with chronic renal failure are more susceptible to infections due to acquired immunodeficiency caused by uremia. Parasitic infections are one of the significant causes of morbidity and mortality in those patients, So we aimed to assess the prevalence of Cryptosporidium spp. and other protozoan infections in patients undergoing hemodialysis in Qena Governorate, Upper Egypt. The present study took place in Qena University Hospitals, Egypt. Participants were 150 Chronic Kidney Disease (CKD) patients undergoing hemodialysis, and 50 healthy individuals. After questionnaire, three consecutive stool samples from each participant were examined macroscopically and microscopically by different techniques for the presence of different stages of different protozoa. 66% of CKD patients and 26% of the control group were infected with intestinal protozoa. Cryptosporidium spp. were the protozoa with the highest prevalence in cases (40%) and control (6%) with statistical significance (P < 0.05). It was detected only in watery stool samples (P value < 0.05). Residence, age and gender were not significant variables in the prevalence of infection among patients with CKD. In Egypt, few studies had reported the prevalence of Cryptosporidiosis in chronic renal patients. Cryptosporidium infection should be suspected in all cases of prolonged watery diarrhea in CKD patients and stool samples should be examined using special stains as cold modified Ziehl–Neelsen staining for proper diagnosis of Cryptosporidium infections.

Keywords

Cryptosporidium Hemodialysis Egypt 

Notes

Author’s contribution

AME and MMT conceived the idea. YF, AME and MMT collected and examined the samples. All authors contributed to the interpretation of the results, preparation of the manuscript and approval the final version of the manuscript.

Compliance with ethical standards

Conflict of interest

All authors declare that they have no conflict of interest.

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Copyright information

© Indian Society for Parasitology 2018

Authors and Affiliations

  1. 1.Department of Medical Parasitology, Faculty of MedicineSouth Valley UniversityQenaEgypt
  2. 2.Department of Medical Parasitology, Faculty of MedicineAssiut UniversityAssiutEgypt
  3. 3.Department of Internal Medicine, Faculty of MedicineSouth Valley UniversityQenaEgypt
  4. 4.Department of Zoology, Faculty of ScienceDamanhour UniversityDamanhûrEgypt

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