Probiotics and Antimicrobial Proteins

, Volume 8, Issue 4, pp 177–182 | Cite as

Bacteriocins: Not Only Antibacterial Agents

  • Djamel Drider
  • Farida Bendali
  • Karim Naghmouchi
  • Michael L. Chikindas


This commentary was aimed at shedding light on the multifunction of bacteriocins mainly those produced by lactic acid bacteria. These antibacterial agents were first used to improve food safety and quality. With the increasing antibiotic resistance concern worldwide, they have been considered as viable agents to replace or potentiate the fading abilities of conventional antibiotics to control human pathogens. Bacteriocins were also shown to have potential as antiviral agents, plant protection agents, and anticancer agents. Bacteriocins were reported to be involved in shaping bacterial communities through inter- and intra-specific interactions, conferring therefore to producing strains a probiotic added value. Furthermore, bacteriocins recently were shown as molecules with a fundamental impact on the resilience and virulence of some pathogens.


Bacteriocins Multifunction Activities 


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Djamel Drider
    • 1
  • Farida Bendali
    • 2
  • Karim Naghmouchi
    • 3
  • Michael L. Chikindas
    • 4
    • 5
  1. 1.Univ. Lille, INRA, ISA, Univ. Artois, Univ. Littoral Côte d’OpaleEA 7394 – ICV - Institut Charles ViolletteLilleFrance
  2. 2.Laboratoire de Microbiologie Appliquée, Faculté des Sciences de la Nature et de la VieUniversité de BejaiaBejaïaAlgeria
  3. 3.Laboratoire des Microorganismes et Biomolécules Actives (LMBA), Faculté des Sciences de TunisUniversité El-Manar II 2092 El-Manar-IITunisTunisia
  4. 4.School of Environmental and Biological SciencesRutgers State UniversityNew BrunswickUSA
  5. 5.Center for Digestive HealthNew Jersey Institute for Food, Nutrition and HealthNew BrunswickUSA

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