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The journal of nutrition, health & aging

, Volume 15, Issue 10, pp 896–900 | Cite as

Dietary antioxidant intake is associated with the prevalence but not incidence of age-related hearing loss

  • B. Gopinath
  • V. M. Flood
  • C. M. McMahon
  • G. Burlutsky
  • C. Spankovich
  • L. J. Hood
  • Paul MitchellEmail author
Anti-Oxidants and Hearing Loss

Abstract

Objectives

Diet is one of the few modifiable risk factors for age-related hearing loss. We aimed to examine the link between dietary and supplement intakes of antioxidants, and both the prevalence and 5-year incidence of measured hearing loss.

Design

Cross-sectional and 5-year longitudinal analyses. Setting: Blue Mountains, Sydney, Australia.

Participants

2,956 Blue Mountains Hearing Study participants aged 50+ at baseline, examined during 1997–9 to 2002–4.

Measurements

Age-related hearing loss was measured and defined as the pure-tone average of frequencies 0.5, 1.0, 2.0 and 4.0 kHz >25 dB HL. Dietary data were collected in a semi-quantitative food frequency questionnaire, and intakes of -carotene; -carotene; -cryptoxanthin; lutein and zeaxanthin; lycopene; vitamins A, C and E; iron and zinc were calculated.

Results

After adjusting for age, sex, smoking, education, occupational noise exposure, family history of hearing loss, history of diagnosed diabetes and stroke, each standard deviation (SD) increase in dietary vitamin E intake was associated with a 14% reduced likelihood of prevalent hearing loss, odds ratio, OR, 0.86 (95% confidence interval, CI, 0.78–0.98). Those in the highest quintile of dietary vitamin A intake had a 47% reduced risk of having moderate or greater hearing loss (>40 dB HL) compared to those in the lowest quintile of intake, multivariable-adjusted OR 0.53 (CI 0.30–0.92), P for trend = 0.04. However, dietary antioxidant intake was not associated with the 5-year incidence of hearing loss.

Conclusions

Dietary vitamin A and vitamin E intake were significantly associated with the prevalence of hearing loss. However, dietary antioxidant intake did not increase the risk of incident hearing loss. Further large, prospective studies are warranted to assess these relationships in older adults.

Key words

Age-related hearing loss antioxidant vitamin A vitamin E Blue Mountains Eye Study Blue Mountains Hearing Study 

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Copyright information

© Serdi and Springer Verlag France 2011

Authors and Affiliations

  • B. Gopinath
    • 1
    • 2
  • V. M. Flood
    • 3
  • C. M. McMahon
    • 4
    • 5
  • G. Burlutsky
    • 1
  • C. Spankovich
    • 6
  • L. J. Hood
    • 6
  • Paul Mitchell
    • 1
    • 7
    Email author
  1. 1.Centre for Vision Research, Department of Ophthalmology and Westmead Millennium InstituteUniversity of SydneySydneyAustralia
  2. 2.Menzies Centre for Health PolicyUniversity of SydneySydneyAustralia
  3. 3.University of WollongongSydneyAustralia
  4. 4.Centre for Language Sciences, Linguistics DepartmentUniversity of MacquarieSydneyAustralia
  5. 5.HEARing Co-operative Research CentreSydneyAustralia
  6. 6.Department of Hearing and Speech SciencesVanderbilt UniversityNashvilleUSA
  7. 7.Centre for Vision ResearchUniversity of Sydney, Westmead HospitalWestmeadAustralia

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