In the present study, effort to isolate purified GST from Fasciola gigantica homogenate and its early detection for confirmation of infection has been successful. In this study, immunoprotection studies with GST and antibody titer post-infection has revealed GST to be an immunogenic protein with high sensitivity to detect anti-Fasciola antibody as early as two weeks post-infection in large ruminants.
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The authors are thankful to Hon’ble Vice Chancellor, West Bengal University of Animal and Fishery Sciences and the Dean, Faculty of Veterinary and Animal Sciences, WBUAFS for providing the necessary facilities for carrying out this research work.
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Mandal, S., Mukhopadhayay, S.K., Ganguly, S. et al. Immunodiagnosis as an aid for early detection of Fasciola gigantica by glutathione S-transferase (GST). J Parasit Dis 36, 207–209 (2012) doi:10.1007/s12639-012-0106-3
- Fasciola gigantica
- Anti-Fasciola antibody