Current Considerations of Breast Implant–Associated Anaplastic Large Cell Lymphoma in Breast Surgery: a Systematic Review
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Purpose of Review
A systematic review of three databases (PubMed, Scopus, and Google Scholar) was conducted to appraise the current evidence behind the diagnosis and management of breast implant–associated anaplastic large cell lymphoma (BIA-ALCL). The goal is to help patients make informed decisions regarding reconstruction after breast cancer treatment by educating physicians on the nuances of diagnosis and treatment of BIA-ALCL.
Following recent statements by the FDA, BIA-ALCL has recently garnered the attention of both patients and plastic surgeons. To date, BIA-ALCL has been almost exclusively associated with textured implants.
BIA-ALCL is a very rare T cell lymphoma that was first described more than 20 years ago. BIA-ALCL usually follows an indolent course and carries an excellent prognosis if treated promptly. However, the pathogenesis of the disease is unclear, and further studies need to be conducted to better understand the disease.
KeywordsBreast implant associated anaplastic large cell lymphoma (BIA-ALCL) Anaplastic large cell lymphoma (ALCL) Breast reconstruction Breast cancer Breast implants
Compliance with Ethical Standard
Conflict of Interest
The authors declare that they have no conflicts of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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