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The journal of nutrition, health & aging

, Volume 19, Issue 10, pp 980–985 | Cite as

BMI and body fat mass is inversely associated with vitamin D levels in older individuals

  • S. Oliai Araghi
  • S. C. van Dijk
  • A. C. Ham
  • E. M. Brouwer-Brolsma
  • A. W. Enneman
  • E. Sohl
  • K. M. A. Swart
  • N. L. van der Zwaluw
  • J. P. van Wijngaarden
  • R. A. M. Dhonukshe-Rutten
  • N. M. van Schoor
  • M. C. Zillikens
  • P. Lips
  • L. de Groot
  • A. G. Uitterlinden
  • Nathalie van der VeldeEmail author
Article

Abstract

Objectives

To assess the association between obesity (measured by Body Mass Index (BMI) and fat percentage) and serum 25(OH)D levels in older persons.

Design

Cross-sectional analysis of data from ‘the B-PROOF study’ (B-vitamins for the Prevention Of Osteoporotic Fractures).

Participants

2842 participants aged 65 years and older.

Measurements

BMI and fat percentage, measured by Dual Energy X-ray, and serum 25(OH) D levels.

Results

Mean age was 74 years (6.5 SD), with 50% women. Mean serum 25(OH)D levels were 55.8 nmol/L (25 SD). BMI and total body fat percentage were significant inversely associated with serum 25(OH)D levels after adjustment for confouders (β−0.93; 95%CI [−1.15; −0.71], p<0.001 and β−0.84; 95%CI [−1.04; −0.64], p<0.001). This association was most prominent in individuals with a BMI in the ‘overweight’ and ‘obesity’ range (β−1.25 and −0.96 respectively) and fat percentage in the last two upper quartiles (β−1.86 and −1.37 respectively).

Conclusion

In this study, higher BMI and higher body fat percentage were significantly associated with lower serum 25(OH)D levels in older persons. This association was particularly present in individuals with overweight, and higher fat percentages, suggesting that these persons are at increased risk of vitamin D insufficiency.

Key words

BMI fat percentage vitamin D elderly people 

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Copyright information

© Serdi and Springer-Verlag France 2015

Authors and Affiliations

  • S. Oliai Araghi
    • 1
  • S. C. van Dijk
    • 1
  • A. C. Ham
    • 1
  • E. M. Brouwer-Brolsma
    • 3
  • A. W. Enneman
    • 1
  • E. Sohl
    • 2
  • K. M. A. Swart
    • 2
  • N. L. van der Zwaluw
    • 3
  • J. P. van Wijngaarden
    • 3
  • R. A. M. Dhonukshe-Rutten
    • 3
  • N. M. van Schoor
    • 2
  • M. C. Zillikens
    • 1
  • P. Lips
    • 2
    • 4
  • L. de Groot
    • 3
  • A. G. Uitterlinden
    • 1
    • 5
  • Nathalie van der Velde
    • 1
    • 6
    Email author
  1. 1.Erasmus MC, Department of Internal Medicine, Section of GeriatricsUniversity Medical Centre RotterdamRotterdamthe Netherlands
  2. 2.Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care ResearchVU University Medical CentreAmsterdamthe Netherlands
  3. 3.Division of Human NutritionWageningen UniversityWageningenthe Netherlands
  4. 4.Department of EndocrinologyVU University medical centreAmsterdamthe Netherlands
  5. 5.Department of Epidemiology, Erasmus MCUniversity Medical Centre RotterdamRotterdamthe Netherlands
  6. 6.Department of Internal Medicine, Section of Geriatric MedicineAcademic Medical CentreAmsterdamthe Netherlands

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