Sleep Latency in Men and Sleep Duration in Women Can Be Frailty Markers in Community-Dwelling Older Adults: The Korean Frailty and Aging Cohort Study (KFACS)
To test whether sleep disturbances are associated with frailty in older men and women.
Cross-sectional analysis of cohort study data. The participants were 1168 community-dwelling older adults aged 70 to 84 years who took part in the Korean Frailty and Aging Cohort Study and completed both self-reported sleep parameters and assessment of frailty. Univariate and multivariate survey logistic regression models were used to calculate odds ratios (OR) with 95% confidence intervals (CI) for frailty. Frailty was defined using the Fried’s criteria.
Frailty was associated with sleep latency in men. The odds ratio for this association was 3.39 (95% CI 1.31-8.76) after adjusting for age, body mass index (BMI), physical activity, and select comorbidities, and 2.16 (95% CI 0.75-6.23) after further adjusting for depression. Frailty was associated with long sleep duration of more than 8 hours a night in women. The odds ratio for this association was 3.95 (95% CI, 1.27-12.33) after adjusting for age, BMI, physical activity, select comorbidities, and the number of medications.
Prolonged sleep latency (≥60 minutes) in men and long sleep duration (>8hr per night) in women were each independently associated with higher odds of frailty. Long sleep latency in elderly men and long sleep duration in elderly women may suggest they have a high chance of frailty.
Key wordsSleep latency sleep duration frailty frailty marker Korea
- 1.Ancoli–Israel S, Roth T. Characteristics of insomnia in th. United States: results of the 1991 National Sleep Foundation Survey. I. Sleep. 1999 May 1;22 Suppl 2:S347–53.Google Scholar
- 8.Del Brutto OH, Mera RM, Sedler MJ, Zambrano M, Nieves JL, Cagino K, et al. The effect of age in the association between frailty and poor sleep quality: a populationbased study in community–dwellers (The Atahualpa Project). Journal of the American Medical Directors Association. 2016;17(3):269–71.CrossRefGoogle Scholar
- 13.Lee W, Peng L, Liang C, Chiou S, Chen L. Long sleep duration, independent of frailty and chronic Inflammation, was associated with higher mortality: A national population–based study. Geriatrics & gerontology international. 2017;17(10):1481–7.Google Scholar
- 22.Song HJ, Choi J, Lee YJ, Youn NH, Oh JM, Lee YR. The Association of Objective Depression and Subjective Depression with Weight Change among Korean Adults Aged over 65 Years: Korean National Health and Nutrition Examination Survey, 2010–2012. Korean Journal of Family Practice. 2018;8(2):281–5.CrossRefGoogle Scholar
- 25.Self–reported sleep duration as a predictor of all–cause mortality: results from the JACC study. Japan. Sleep. 2004;27(1):51–4.Google Scholar