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Mycotoxin Research

, Volume 26, Issue 3, pp 181–185 | Cite as

Preliminary exposure assessment of deoxynivalenol and patulin in South Africa

  • Gordon S. ShephardEmail author
  • Liana van der Westhuizen
  • David R. Katerere
  • Maryke Herbst
  • Maya Pineiro
Original Paper

Abstract

Deoxynivalenol (DON) and patulin (PAT) are mycotoxins widely regulated internationally. DON is frequently found in cereals, whereas PAT is commonly found in apple juices. A survey of South African commercial products was conducted on DON levels in maize meal and wheat flours, and on PAT levels in apple juices. DON levels in 23 wheat flour samples (mean of 16 positives, 29 µg/kg) were equal to or below 100 µg/kg and in wheat consumers contributed 6–13% of the provisional maximum tolerable daily intake (PMTDI; 1 µg/kg body weight per day) for DON set by the Joint FAO/WHO Expert Committee on Food Additives (JECFA). Sixteen of 18 maize meal samples were contaminated, with a mean for positive samples of 294 µg/kg, and the probable daily intakes ranged from 3.67 µg/kg body weight per day in rural infants to 1.39 µg/kg body weight per day in urban adults. PAT levels in 20 of 30 apple-juice samples were below the detection level of 10 µg/l. Mean of positive samples was 210 µg/l, with three samples exceeding the South African legal limit of 50 µg/l and the highest level (1,650 µg/l) showing the possibility of a brief but high exposure of 37 µg/kg body weight per day (or 9,250% of the JECFA PMTDI of 0.4 µg/kg body weight per day) in young children.

Keywords

Deoxynivalenol Patulin Exposure assessment South Africa Mycotoxins 

Notes

Acknowledgements

The authors thank the Food and Agriculture Organization of the United Nations for funding under the technical cooperation project (TCP/SAF/3001 T).

References

  1. Arranz I, Derbyshire M, Kroeger K, Mischke C, Stroka J, Anklam E (2005) Liquid chromatographic method for quantitation of patulin at 10 ng/ml in apple-based products intended for infants: interlaboratory study. J AOAC Int 88:518–525PubMedGoogle Scholar
  2. Bhat RV, Beedu SR, Ramakrishna Y, Munshi KL (1989) Outbreak of trichothecene mycotoxicosis associated with consumption of mould-damaged wheat production in Kashmir Valley, India. Lancet 1:35–37CrossRefPubMedGoogle Scholar
  3. Canady RA, Coker RD, Egan SK, Krska R, Kuiper-Goodman T, Olsen M, Pestka J, Resnik S, Schlatter J (2001) Deoxynivalenol. In: Safety evaluation of certain mycotoxins in food. WHO Food Additives Series 47, FAO Food and Nutrition Paper 74. WHO, Geneva, pp 419–555Google Scholar
  4. CAST, Council for Agricultural Science and Technology (2003) Mycotoxins: risks in plant, animal, and human systems. CAST, AmesGoogle Scholar
  5. DAFF (2009) Department of Agriculture, Forestry and Fisheries, Republic of South Africa, Monthly Food Security Bulletin of South Africa: July 2009. Available at: www.nda.agric.za/docs/Cropsestimates/reports.htm (accessed 24 November 2009)
  6. European Commission (EC) (2006) Regulation No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. Off J Eur Union L364:5–24Google Scholar
  7. European Commission (EC) (2007) Regulation No 1126/2007 of 28 September 2007 amending Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards Fusarium toxins in maize and maize products. Off J Eur Union L255:14–17Google Scholar
  8. Hopkins J (1993) Toxicological hazards of patulin. Food Chem Toxicol 31:455–456CrossRefPubMedGoogle Scholar
  9. Katerere DR, Stockenström S, Thembo KM, Balducci G, Shephard GS (2007) Investigation of patulin contamination in apple juice sold in retail outlets in Italy and South Africa. Food Addit Contam 24:630–634CrossRefPubMedGoogle Scholar
  10. Leggott NL, Shephard GS (2001) Patulin in South African commercial apple products. Food Control 12:73–76CrossRefGoogle Scholar
  11. Luo XY (1988) Outbreaks of moldy cereals poisoning in China. Issues in food safety. Toxicology Forum, Washington D.C., pp 56–63Google Scholar
  12. MacDonald SJ, Chan D, Brereton P, Damant A, Wood R (2005) Determination of deoxynivalenol in cereals and cereal products by immunoaffinity column cleanup with liquid chromatography: interlaboratory study. J AOAC Int 88:1197–1204PubMedGoogle Scholar
  13. Mashinini K, Dutton MF (2006) The incidence of fungi and mycotoxins in South Africa wheat and wheat-based products. J Environ Sci Health Part B 41:285–296Google Scholar
  14. Moss MO (2008) Fungi, quality and safety issues in fresh fruits and vegetables. J Appl Microbiol 104:1239–1243CrossRefPubMedGoogle Scholar
  15. Nel JH, Steyn NP (2002) Report on South African food consumption studies undertaken amongst different population groups (1983–2000): Average intakes of foods most commonly consumed. Department of Health, Pretoria, South Africa. Available from: http://www.mrc.ac.za/chronic/foodstudies.htm. Accessed 12 November 2009
  16. Pestka JJ, Zhou H-R, Moon Y, Chung YJ (2004) Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unravelling a paradox. Toxicol Lett 153:61–73CrossRefPubMedGoogle Scholar
  17. SAGL, Southern African Grain Laboratory, Wheat Crop Reports. Available at: www.sagl.co.za. Accessed 12 November 2009
  18. Shephard GS, Leggott NL, Stockenström S, Somdyala NIM, Marasas WFO (2002) Preparation of South African maize porridge: effect on fumonisin mycotoxin levels. S A J Science 98:393–396Google Scholar
  19. Shephard GS, Marasas WFO, Burger H-M, Somdyala NIM, Rheeder JP, Van der Westhuizen L, Gatyeni P, Van Schalkwyk DJ (2007) Exposure assessment for fumonisins in the former Transkei region of South Africa. Food Addit Contam 24:621–629CrossRefPubMedGoogle Scholar
  20. WHO, World Health Organization (1995) Evaluation of certain food additives and contaminants. Forty-fourth Report of the Joint FAO/WHO Expert Committee on Food Additives, Technical Report Series 859. WHO, Geneva, pp 36-38Google Scholar

Copyright information

© Society for Mycotoxin Research and Springer 2010

Authors and Affiliations

  • Gordon S. Shephard
    • 1
    Email author
  • Liana van der Westhuizen
    • 1
  • David R. Katerere
    • 1
  • Maryke Herbst
    • 2
  • Maya Pineiro
    • 3
  1. 1.PROMEC UnitMedical Research CouncilTygerbergSouth Africa
  2. 2.Food ControlNational Department of HealthPretoriaSouth Africa
  3. 3.Food and Agriculture Organization of the United NationsRegional Office for Latin America and the CaribbeanSantiagoChile

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