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The journal of nutrition, health & aging

, Volume 17, Issue 8, pp 688–693 | Cite as

Promoting access to innovation for frail old persons

IAGG (International Association of Gerontology and Geriatrics), WHO (World Health Organization) and SFGG (Societe Francaise de Geriatrie et de Gerontologie) workshop — Athens January 20–21, 2012
  • G. Berrut
  • S. Andrieu
  • I. Araujo De Carvalho
  • J. P. Baeyens
  • H. Bergman
  • B. Cassim
  • F. Cerreta
  • M. Cesari
  • H. B. Cha
  • L. K. Chen
  • A. Cherubini
  • M. Y. Chou
  • A. J. Cruz-Jentoft
  • L. De Decker
  • P. Du
  • B. Forette
  • F. Forette
  • A. Franco
  • R. Guimaraes
  • L. M. Gutierrez-Robledo
  • J. Jauregui
  • V. Khavinson
  • W. J. Lee
  • L. N. Peng
  • C. Perret-Guillaume
  • M. Petrovic
  • F. Retornaz
  • K. Rockwood
  • L. Rodriguez-Manas
  • C. Sieber
  • G. Spatharakis
  • O. Theou
  • E. Topinkova
  • B. Vellas
  • Athanase Benetos
Article

Abstract

Abstract

Frailty tends to be considered as a major risk for adverse outcomes in older persons, but some important aspects remain matter of debate.

Objectives

The purpose of this paper is to present expert’s positions on the main aspects of the frailty syndrome in the older persons.

Participants

Workshop organized by International Association of Gerontology and Geriatrics (IAGG), World Health Organization (WHO) and Société Française de Gériatrie et de Gérontologie (SFGG).

Results

Frailty is widely recognized as an important risk factor for adverse health outcomes in older persons. This can be of particular value in evaluating non-disabled older persons with chronic diseases but today no operational definition has been established. Nutritional status, mobility, activity, strength, endurance, cognition, and mood have been proposed as markers of frailty. Another approach calculates a multidimensional score ranging from “very fit” to “severely frail,” but it is difficult to apply into the medical practice. Frailty appears to be secondary to multiple conditions using multiple pathways leading to a vulnerability to a stressor. Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.), as well as social factors (isolation, financial situation) are involved in the vulnerability process. In clinical practice, detection of frailty is of major interest in oncology because of the high prevalence of cancer in older persons and the bad tolerance of the drug therapies. Presence of frailty should also be taken into account in the definition of the cardiovascular risks in the older population. The experts of the workshop have listed the points reached an agreement and those must to be a priority for improving understanding and use of frailty syndrome in practice.

Conclusion

Frailty in older adults is a syndrome corresponding to a vulnerability to a stressor. Diagnostic tools have been developed but none can integrate at the same time the large spectrum of factors and the simplicity asked by the clinical practice. An agreement with an international common definition is necessary to develop screening and to reduce the morbidity in older persons.

Key words

Older persons frailty vulnerability diagnostic and workshop 

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Copyright information

© Serdi and Springer-Verlag France 2013

Authors and Affiliations

  • G. Berrut
    • 1
  • S. Andrieu
    • 2
    • 3
  • I. Araujo De Carvalho
    • 4
  • J. P. Baeyens
    • 5
  • H. Bergman
    • 6
  • B. Cassim
    • 7
  • F. Cerreta
    • 8
  • M. Cesari
    • 2
    • 3
  • H. B. Cha
    • 9
  • L. K. Chen
    • 10
  • A. Cherubini
    • 11
    • 12
  • M. Y. Chou
    • 13
  • A. J. Cruz-Jentoft
    • 14
  • L. De Decker
    • 1
  • P. Du
    • 15
  • B. Forette
    • 16
  • F. Forette
    • 17
  • A. Franco
    • 18
  • R. Guimaraes
    • 19
  • L. M. Gutierrez-Robledo
    • 20
  • J. Jauregui
    • 21
  • V. Khavinson
    • 22
  • W. J. Lee
    • 23
  • L. N. Peng
    • 24
  • C. Perret-Guillaume
    • 25
  • M. Petrovic
    • 26
  • F. Retornaz
    • 27
  • K. Rockwood
    • 28
  • L. Rodriguez-Manas
    • 29
  • C. Sieber
    • 30
  • G. Spatharakis
    • 31
  • O. Theou
    • 28
  • E. Topinkova
    • 32
  • B. Vellas
    • 3
    • 33
  • Athanase Benetos
    • 25
    • 34
  1. 1.Pôle Hospitalo-Universitaire de Gérontologie CliniqueCHU NantesNantesFrance
  2. 2.Gérontopole, Service de Santé PubliqueCHU de ToulouseToulouseFrance
  3. 3.INSERM 1027ToulouseFrance
  4. 4.Department of Gender, Women and HealthWorld Health Organization (WHO)GenevaSwitzerland
  5. 5.Department of Geriatric MedicineDamiaan General HospitalOstendBelgium
  6. 6.Department of Family MedicineMc Gill UniversityMontrealCanada
  7. 7.Department of Geriatrics, Nelson R. Mandela School of MedicineUniversity of KwaZulu-NatalDurbanSouth Africa
  8. 8.European Medicines Agency (EMA)LondonUK
  9. 9.Department of Social WelfareHallym UniversityChuncheon, Gangwon-doSouth Korea
  10. 10.Center for Geriatrics and GerontologyTaipei Veterans General HospitalTaipeiTaiwan
  11. 11.GeriatricsIRCCS-INRCAAnconaItaly
  12. 12.Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, Policlinico Santa Maria della MisericordiaUniversity of Perugia Medical SchoolPerrugiaItaly
  13. 13.Geriatric Medicine CenterKaohsiung Veterans General HospitalKaohsiung CityTaiwan
  14. 14.Geriatric DepartmentHospital Universitario Ramón y CajalMadridSpain
  15. 15.Academic Research OfficeRemnin UniversityBeijingChina
  16. 16.Hôpital Sainte PerrineParisFrance
  17. 17.ILC-International Longevity CenterParisFrance
  18. 18.Département de Médecine GériatriqueCHU de NiceNiceFrance
  19. 19.School of Health SciencesBrasíliaBrazil
  20. 20.Instituto Nacional de GeriatríaMexico CityMexico
  21. 21.Hospital ItalianoBuenos AiresArgentina
  22. 22.St Petersburg Institute of Bioregulation and GerontologySt PetersburgRussia
  23. 23.Division of Geriatric MedicineTaipei Veterans General Hospital, Yuanshan BranchI-LanTaiwan
  24. 24.Division of Geriatric Medicine, Center for Geriatrics and GerontologyTaipei Veterans General HospitalTaipeiTaiwan
  25. 25.Département de Médecine GériatriqueCHU de NancyVandoeuvre les NancyFrance
  26. 26.Department of GeriatricsGhent University HospitalGhentBelgium
  27. 27.Centre Gérontologique DépartementalMarseilleFrance
  28. 28.Department of MedicineDalhousie UniversityHalifaxCanada
  29. 29.Department of GeriatricsHospital Universitario de GetafeMadridSpain
  30. 30.Friedrich-Alexander-UniversityErlangen-NuernbergGermany
  31. 31.Public Primary Health Center of IteaPhokidaGreece
  32. 32.Department of Geriatrics, First Faculty of MedicineCharles UniversityPragueCzech Republic
  33. 33.Gérontopôle, Service de Médecine Interne GériatriqueCHU ToulouseToulouseFrance
  34. 34.Département de Médecine GériatriqueCHU de NancyVandoeuvre-les-NancyFrance

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