A review of melanin sensor devices
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Knowing how readily the skin produces melanin is invaluable in reducing photochemical and phototherapy overtreatment in dermatology and also in reducing the risk of actinic skin damage and skin cancer from excessive radiant light exposure. The commonly used Fitzpatrick skin type (FST) classification scale is often used to subjectively assess ultraviolet light sensitivity and susceptibility to sunburn following significant sunlight exposure. However, the FST scale falls short in the assessment of nonwhite skin types. Alternatively, commercially available melanin sensor devices, called melanometers, can be used to objectively quantify useful skin parameters such as the epidermal melanin concentration (EMC). This study reviews commercially available melanometers and their use in quantifying epidermal melanin concentration (EMC) and the individual maximum safe radiant exposure (IMSRE) for an individual in clinical, workplace and community settings.
KeywordsMelanin Melanometers Epidermis
Compliance with ethical standards
Conflict of interest
Vangelis George Kanellis declares that he has no conflict of interest.
This article does not contain any studies with human participants or animals performed by the author.
- Bashkatov AN, Genina EA, Kochubey VI, Stolnitz MM, Bashkatova TA, Novikova OV, Peshkova AY, Tuchin VV (2000). Optical properties of melanin in the skin and skinlike phantoms. Proc SPIE 4162:219–226. https://doi.org/10.1117/12.405946
- Bhatnagar A, Kanwar A, Parsad D, De D (2007) Psoralen and ultraviolet A and narrow-band ultraviolet B in inducing stability in vitiligo, assessed by vitiligo disease activity score: an open prospective comparative study. J Eur Acad Dermatol Venereol 21(10):1381–1385. https://doi.org/10.1111/j.1468-3083.2007.02283.x CrossRefGoogle Scholar
- Cheun WL (2004) The chemical structure of melanin. Pigment Cell Res 17(4):422–423. https://doi.org/10.1111/j.1600-0749.2004.00165_1.x CrossRefGoogle Scholar
- Khairallah G, Amouroux M, Plénat F, Rakotomanga P, Soussen C, Marchal F, Delconte A, Chen H & Blondel W. (2018) Spatially resolved spectroscopy for guiding margin delineation during human skin carcinomas resection: first clinical results on diffuse reflectance and autofluorescence spectra and in vivo skin optical properties, Proc. SPIE, 10685, Biophotonics: photonic solutions for better health care VI, 106851J. https://doi.org/10.1117/12.2309516
- Kollias N, Baqer A (1986) On The assessment of melanin in human skin in vivo. Photochem Photobiol 43(1):49–54. https://doi.org/10.1111/j.1751-1097.1986.tb05590.x CrossRefGoogle Scholar
- Nakagawa H, Imokawa G (1996) Characterization of melanogenesis in normal human epidermal melanocytes by chemical and ultrastructural analysis. Pigment Cell Res 9(4):175–178. https://doi.org/10.1111/j.1600-0749.1996.tb00106.x CrossRefGoogle Scholar
- Nisma M, Yanke L, Ryo M, Hwan GC, Allison SD, Jinhua W, Suita Y, Weng QY, Allouche J, Kemeny LV, Hermann, Andrea L, Roider EM, Gray NS, Fisher DE (2017) A UV-independent topical small-molecule approach for melanin production in human skin. Cell Rep 19(11):2177–2184. https://doi.org/10.1016/j.celrep.2017.05.042 CrossRefGoogle Scholar
- Thompson MJW, Jones G, Aitken DA (2018) Constitutive melanin density is associated with higher 25-hydroxyvitamin D and potentially total body BMD in older Caucasian adults via increased sun tolerance and exposure. Osteoporos Int 29(8):1887–1895. https://doi.org/10.1007/s00198-018-4568-8 CrossRefGoogle Scholar
- Van Der Wal M, Bloemen M, Verhaegen P, Tuinebreijer W, De Vet H, Van Zuijlen P, Middelkoop E (2013) Objective color measurements: clinimetric performance of three devices on normal skin and scar tissue. J Burn Care Res 34(3):e187–e194. https://doi.org/10.1097/BCR.0b013e318264bf7d CrossRefGoogle Scholar