Tumeurs malignes primitives des paupières : aspects cliniques et épidémiologiques

  • A. Chebbi
  • N. Ben Aleya
  • H. Lajmi
  • I. Malek
  • I. Zeghal
  • H. Bouguila
  • L. Nacef
Article Original / Original Article
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Résumé

Introduction

Les tumeurs malignes primitives des paupières (TMPP) constituent une pathologie fréquente qui survient surtout chez des sujets âgés. Leurs aspects clinique et anatomopathologique sont variés.

Matériels et méthodes

Étude rétrospective portant sur 85 patients suivis pour TMPP. La malignité a été confirmée par l’examen anatomopathologique des pièces d’exérèse tumorale ou des biopsies tumorales.

Résultats

L’âge moyen de nos patients était de 69 ans. On a retrouvé 8,7 % de cas de xeroderma pigmuntosum et 0,9 % de cas d’albinisme. Les notions d’exposition solaire et de tabagisme ont été notées dans respectivement 34 et 1,3 % des cas. L’atteinte était unilatérale dans 95,7 % et au niveau de la paupière inférieure dans 57,5 % et de la paupière supérieure dans 21,7 %.

Discussion

Les TMPP touchent surtout le sujet âgé ou les sujets jeunes où elles sont de pronostic réservé. Le facteur causal le plus fréquemment évoqué reste l’exposition au soleil. L’aspect clinique de la tumeur peut prédire sur sa malignité, mais c’est l’étude histologique qui pose le diagnostic de certitude.

Conclusion

Le pronostic de cette pathologie est lié à leur extension locorégionale, à leur pouvoir métastatique et au type histologique. Le principal facteur de risque reste l’exposition solaire.

Mots clés

Tumeurs malignes Paupières Facteur de risque Xeroderma pigmentosum Histologie 

Primary malignant tumors of the eyelids: Clinical and epidemiological aspects

Abstract

Introduction

The primary malignant tumors of the eyelids are common especially among the elderly and have varied clinical and pathological aspects.

Materials and Methods

This is a retrospective study, covering 85 patients followed for primary malignancy of the eyelids. The diagnosis of malignancy was confirmed by histological examination of tumor resection specimens or tumor biopsies.

Results

The average age of our patients was 69 years, ranging from 12 to 97 years.We found 8.7% cases of xeroderma pigmentosum and 0.9% cases of albinism. Sun exposure and smoking were found in 34% and 31.3% of cases. The tumor was unilateral in 95.7% of cases and at the lower eyelid in 57.5% and upper eyelid in 21.7%.

Discussion

The primary malignant tumors of the eyelids mainly affect the elderly, but can occur in young subjects in whom they are more aggressive. The causal factor most frequently mentioned is sun exposure. In addition, certain general conditions may favor the development of these tumors. The clinical appearance of the tumor can predict its malignancy, but histological study makes the diagnosis.

Conclusion

The prognosis of this condition is related to their locoregional, metastatic potential, and histological type. The main known risk factor is sun exposure.

Keywords

Malignancies Eyelids Risk factor Xeroderma pigmentosum Histology 
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Copyright information

© Springer-Verlag France 2014

Authors and Affiliations

  • A. Chebbi
    • 1
  • N. Ben Aleya
    • 1
  • H. Lajmi
    • 1
  • I. Malek
    • 1
  • I. Zeghal
    • 1
  • H. Bouguila
    • 1
  • L. Nacef
    • 1
  1. 1.Service A, institut Hedi-Raies d’ophtalmologieTunisTunisie

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