A desktop multi-material 3D bio-printing system with open-source hardware and software

  • Jaehoo Lee
  • Kyu Eon Kim
  • Sumi Bang
  • Insup Noh
  • Chibum LeeEmail author
Regular Paper


Three-dimensional (3D) printing technology is considered to be a major driving innovation in tissue engineering, since a custom-made manufacturing for patients is essential for tissue and organ generation. Depending on the bio-materials and the applications, various 3D bio-printing technologies are used. A system capable of printing a variety of bio-materials through various methods is required for fabrication of hybrid scaffolds for tissue engineering research. This paper describes the design and integration of a multi-channel 3D bio-printing system at an affordable price based on open source hardware and software. The hardware and software components of the 3D bio-printing system and the process of finding optimal printing conditions are described in the paper. Fabrication of the hybrid scaffold of synthetic polymer and cell loaded hydrogel are presented to validate the performance of the system.


3D printing Multi-material bio-printing 3D bio-printing system Scaffold Design of experiment Open-source 


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Copyright information

© Korean Society for Precision Engineering and Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Jaehoo Lee
    • 1
  • Kyu Eon Kim
    • 1
  • Sumi Bang
    • 3
  • Insup Noh
    • 2
    • 3
  • Chibum Lee
    • 1
    Email author
  1. 1.Department of Mechanical System & Design EngineeringSeoul National University of Science and TechnologySeoulSouth Korea
  2. 2.Department of Chemical & Biomolecular EngineeringSeoul National University of Science and TechnologySeoulSouth Korea
  3. 3.Convergence Institute of Biomedical Engineering & BiomaterialsSeoul National University of Science and TechnologySeoulSouth Korea

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