The journal of nutrition, health & aging

, Volume 15, Issue 6, pp 433–438

Thigh muscle volume predicted by anthropometric measurements and correlated with physical function in the older adults

  • B. -B. Chen
  • T. T. F. Shih
  • C. -Y. Hsu
  • C. -W. Yu
  • S. -Y. Wei
  • C. -Y. Chen
  • C. -H. Wu
  • Ching-Yu Chen
JNHA: Nutrition

DOI: 10.1007/s12603-010-0281-9

Cite this article as:
Chen, B.B., Shih, T.T.F., Hsu, C.Y. et al. J Nutr Health Aging (2011) 15: 433. doi:10.1007/s12603-010-0281-9

Abstract

Objectives

1) to correlate thigh muscle volume measured by magnetic resonance image (MRI) with anthropometric measurements and physical function in elderly subjects; 2) to predict MRI-measured thigh muscle volume using anthropometric measurements and physical functional status in elderly subjects.

Design

Crosssectional, nonrandomized study.

Setting

Outpatient clinic in Taiwan.

Participants

Sixty-nine elderly subjects (33 men and 36 women) aged 65 and older.

Measurments

The anthropometric data (including body height, body weight, waist size, and thigh circumference), physical activity and function (including grip strength, bilateral quadriceps muscle power, the up and go test, chair rise, and five meters walk time) and bioelectrical impedance analysis data (including total body fat mass, fat-free mass, and predictive muscle size) were measured. MRI-measured muscle volume of both thighs was used as the reference standard.

Results

The MRI-measured thigh volume was positively correlated with all anthropometric data, quadriceps muscle power and the up and go test as well as fat-free mass and predictive muscle mass, whereas it was negatively associated with age and walk time. In predicting thigh muscle volume, the variables of age, gender, body weight, and thigh circumference were significant predictors in the linear regression model: Muscle volume(cm3) =4226.3−42.5×Age(year)−955.7×gender(male=1, female=2)+45.9×body weight(kg) +60.0×thighcircumference (cm) (r2 = 0.745, P < 0.001; Standard Error of the Estimate = 581.6cm3).

Conclusion

The current work provides evidence of a strong relationship between thigh muscle volume and physical function in the elderly. We also developed a prediction equation model using anthropometric measurements. This model is a simple and noninvasive method for everyday clinical practice and follow-up.

Key words

Muscle volume magnetic resonance imaging elderly 

Copyright information

© Serdi and Springer Verlag France 2011

Authors and Affiliations

  • B. -B. Chen
    • 1
  • T. T. F. Shih
    • 2
  • C. -Y. Hsu
    • 2
  • C. -W. Yu
    • 2
  • S. -Y. Wei
    • 2
  • C. -Y. Chen
    • 3
  • C. -H. Wu
    • 4
  • Ching-Yu Chen
    • 3
    • 4
    • 5
  1. 1.Departments of Medical Imaging and RadiologyNational Taiwan University Hospital and National Taiwan University, college of medicine, Yun-Lin BranchTaipeiTaiwan
  2. 2.Departments of Medical Imaging and RadiologyNational Taiwan University Hospital and National Taiwan University, College of MedicineTaipeiTaiwan
  3. 3.Department of Family MedicineNational Taiwan University Hospital and National Taiwan University, College of MedicineTaipeiTaiwan
  4. 4.Division of Geriatric research, Institute of Population Health SciencesNational Health Research InstitutesTaipeiTaiwan
  5. 5.Division of Geriatric Research, Institute of Population Health SciencesNational Health Research InstitutesTaipeiTaiwan

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