Anatomical Science International

, Volume 91, Issue 4, pp 325–333 | Cite as

A multitude of variations in the configuration of the circle of Willis: an autopsy study

  • Wiesława Klimek-Piotrowska
  • Monika Rybicka
  • Aleksandra Wojnarska
  • Agnieszka Wójtowicz
  • Mateusz Koziej
  • Mateusz K. Hołda
Original Article

Abstract

The circle of Willis (CW) is an anastomotic system of arteries located at the base of the brain. The aim of the study was to evaluate the anatomic configuration of the CW in the Polish population and to compare results with previously conducted research. Brains were obtained from 100 recently deceased human adults, and the diameters of cerebral vessels were measured using a slide caliper. Cerebral vessels were observed, paying attention to their origin, diameter, typical configuration and variations. Twenty-seven percent of cases presented the typical literature pattern. The remaining 73 % of all cases were atypical; in 16 % the CW was incomplete and in 57 % complete. Atypical findings involved the posterior communicating artery (PcomA), 62 %; anterior communicating artery (AcomA), 22 %; anterior cerebral artery (ACA), 14 %; posterior cerebral artery (PCA), 8 %. The most common variations were bilateral hypoplastic PcomAs (27 % of cases) and unilateral hypoplastic PcomAs (19 % of cases). Only 9 of the 22 types of CW variations classified previously in the literature were observed, and 26 variations (36 cases) in our study were labeled as ‘other’ type. Mean diameter values for typical CW patterns were internal carotid artery = 3.6 mm, ACA = 2.3 mm, AcomA = 1.9 mm, PCA = 2.2 mm and PcomA = 1.4 mm. Circle of Willis variations have a large impact on clinical practice. This study shows many rare variations that should be taken into consideration to avoid any unexpected complications during surgical procedures involving cerebral vessels.

Keywords

Circle of Willis Anterior communicating artery Anterior cerebral artery Posterior communicating artery Posterior cerebral artery Internal carotid artery 

Abbreviations

CW

Circle of Willis

AcomA

Anterior communicating artery

ACA

Anterior cerebral artery

ICA

Internal carotid artery

PCA

Posterior cerebral artery

PcomA

Posterior communicating artery

CTA

Computed tomography angiography

uSCP

Unilateral selective cerebral perfusion

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Copyright information

© Japanese Association of Anatomists 2015

Authors and Affiliations

  • Wiesława Klimek-Piotrowska
    • 1
  • Monika Rybicka
    • 1
  • Aleksandra Wojnarska
    • 1
  • Agnieszka Wójtowicz
    • 1
  • Mateusz Koziej
    • 1
  • Mateusz K. Hołda
    • 1
  1. 1.Department of AnatomyJagiellonian University Medical CollegeKrakowPoland

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