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Journal of Parasitic Diseases

, Volume 41, Issue 3, pp 883–887 | Cite as

Surgically managed human cystic echinococcosis in north-eastern Iran: a single center’s experience from 2001 to 2008

  • Mohammad EbrahimipourEmail author
  • Christine M. Budke
  • Mohsen Najjari
  • Kambiz Yaghoobi
Original Article

Abstract

Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by the tapeworm Echinococcus granulosus. Although CE has a large geographic distribution, data are lacking on the frequency of infection and epidemiology of CE in many endemic areas of the world, including the Middle East. Demographic and clinical information on surgically managed human CE cases were evaluated from a referral hospital in north-eastern Iran for the years 2001–2008. Of the 400 CE cases, 218 (54.5%) were male. The median age of patients was 35 years (range 2–83 years). The lungs (41.0%) and liver (37.7%) were the most commonly infected organs. However, 12.7% of patients had multiple organ involvement. The majority of cases (54.3%) were diagnosed using ultrasound, with only 12.0% diagnosed with the help of serology. Total white blood cell count was elevated in 26.8% (107/400) of patients, neutrophil count was elevated in 24.0% (96/400) of patients, and eosinophil count was elevated in 13.3% (53/400) of patients. Lymphocyte count was the only complete blood count (CBC) value that differed based on organ location (P = 0.001). Despite some successes in the control of CE, the number of surgical CE cases in north-eastern Iran remains high. Although not diagnostic alone, CBC values allow for clinicians to obtain a more complete clinical picture of CE before, during, and after treatment. While serology has its place, the use of diagnostic imaging continues to be the most commonly used tool for the diagnosis of CE cases.

Keywords

Cystic echinococcosis (CE) Complete blood count (CBC) Surgery Iran 

Notes

Acknowledgements

The authors would like to express their gratitude to the personnel of Ghaem Hospital in Mashhad County for their useful collaboration.

Compliance with ethical standards

Conflict of interest

The authors declare that there is no conflict of interest.

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Copyright information

© Indian Society for Parasitology 2017

Authors and Affiliations

  • Mohammad Ebrahimipour
    • 1
    Email author
  • Christine M. Budke
    • 2
  • Mohsen Najjari
    • 3
    • 4
  • Kambiz Yaghoobi
    • 3
  1. 1.Department of ParasitologyKerman University of Medical SciencesKermanIran
  2. 2.Department of Veterinary Integrative BiosciencesTexas A&M UniversityCollege StationUSA
  3. 3.Department of Parasitology and Mycology, School of MedicineShiraz University of Medical SciencesShirazIran
  4. 4.Ghaem Educational, Research and Treatment CenterMashhad University of Medical SciencesMashhadIran

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