The journal of nutrition, health & aging

, Volume 15, Issue 5, pp 327–331 | Cite as

Association of osteoporotic fracture with smoking, alcohol consumption, tea consumption and exercise among Chinese nonagenarians/centenarians

  • F. Du
  • H. Qiukui
  • Dong BirongEmail author
  • H. Changquan
  • W. Hongmei
  • Z. Yanling
  • Z. Wen
  • L. Li
JNHA: Nutrtion



To observe the association of osteoporotic fracture with habits of smoking, alcohol consumption, tea consumption and exercise among very old people.

Design and setting

A cross sectional study conducted in Dujiangyan Sichuan China.


703 unrelated Chinese nonagenarians and centenarians (67.7(1% women, mean age 93.48 years) resident in Dujiangyan.


Medical history of osteoporosis and the statement of fracture and habits (current and former) of smoking, alcohol consumption, tea consumption and exercise were collected.


In women, subjects with current or former habit of alcohol consumption had significantly higher prevalence osteoporotic fracture than those without this habit; but subjects with former habit of exercise had significantly lower prevalence osteoporotic fracture than those without tills habit. However, in men, there was no significant difference in prevalence of these habits between subjects with and without osteoporotic fracture. After adjust for age, gender, sleep habits educational levels, religion habits and temperament, we found that former habit of alcohol consumption had a significant odds ratio (OR=2.473 95% CI (1.074, 5.526)) for osteoporotic fracture.


In summary, among nonagenarians and centenarians, among habits (current and former) of smoking, alcohol consumption, tea consumption and exercise, there seems to be significant association of osteoporotic fracture only with current or former habits of alcohol consumption, former habit of exercise. The habit of alcohol consumption might be associated with a greater risk of osteoporotic fracture, but the former habit of exercise might be associated with a lower risk of osteoporotic fracture.

Key words

Osteoporotic fracture smoking alcohol consumption exercise nonagenarians/centenarians 


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  1. 1.
    Cooper C. Epidemiology of osteoporosis. Osteoporos Int 1999; 9Suppl 2: S2–S8. [PubMed:10525719]PubMedCrossRefGoogle Scholar
  2. 2.
    Johnell O. Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 2006; 17(12); 1726–1733. [PubMed: 16983459]PubMedCrossRefGoogle Scholar
  3. 3.
    Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet 2002; 359(9319): 1761–1767. [PubMed:12049882]PubMedCrossRefGoogle Scholar
  4. 4.
    Reginster JY, Burlet N. Osteoporosis: a still increasing prevalence. Bone 2006; 38(2 Suppl 1): S4–S9. [PubMed: 16455317]PubMedCrossRefGoogle Scholar
  5. 5.
    Liu JM, Ning G, Chen JL Osteoporotic fractures in Asia risk factors and strategies for prevention. J Bone Miner Metab 2007; 25(1): 1–5. [PubMed:17187187]PubMedCrossRefGoogle Scholar
  6. 6.
    Sakuma M, F-ndo N, Oinuma T et al. Incidence and outcome of osteoporotic fractures in 2004 in Sado City, Niigata Prefecture, Japan. J Bone Miner Metab 2008; 26(4): 373–378. [PubMed: 18600404]PubMedCrossRefGoogle Scholar
  7. 7.
    Shen CL, Yeh JK, Cao JJ et al. Green tea and bone metabolism. Nutr Res 2009; 29(7): 437–456. [PubMed: 19700031]PubMedCrossRefGoogle Scholar
  8. 8.
    Hallstrorn H, Wolk A, Glynn A et al. Coffee, tea and caffeine consumption in relation to osteoporotic fracture risk in a cohort of Swedish women. Osteoporos Int 2006; 17(7): 1055–1064. PubMed:16758142]CrossRefGoogle Scholar
  9. 9.
    Kanis JA, Johnell O, Oden A et al. Smoking and fracture risk: a meta analysis. Osteoporos Int 2005; 16(2): 155–162. [PubMed: 15175845]PubMedCrossRefGoogle Scholar
  10. 10.
    Vestergaard P, Mosekilde L. Fracture risk associated with smoking: a met a-analysis. J Intern Med 2003; 254(6): 572–583. [PubMed:14641798]PubMedCrossRefGoogle Scholar
  11. 11.
    Berg KM. Kunins HV, Jackson JL et al. Association between alcohol consumption and both osteoporotic fracture and bone density. Am J Med 2008; 121(5): 406–418. PubMed:18456037]PubMedCrossRefGoogle Scholar
  12. 12.
    Mukamal KT, Robbins JA, Cauley JA et al. Alcohol consumption, bone density, and hip fracture among older adults: the cardiovascular health study. Osteoporos Int 2007; 18(5): 593–602. [PubMed:17318666]PubMedCrossRefGoogle Scholar
  13. 13.
    Hourigan SR, Nitz JC, Brauer SG et al. Positive effects of exercise on falls and fracture risk in osteopenic women. Osteoporos Int 2008; 19(7); 1077–1086. [PubMed: 18188658]PubMedCrossRefGoogle Scholar
  14. 14.
    Yoshimura N. Exercise and physical activities for the prevention of osteoporotic fractures: a review of the evidence. Nippon Eiseigaku Zasshi 2003; 58(3): 328–337. [PubMed: 14533562]PubMedGoogle Scholar
  15. 15.
    Pecina M, Smoljanovic T, Cicvara-Pecina T et al. Osteoporotic fractures in the elderly. Arh Hig RadaToksikol 2007; 58(1): 41–47. [PubMed: 17424784]Google Scholar
  16. 16.
    Aoyagi K. Osteoporosis and osteoporotic fractures in the elderly. Acta Medica Nagasakiensia 2004; 49(1–2): 7–11.Google Scholar
  17. 17.
    Holrovd C, Cooper C, Dennison E. Epidemiology of osteoporosis. Best Praet Res Clin Endocrinol Metab 2008; 22(5): 671–685. [PubMed: 19028351]CrossRefGoogle Scholar
  18. 18.
    Cummings SR, Kelsey TL, Nevitt MC et al. Epidemiology of osteoporosis and osteoporotic fractures. Epidemiol Rev 1985; 7: 178–208. [PubMed3902494]PubMedGoogle Scholar
  19. 19.
    Jutberger H, Lorentzon M, Barrett-Connor E et al. Smoking Predicts Incident Fractures in Elderly Men: Mr OS Sweden. J Bone Miner Res 2009. [PubMed: 19929437]Google Scholar
  20. 20.
    Jenkins MR, Denison AY. Smoking status as a predictor of hip fracture risk in postmenopausal women of northwest Texas. Prev Chronic Dis 2008; 5(1): A09. [PubMed: 18081998]PubMedGoogle Scholar
  21. 21.
    Olofsson H, Byberg L., Mohsert R et al. Smoking and the risk of fracture in older men. J Bone Miner Res 2005; 20(7): 1208–1215. [PubMed: 15940374]PubMedCrossRefGoogle Scholar
  22. 22.
    Hioidrup S, Prescott EI, Sorensen TI et al. Tobacco smoking and risk of hip fracture in men and women. Results from the Hovedstadens Center for Prospective Population Studies. Ugeskr Laeger 2001; 163(40): 5532–5536. [PubMed:11601121]Google Scholar
  23. 23.
    Baron JA, Farahmand BY, Weiderpass E et al. Cigarette smoking, alcohol consumption, and risk of hip fracture in women. Arch Intern Med 2001; 161(7): 983–988. [PubMed:11295961]PubMedCrossRefGoogle Scholar
  24. 24.
    Hoidrop S, Prescott E, Sorensen TI et al. Tobacco smoking and risk of hip fracture in men and women. Int J Epidemiol 2000; 29(2): 253–259. [PubMed:10817121]CrossRefGoogle Scholar
  25. 25.
    Hemenway D, Colditz GA, Willett WC et al. Fractures and lifestyle: effect of cigarette smoking, alcohol intake, and relative weight on the risk of hip and forearm fractures in middle-aged women. Am J Public Health 1988; 78(12): 1554–1558. [PubMed:3189632]PubMedCrossRefGoogle Scholar
  26. 26.
    Hoidrop S, Gronbaek M, Gottschau A et al. Alcohol intake, beverage preference, and risk of hip fracture in men and women. Copenhagen Centre for Prospective Population Studies. Am J Epidemiol 1999; 149(11): 993–1001. [PubMed: 10355374]Google Scholar
  27. 27.
    Felson DT, Zhang Y, Hannan MT et al. Alcohol intake and bone mineral density in elderly men and women. The Framingham Study. Am J Epidemiol 1995; 142(5): 485–492. [PubMed:7677127]PubMedGoogle Scholar
  28. 28.
    Cawthon PM, Harrison SL, Barrett-Connor E et al. Alcohol intake and its relationship with bone mineral density, falte, and fracture risk in older men. J Am GeriatrSoc 2006; 54(11): 1649–1657. [PubMed: 17087690]CrossRefGoogle Scholar
  29. 29.
    Kogawa M. Wada S. [Osteoporosis and alcohol intake.]. Clin Calcium 2005; 15(1): 102–105. [PubMed: 15632479]PubMedGoogle Scholar
  30. 30.
    Chen Z, Pettinger MB, Ritenbaugh C et al. Habitual tea consumption and risk of osteoporosis: a prospective study in the women’s health initiative observational cohort. Am J Epidemiol 2003; 158(8): 772–781. [PubMed:14561667]PubMedCrossRefGoogle Scholar
  31. 31.
    Devine A, Hodgson JM. Dick IM et al. Tea drinking is associated with benefits on bone density in older women. Am J Clin Nutr 2007; 86(4): 1243–1247. [PubMed:17921409]PubMedGoogle Scholar
  32. 32.
    Cabrera C, Gimenez R, Lopez MC. Determination of tea components with antioxidant activity. J Agric Food Chem 2003; 51(15): 4427–4435. [PubMed: 12848521]PubMedCrossRefGoogle Scholar
  33. 33.
    Gusi N, Raimundo A, Leal A. Low-frequency vibratory exercise reduces the risk of bone fracture more than walking: a randomized controlled trial. BMC Musculoskelet Disord 2006; 7: 92. [PubMed:17137514]PubMedCrossRefGoogle Scholar
  34. 34.
    Lord SR, Ward JA, Williams P et al. The effects of a community exercise program on fracture risk factors in older women. Osteoporos Int 1996; 6(5): 361–367. [PubMed:8931030]PubMedCrossRefGoogle Scholar
  35. 35.
    Heinonen A, Kannus P, Sievanen H el al. Randomised controlled trial of effect of high-imp act exercise on selected risk factors for osteoporotic fractures. Lancet 1996; 348(9038): 1343–1347. [PubMed:8918277]PubMedCrossRefGoogle Scholar
  36. 36.
    Sakamoto K, Nakamura T, Hagino H et al. Effects of unipedal standing balance exercise on the prevention of falls and hip fracture among clinically defined high-risk elderly individuals: a randomized controlled trial. J Ortbop Sci 2006; 11(5): 467–472. [PubMed:17013734]CrossRefGoogle Scholar
  37. 37.
    Kerschan-bhindl K, Uher E, Kainberger F et al. Long-term home exercise program: effect in women at high risk of fracture. Arch Phys Med Rehabil 2000; 81(3): 319–323. [PubMed:10724077]CrossRefGoogle Scholar

Copyright information

© Serdi and Springer Verlag France 2011

Authors and Affiliations

  • F. Du
    • 1
  • H. Qiukui
    • 1
  • Dong Birong
    • 1
    Email author
  • H. Changquan
    • 1
  • W. Hongmei
    • 1
  • Z. Yanling
    • 1
  • Z. Wen
    • 1
  • L. Li
    • 1
  1. 1.Department and institution Department of Geriatrics, West China HospitalSichuan UniversityChenduChina

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