Ia excitation and recurrent inhibition are basic neuronal circuits in motor control in hind limb. Renshaw cells receive synaptic inputs from axon collaterals of motoneurons and inhibit motoneurons and Ia inhibitory interneurons. It is important to know properties of Ia excitation and recurrent inhibition of trunk muscle such as abdominal muscles. The abdominal muscles have many roles and change those roles for different kind of functions. Intracellular recordings were obtained from the abdominal motoneurons of the upper lumbar segments in cats anesthetized. First, dorsal roots were left intact, and sensory and motor axons were electrically stimulated. Ia excitatory post-synaptic potentials were elicited in five of eight motoneurons at same segment stimulated. Second, dorsal roots were sectioned, and motor axons were electrically stimulated. Recurrent inhibitory post-synaptic potentials were elicited in one of 11 abdominal motoneurons. Renshaw cells extracellularly fired high-frequency bursts at short latency and at same segment stimulated.
This is a preview of subscription content, log in to check access.
This study was supported by a KAKENHI grant (25350621) from the Japan Society for the Promotion of Science. We would also like to thank Editage (www.editage.jp) for English language editing.
All co-authors participated in data collection and analysis. All co-authors have read and approved the final manuscript.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflicts of interest.
All experimental procedures were approved by the Animal Ethics Committee of Ibaraki Prefectural University of Health Sciences and were in accordance with the guiding principles for care and use of animals in the field of physiological sciences outlined by the Physiological Society of Japan.
Niwa M, Muramatsu K, Sasaki S-I (2015) Discharge patterns of abdominal and pudendal nerves during induced defecation in anesthetized cats. J Physiol Sci 65:223–231CrossRefGoogle Scholar
Waters RL, Morris JM (1972) Electrical activity of muscles of the trunk during walking. J Anat 111:191–199Google Scholar
De Troyer A (1983) Mechanical role of the abdominal muscles in relation to posture. Respir Physiol 53:341–353CrossRefGoogle Scholar
Miller AD, Tan LK, Suzuk I (1987) Control of abdominal and expiratory intercostal muscle activity during vomiting: role of ventral respiratory group expiratory neurons. J Neurophysiol 57:1854–1866CrossRefGoogle Scholar
Bishop B (1964) Reflex control of abdominal muscles during positive pressure breathing. J Appl Physiol 19:224–232CrossRefGoogle Scholar
Russel JA, Beverly P, Bishop BP, Hyatt RE (1987) Discharge of abdominal muscle α and γ motoneurons during expiratory loading in cats. Exp Neurol 97:179–192CrossRefGoogle Scholar
Niwa M, Nakayama K, Sasaki S-I (2008) Morphological study of external oblique motor nerves and nuclei in cats. Anat Sci International 83:17–25CrossRefGoogle Scholar
Lloyd DPC (1943) Conduction and synaptic transmission of the reflex response to stretch in spinal cats. J Neurophysiol 6:317–326CrossRefGoogle Scholar
Lloyd DPC (1943) Reflex action in relation pattern and peripheral source of afferent stimulation. J Neurophysiol 6:111–119CrossRefGoogle Scholar
Eccles JC, Eccles RM, Lundberg A (1957) Synaptic actions on motoneurones in relation to the two components of the group I muscle afferent volley. J Physiol 136:527–546CrossRefGoogle Scholar
Sears TA (1964) Some properties and reflex connections of respiratory motoneurones of the cat’s thoracic spinal cord. J Physiol 175:386–403CrossRefGoogle Scholar
Eccles JC, Fatt P, Koketsu K (1954) Cholinergic and inhibitory synapses in a pathway from motor-axon collaterals to motoneurons. J Physiol 126:524–562CrossRefGoogle Scholar
Eccles JC, Eccles RM, Iggo A, Lundberg A (1961) Electrophysiological investigations of Renshaw cells. J Physiol 159:461–478CrossRefGoogle Scholar
Kirkwood PA, Sears TA, Westgaard RH (1981) Recurrent inhibition of intercostal motoneurons in the cats. J Physiol 319:111–130CrossRefGoogle Scholar
Brink EE, Suzuki I (1987) Recurrent inhibitory connexions among neck motoneurones in the cat. J Physiol 383:301–326CrossRefGoogle Scholar
Hilaire G, Khatib M, Monteau R (1986) Central drive on Renshaw cells coupled with phrenic motoneurons. Brain Res 376:133–139CrossRefGoogle Scholar
Gill PK, Kuno M (1963) Excitatory and inhibitory actions on phrenic motoneurones. J Physiol 168:274–289CrossRefGoogle Scholar
Uga M, Niwa M, Ochiai N, Sasaki S-I (2010) Activity pattern of the diaphragm during voluntary movements in awake cats. J Physiol Sci 60:173–180CrossRefGoogle Scholar
Ishizuka N, Mannen H, Hongo T, Sasaki S (1979) Trajectory of group Ia afferent fibres stained with horseradish peroxidase in the lumbosacral spinal cord of the cat: three-dimensional reconstructions from serial sections. J Comp Neurol 186:189–211CrossRefGoogle Scholar
Nakayama K, Niwa M, Sasaki S-I, Ichikawa T, Hirai N (1998) Morphology of single primary spindle afferents of the intercostal muscles in the cat. J Comp Neurol 398:459–472CrossRefGoogle Scholar
Eccles RM, Sears TA, Shealy CN (1962) Intra-cellular recording from respiratory motoneurones of the thoracic spinal cord of the cat. Nature 193:844–846CrossRefGoogle Scholar
Eccles JC, Eccles RM, Lundberg A (1958) The action potentials of the alpha motoneurones supplying fast and slow muscles. J Physiol 142:275–291CrossRefGoogle Scholar
McCurdy ML, Hamm T (1992) Recurrent collaterals of motoneurons projecting to distal muscles in the cat hindlimb. J Neurophysiol 67:1359–1366CrossRefGoogle Scholar
Illert M, Wietelmann D (1989) Distribution of recurrent inhibition in the cat forelimb. Prog Brain Res 80:273–281CrossRefGoogle Scholar
Jankowska E, Odutola A (1980) Crosses and uncrossed synaptic actions on motoneurones of back muscles in the cat. Brain Res 194:65–78CrossRefGoogle Scholar
Jankowska E, Lindström S (1971) Morphological identification of Renshaw cells. Acta Physiol Scand 81:428–430CrossRefGoogle Scholar
Cullhem S, Kellerth J-O (1978) A morphological study of the axons and recurrent axon collaterals of cat sciatic a-motoneurons after intracellular staining with horseradish peroxidase. J Comp Neurol 178:537–558CrossRefGoogle Scholar
Hilaire G, Khatib M, Monteau R (1983) Spontaneous respiratory activity of phrenic and intercostal Renshaw cells. Neurosci Lett 43:97–101CrossRefGoogle Scholar
Hultborn H, Lindstrom S, Wigstrom H (1979) On the function of recurrent inhibition in the spinal cord. Exp Brain Res 37:399–403CrossRefGoogle Scholar
Hultborn H, Jankowska E, Lindstrom S (1971) Recurrent inhibition from motor axon collaterals of transmission in the Ia inhibitory pathway to motoneurones. J Physiol 215:591–612CrossRefGoogle Scholar
Hultborn H, Jankowska E, Lindstrom S (1971) Recurrent inhibition of interneurones monosynaptically activated from group Ia afferents. J Physiol 215:613–636CrossRefGoogle Scholar
Burke RE, Fedina L, Lundberg A (1971) Spatial synaptic distribution of recurrent and group Ia inhibitory systems in cat spinal motoneurones. J Physiol 214:305–326CrossRefGoogle Scholar