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Hydroxyethyl starch (HES) utilization before and after a regulatory safety warning

  • Christopher L. PysykEmail author
  • Sylvain Boet
  • Manoj Lalu
  • Alan J. Forster
  • Gregory L. Bryson
Correspondence

Notes

Acknowledgements

Drs. Colleen McFaul, Lauralyn McIntyre, and Monica Taljaard contributed to the original conceptual design of the study and ethics submission. Dr. Daniel McIsaac championed HES removal from the anesthesia drug cart. Mr. Tobin Hess assisted with purchasing and ordering data for hydroxyethyl starch provided to the operating room. Drs. Boet and Lalu were supported by The Ottawa Hospital Anesthesia Alternate Funds Association. Dr. Boet was also supported by the Canadian Anesthesia Research Foundation through the Canadian Anesthesiologists’ Society Career Scientist Award in Anesthesia.

Conflicts of interest

None declared.

Editorial responsibility

This submission was handled by Dr. Hilary P. Grocott, Editor-in-Chief, Canadian Journal of Anesthesia.

References

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    Zarychanski R, Abou-Setta AM, Turgeon AF, et al. Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis. JAMA 2013; 309: 678-88.CrossRefGoogle Scholar
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    Health Canada. Recalls and safety alerts. Voluven and volulyte (hydroxyethyl starch (HES)) – increased mortality and severe renal injury – notice to hospitals. Available from http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/34697a-eng.php (accessed March 2018).
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Copyright information

© Canadian Anesthesiologists' Society 2018

Authors and Affiliations

  • Christopher L. Pysyk
    • 1
    Email author
  • Sylvain Boet
    • 1
  • Manoj Lalu
    • 1
  • Alan J. Forster
    • 2
  • Gregory L. Bryson
    • 3
  1. 1.Department of Anesthesiology and Pain Medicine, The Ottawa HospitalUniversity of OttawaOttawaCanada
  2. 2.Department of Medicine, Ottawa Hospital Research Institute, The Ottawa HospitalUniversity of OttawaOttawaCanada
  3. 3.Clinical Epidemiology Program, Department of Anesthesiology and Pain Medicine, Ottawa Hospital Research InstituteUniversity of OttawaOttawaCanada

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