Les cahiers de l'année gérontologique

, Volume 4, Issue 3, pp 330–344 | Cite as

Évaluation des procédures diagnostiques de la maladie d’Alzheimer : une revue systématique des méta-analyses

  • L. Letrilliart
  • C. Roubaud
  • X. Lainé
  • R. Ecochard
  • P. Krolak-Salmon
Article / Article

Résumé

Cette revue apporte une synthèse des performances diagnostiques des examens cliniques et paracliniques évalués dans le cadre de treize méta-analyses. En soins primaires, l’AMTS est l’examen le plus performant, devant le MMSE, pour diagnostiquer un syndrome démentiel. En soins secondaires, les meilleurs tests cognitifs pour diagnostiquer un syndrome démentiel sont le Mini-Cog, le 6-CIT et le MMSE. L’IRM est performante au stade démentiel pour éliminer le risque d’évolution vers la maladie d’Alzheimer; elle n’a pas été évaluée par une méta-analyse.

Mots clés

Maladie d’Alzheimer Démence Troubles cognitifs légers Diagnostic Dépistage 

Assessment of diagnostic processes for Alzheimer’s disease: a review of meta-analyses

Abstract

This review provides a synthesis of the performances of clinical and complementary tests, as assessed in thirteen meta-analyses. In primary care, the AMTS is the most performing test, before the MMSE, to diagnose a dementia syndrome. In secondary care, the best cognitive tests to diagnose a dementia syndrome are the Mini-Cog, the 6-CIT and the MMSE. The MRI is performing well at the predementia phase to rule out the risk of evolution toward the Alzheimer’s disease; it has not been assessed in a metaanalysis at the dementia phase.

Keywords

Alzheimer’s disease Dementia Mild cognitive impairment Diagnosis Mass-screening 

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Copyright information

© Springer-Verlag France 2012

Authors and Affiliations

  • L. Letrilliart
    • 1
  • C. Roubaud
    • 2
  • X. Lainé
    • 1
  • R. Ecochard
    • 3
  • P. Krolak-Salmon
    • 2
  1. 1.Département de médecine généraleuniversité de Lyon 1Lyon cedex 08France
  2. 2.Centre Mémoire, de Ressources et de Recherche de LyonHôpital des Charpennes, Hospices Civils de LyonLyonFrance
  3. 3.Département de biostatistiquesHospices Civils de LyonLyonFrance

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