The journal of nutrition, health & aging

, Volume 14, Issue 3, pp 203–206 | Cite as

Non-pharmacologic management of sleep disturbance in Alzheimer’s disease

  • R. David
  • J. Zeitzer
  • L. Friedman
  • A. Noda
  • R. O’hara
  • P. Robert
  • Jerome A. YesavageEmail author
JNHA: Clinical Neurosciences


Sleep and wake in Alzheimer’s disease (AD) are often fragmented as manifested by bouts of wakefulness at night and napping during the day. Management of sleep disturbances in AD is important because of their negative impact on both patients and caregivers. Pharmacological treatments, mainly sedative-hypnotics and antipsychotics, are often used but can be associated with significant adverse effects. Non-pharmacological treatments represent a beneficial alternative approach to the management of sleep disturbances in AD since they are associated with fewer adverse effects and their efficacy can be sustained after treatment has been completed. The aim of this article is to review non-pharmacological treatments, such as sleep hygiene, sleep restriction therapy (SRT), cognitive behavioral therapy (CBT), light therapy, and continuous positive airway pressure (CPAP), for the management of sleep/wake disturbances in AD.

Key words

Alzheimer’s disease sleep/wake disturbances circadian Rhythm 


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Copyright information

© Serdi and Springer Verlag France 2010

Authors and Affiliations

  • R. David
    • 3
  • J. Zeitzer
    • 1
    • 2
  • L. Friedman
    • 2
  • A. Noda
    • 2
  • R. O’hara
    • 1
    • 2
  • P. Robert
    • 3
  • Jerome A. Yesavage
    • 1
    • 2
    • 4
    Email author
  1. 1.Department of Veterans Affairs Health Care SystemPalo AltoUSA
  2. 2.Department of Psychiatry and Behavioral SciencesStanford University School of MedicineStanfordUSA
  3. 3.Memory Center (CMRR)CIU-S, CHU de NiceNiceFrance
  4. 4.VA Health Care System (151Y)Palo AltoUSA

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